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ClinicalTrials.gov public records Last synced Nov 9, 2026, 5:44 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 308 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Surgical Wound Infection Clear all

Conditions: Surgical Site Infection
Interventions: IrriSept System, No Intervention - Standard of Care (SoC) only; Device · Other
Lead sponsor: Irrimax Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 627 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 17
States / cities: Tucson, Arizona • Los Angeles, California • Denver, Colorado + 14 more

Conditions: Laparotomy, Dehiscence Wound, Surgical Site Infections, Trauma Abdomen, Emergency General Surgery
Interventions: triclosan-coated barbed suture, triclosan-coated non-barbed suture, Non-coated non-barbed suture; Device
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years to 100 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Surgical Wound Infection
Interventions: Prevena; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 80 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Surgical Site Infection, Groin Infections
Interventions: Negative Pressure Pressure Wound Therapy, Standard Wound Care; Device · Procedure
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Hidradenitis Suppurativa, Surgical Wound
Interventions: Wet-to-Dry Dressings, Petrolatum with Non-Stick Gauze; Device
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 16 Years to 99 Years
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Infection of Total Hip Joint Prosthesis
Interventions: Prevena Incision Management System; Device
Lead sponsor: ProMedica Health System; Other
Eligibility: 18 Years to 85 Years
Enrollment: 248 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Toledo, Ohio

Conditions: Surgical Site Infection
Interventions: Chlorhexidine Gluconate 2% Wipe, Theraworx Bath Wipes; Drug · Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 64 Years
Enrollment: 203 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Surgical Site Infection, Breast Reconstruction, Antibiotic Use
Interventions: Single pre-operative dose of intravenous antibiotics with intraoperative redosing, One week of post-operative antibiotics; Drug
Lead sponsor: The Plastic Surgery Foundation; Other
Eligibility: 18 Years and older · Female only
Enrollment: 235 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 5
States / cities: Chicago, Illinois • Baltimore, Maryland • Ann Arbor, Michigan + 2 more

Conditions: Surgical Site Infection
Interventions: topical irrigation with gentamicin (80mg diluted in 1L 0.9% normal saline), topical irrigation with sterile normal saline (NS), intravenous (IV) prophylactic antibiotic; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Colon Cancer, Pancreatic Cancer, Perioperative/Postoperative Complications, Primary Peritoneal Cavity Cancer, Rectal Cancer
Interventions: wound care management; Procedure
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 375 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Wound Infection
Interventions: Purse string closure, Primary closure; Procedure
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Wound Infection and Wound Healing
Interventions: MyHealthPal App; Device
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Chestnut Hill, Massachusetts

Conditions: Surgical Wound Infection
Interventions: Warming of surgical incision, Warming dressing without actual warming; Other
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 146 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Surgical Site Infection Following Cesarean Delivery
Interventions: Iodine povidone, Chlorhexidine, Combination iodine and chlorhexidine; Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 1,404 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 2
States / cities: The Bronx, New York

Conditions: Surgical Wound Infection, Preoperative Care, Methicillin-Resistant Staphylococcus Aureus
Interventions: Povidone-Iodine 10%, 0.9% NaCl Solution; Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 80 Years
Enrollment: 192 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Patients Undergoing Hepatopancreatobiliary Surgery
Interventions: Conventional wound therapy, Negative pressure wound therapy; Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2021
U.S. locations: 2
States / cities: Indianapolis, Indiana • Durham, North Carolina

Conditions: Suture, Complication, Wound, Wound Complication, Wound Dehiscence, Wound of Skin, Surgery, Suture; Complications, Infection or Inflammation
Interventions: Suture spacing for wound closure; Other
Lead sponsor: Silver Falls Dermatology; Other
Eligibility: 30 Years to 100 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Salem, Oregon

Conditions: Surgical Wound Infection, Spinal Deformity, Spinal Degeneration
Interventions: Antibiotic Protocol; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 539 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Emergency Surgery, Surgical Site Infections
Interventions: Chlorhexidine, Normal Saline; Drug
Lead sponsor: The University of Texas Health Science Center at Tyler; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Tyler, Texas

Conditions: Abscess, Wound Infection, Surgical Site Infection, Cellulitis
Interventions: Dalbavancin, Dalbavancin-matching Placebo; Drug
Lead sponsor: Durata Therapeutics Inc., an affiliate of Allergan plc; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 698 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 25
States / cities: Montgomery, Alabama • Anaheim, California • Long Beach, California + 18 more

Conditions: Sepsis
Interventions: CNA Rapid Sepsis Dx; Diagnostic Test
Lead sponsor: Robert Ehrman; Other
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 5
States / cities: Birmingham, Alabama • Detroit, Michigan • New York, New York

Conditions: Wound Heal
Interventions: Electroceutical Dressing Technology-EDThi, Adding EDTlo (Procellera®) for 3 weeks after use of EDThi; Device
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 112 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 3
States / cities: Indianapolis, Indiana

Conditions: Colorectal Neoplasms, Diverticulitis, Inflammatory Bowel Diseases, Surgical Site Infection
Interventions: Polyethylene Glycol, Neomycin, Metronidazole Hydrochloride, Therapeutic Conventional Surgery; Drug · Procedure
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 19 Years and older
Enrollment: 224 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Surgery, Anaesthesia, Ventilator-Induced Lung Injury, Lung Injury, Pneumonia, Pneumothorax, Respiratory Distress Syndrome, Adult, Respiratory Insufficiency
Interventions: Not listed
Lead sponsor: European Society of Anaesthesiology; Other
Eligibility: 18 Years and older
Enrollment: 10,690 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 3
States / cities: Aurora, Colorado • Boston, Massachusetts • Rochester, Minnesota

Search by objective public record fields.

Irrisept Versus Standard of Care in the Prevention of Surgical Site Infections

Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT

Prophylactic NPWT to Reduce SSI in Colorectal Surgery

Negative Pressure Wound Therapy for Surgical Site Infection Prevention in Common Femoral Artery Exposure

Wet-to-dry vs Petrolatum & Non-stick Dressings After Hidradenitis Suppurativa Surgery

Evaluating Advantages of Prevena After Hip and Knee Arthroplasty

Preadmission Skin Wipe Use for Surgical Site Infection Prophylaxis in Adult Orthopaedic Surgery Patients

Surgical Site Infection and Antibiotic Use Study

Topical Antibiotic Irrigation (Gentamicin) in Prophylaxis of Midfacial Fracture Surgical Wounds

Negative Pressure Therapy in Preventing Infection After Surgery in Patients With Colon, Rectal, Pancreatic, or Peritoneal Surface Cancer

A Randomized Trial of Ostomy Closure Techniques

Post-Surgery Wound Healing Tracking With MyHealthPal App

Local Warming of Surgical Incisions

Comparison of Surgical Skin Preps During Cesarean Deliveries

Povidone-Iodine for Nasal Decolonization

Negative Pressure Wound Therapy to Reduce Surgical Site Infection

Split Scar Study to Assess Cosmetic Outcome From Differing Suture Spacing

Comparison of Antibiotic Protocols in Spine Patients With Postoperative Drains

Irrisept in Emergency General Surgery Patients

Single Dose vs. Two Dose Regimen of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Preclinical Detection of Sepsis Early in Hospitalized Patients Following Surgery, Injury or Severe Illness

Electroceutical Dressing Technology (EDT) Against Wound Microbial Biofilm Infection

Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery

Local Assessment of Ventilatory Management During General Anesthesia for Surgery