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ClinicalTrials.gov public records Last synced Jul 21, 2026, 12:47 PM EDT

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Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Syncope, Vasovagal Clear all
Completed Phase 2 Interventional Results available

The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near Syncope

NCT04972123
View directory record Official record
Conditions
Syncope, Vasovagal
Interventions
CPC - Capsaicin, Phenylephrine, Caffeine, Tilt Table Test, Placebo
Drug · Diagnostic Test
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 50 Years
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 16, 2024 · Synced Jul 21, 2026, 12:47 PM EDT
Completed Not applicable Interventional Results available

Aveir DR i2i Study

NCT05252702
View directory record Official record
Conditions
Cardiac Pacemaker, Artificial, Cardiac Rhythm Disorder, Bradycardia
Interventions
Aveir DR Leadless Pacemaker System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
464 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
54
States / cities
Scottsdale, Arizona • Jonesboro, Arkansas • Little Rock, Arkansas + 44 more
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Jul 21, 2026, 12:47 PM EDT
Completed Not applicable Interventional Results available

Preventing Post-Vaccination Presyncope and Syncope in Adolescents Using Simple, Clinic-based Interventions: A Pilot Study

NCT03533829
View directory record Official record
Conditions
Syncope, Vasovagal
Interventions
Buzzy®, Music
Device · Behavioral
Lead sponsor
Duke University
Other
Eligibility
10 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
2
States / cities
Atlanta, Georgia • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2019 · Synced Jul 21, 2026, 12:47 PM EDT
Completed Not applicable Interventional

Addressing Fear and Risk of Vasovagal Reactions Among High School Donors

NCT03835299
View directory record Official record
Conditions
Blood Donors
Interventions
Fear Intervention
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
16 Years and older
Enrollment
4,035 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2021 · Synced Jul 21, 2026, 12:47 PM EDT
Completed Phase 4 Interventional

Propranolol to Treat Fainting Due to Sympathoadrenal Imbalance

NCT00060866
View directory record Official record
Conditions
Neurocardiogenic Syncope
Interventions
Propranolol
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 21, 2026, 12:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Hypnosis in Autonomic Function

NCT00061009
View directory record Official record
Conditions
Vasovagal Syncope, Postural Tachycardia Syndrome, Hypnosis
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 21, 2026, 12:47 PM EDT
Completed Phase 2 Interventional

Propranolol to Treat Fainting in Children With Sympathoadrenal Imbalance

NCT00093860
View directory record Official record
Conditions
Syncope
Interventions
Propranolol
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 21, 2026, 12:47 PM EDT
Completed Not applicable Interventional Results available

Cardioneuroablation for Neurocardiogenic Syncope

NCT02009982
View directory record Official record
Conditions
Neurocardiogenic Syncope, Vasovagal Syncope
Interventions
Cardioneuroablation, Biosense Webster Navistar ThermoCool Diagnostic/Ablation Deflectable Tip Catheter
Procedure · Device
Lead sponsor
David B. De Lurgio
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Atlanta, Georgia • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 3, 2016 · Synced Jul 21, 2026, 12:47 PM EDT
Completed Phase 2 Interventional

Non-Pharmacologic Therapy for Neurocardiogenic Syncope

NCT00096902
View directory record Official record
Conditions
Syncope
Interventions
Tilt table test
Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 21, 2026, 12:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Chronic Orthostatic Intolerance

NCT00069693
View directory record Official record
Conditions
Syncope
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
10 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 21, 2026, 12:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

PET Scan in Patients With Neurocardiologic Disorders

NCT00001418
View directory record Official record
Conditions
Autonomic Nervous System Diseases
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
335 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1994 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 21, 2026, 12:47 PM EDT
Completed Phase 4 Interventional Results available

Clinical Trial for the Prevention of Vasovagal Syncope

NCT00118482
View directory record Official record
Conditions
Syncope, Vasovagal, Neurally-Mediated
Interventions
fludrocortisone acetate
Drug
Lead sponsor
University of Calgary
Other
Eligibility
14 Years and older
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
3
States / cities
Boston, Massachusetts • Nashville, Tennessee • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 14, 2019 · Synced Jul 21, 2026, 12:47 PM EDT
Recruiting No phase listed Observational

Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD Registry

NCT06166277
View directory record Official record
Conditions
Vasovagal Syncope, AV Block-2Nd Degree-Type 1, Sinus Pause
Interventions
Ablation procedure
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
300 participants
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Jul 21, 2026, 12:47 PM EDT
Not listed Phase 4 Interventional

Assessment of Midodrine in the Prevention of Vasovagal Syncope: The Prevention of Syncope Trial IV

NCT01456481
View directory record Official record
Conditions
Vasovagal Syncope
Interventions
midodrine hydrochloride, matching placebo
Drug
Lead sponsor
Dr. Bob Sheldon
Other
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2024
U.S. locations
2
States / cities
Minneapolis, Minnesota • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Jul 21, 2026, 12:47 PM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Reducing Orthostatic Intolerance With Oral Rehydration in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients

NCT02854683
View directory record Official record
Conditions
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis, Systemic Exertion Intolerance Disease (SEID), Postural Tachycardia Syndrome (POTS), Neurally Mediated Syncope (NMS)
Interventions
Normal Saline, Oral Rehydration Solution
Drug · Dietary Supplement
Lead sponsor
New York Medical College
Other
Eligibility
15 Years to 29 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Hawthorne, New York
Source: ClinicalTrials.gov public record
Updated Jun 9, 2021 · Synced Jul 21, 2026, 12:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

MRI to Assess the Effects of Dysautonomia and Chronic Nausea on Brain Transmitters

NCT01692561
View directory record Official record
Conditions
Dysautonomia
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
9 Years to 18 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2018 · Synced Jul 21, 2026, 12:47 PM EDT
Completed Early Phase 1 Interventional

Influence of Yoga in Patients With Neurocardiogenic Syncope

NCT01695525
View directory record Official record
Conditions
Syncope, Vasovagal
Interventions
Yoga
Other
Lead sponsor
Dhanunjaya Lakkireddy, MD, FACC
Other
Eligibility
18 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 29, 2015 · Synced Jul 21, 2026, 12:47 PM EDT
Recruiting No phase listed Observational

Fainting Detection And Early Warning In Syncope Evaluation Study (ARISE)

NCT07502599
View directory record Official record
Conditions
Orthostatic Hypotension, Reflex Syncope
Interventions
Wearable holter monitor
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Jul 21, 2026, 12:47 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic

NCT00921986
View directory record Official record
Conditions
Arrhythmias, Cardiac
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2035
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Jul 21, 2026, 12:47 PM EDT
Completed No phase listed Observational

Tilt Table With Suspected Postural Orthostatic Tachycardia Syndrome (POTS) Subjects

NCT01617616
View directory record Official record
Conditions
Postural Orthostatic Tachycardia Syndrome, Syncope, Vasovagal, Neurocardiogenic Syncope
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
10 Years to 21 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 19, 2017 · Synced Jul 21, 2026, 12:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Presyncope (Syncope) Prevention Study

NCT04772755
View directory record Official record
Conditions
Syncope, Vasovagal
Interventions
Buzzy® and Electronic Game
Device
Lead sponsor
Duke University
Other
Eligibility
10 Years to 14 Years
Enrollment
338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Atlanta, Georgia • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Jul 21, 2026, 12:47 PM EDT
Recruiting No phase listed Observational

Aveir DR Real-World Evidence Post-Approval Study

NCT05935007
View directory record Official record
Conditions
Cardiac Pacemaker, Arrythmia, Bradycardia
Interventions
Aveir DR Leadless Pacemaker System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,805 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Sylmar, California
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Jul 21, 2026, 12:47 PM EDT
Terminated No phase listed Observational

Clinical Autonomic Disorders: A Training Protocol

NCT02154009
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Pseudopheochromocytoma, Healthy Volunteers, Neurocardiogenic Syncope, Postural Tachycardia Syndrome
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
2 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Jul 21, 2026, 12:47 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Mechanisms of Vasovagal Syncope

NCT01791816
View directory record Official record
Conditions
Vasovagal Syncope, Postural Tachycardia Syndrome
Interventions
Phenylephrine, L-Ng-monomethyl Arginine (L-NMMA)
Drug
Lead sponsor
New York Medical College
Other
Eligibility
14 Years to 29 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2022
U.S. locations
1
States / cities
Hawthorne, New York
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Jul 21, 2026, 12:47 PM EDT