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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: THA Clear all
Active, not recruiting No phase listed Observational

Zimmer Continuum Metal on Polyethylene (MoP) PostMarket Clinical Followup (PMCF) Study

NCT01307384
View directory record Official record
Conditions
Avascular Necrosis, Osteoarthritis, Inflammatory Arthritis, Post-traumatic Arthritis, Rheumatoid Arthritis
Interventions
Continuum Metal on Polyethylene Acetabular System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 75 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2027
U.S. locations
2
States / cities
Fremont, California • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 17, 2025 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Trial Comparing Impact of PENG Block on Quality of Recovery Compared to No-block for Primary Total Hip Arthroplasty

NCT04591353
View directory record Official record
Conditions
Total Hip Arthroplasty
Interventions
PENG Block, Lidocaine
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Jul 23, 2026, 1:26 AM EDT
Recruiting Phase 3 Interventional

Methadone in THA for Post-op Pain and Opioid Reduction

NCT07227064
View directory record Official record
Conditions
Post Operative Pain, Total Hip Arthroplasty
Interventions
Methadone
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Phase 1 Interventional Results available

Dose Dependent Effects of tDCS on Post-Operative Pain

NCT02241967
View directory record Official record
Conditions
Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty(Postoperative Pain)
Interventions
4 Real sessions of Transcranial Direct Current Stimulation, 2 Real Sessions of Transcranial Direct Current Stimulation, 1 Real Session of Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
19 Years to 90 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 12, 2022 · Synced Jul 23, 2026, 1:26 AM EDT
Active, not recruiting Phase 4 Interventional

Dual Mobility in "High Risk" Patients

NCT04092634
View directory record Official record
Conditions
Dislocation, Hip
Interventions
Dual mobility implant, Traditional, Single-bearing hip implant
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
412 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2035
U.S. locations
4
States / cities
Los Angeles, California • Chicago, Illinois • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Total Hip Arthroplasty (THA) Surgical Techniques Comparing the Direct Anterior Approach to the Posterior Approach

NCT01807104
View directory record Official record
Conditions
Osteoarthritis of the Hip
Interventions
Anterior Approach / Posterior Approach, Anterior versus Posterior Approach for total hip replacement
Procedure
Lead sponsor
Barrett, William, M.D.
Individual
Eligibility
20 Years to 75 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Renton, Washington
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Anterior Capsulectomy vs. Repair in Direct Anterior THA

NCT01621932
View directory record Official record
Conditions
Total Hip Arthroplasty
Interventions
Direct anterior approach with capsulectomy, Direct anterior approach without capsulectomy
Procedure
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Jul 23, 2026, 1:26 AM EDT
Recruiting No phase listed Observational

Polyethylene Wear Particle Analysis of THA

NCT06432543
View directory record Official record
Conditions
Wear of Articular Bearing Surface of Prosthetic Joint, Hip Arthropathy
Interventions
polyethylene
Device
Lead sponsor
Osaka Metropolitan University
Other
Eligibility
20 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 19, 2025 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Phase 1 Interventional

Tissue Distribution, Pharmacokinetics, Safety, and Tolerability After a Single Dose of TNP-2092 in Participants Undergoing Primary Total Hip or Knee Arthroplasty

NCT04294862
View directory record Official record
Conditions
Prosthetic Joint Infection
Interventions
TNP-2092
Drug
Lead sponsor
TenNor Therapeutics Limited
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Jul 23, 2026, 1:26 AM EDT
Terminated Not applicable Interventional

Total Joint Arthroplasty (TJA) Weight Loss Study

NCT05156762
View directory record Official record
Conditions
Osteoarthritis, Hip, Osteoarthritis, Knee, Obesity, Morbid
Interventions
Bariatric surgery, Medical weight loss, Patient research surveys, Total joint arthroplasty (TJA), Usual standard of care
Procedure · Behavioral · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Jul 23, 2026, 1:26 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

ROSA® Hip System THA PMCF

NCT05497206
View directory record Official record
Conditions
Osteoarthritis, Hip, Avascular Necrosis of Hip
Interventions
One of the following hip implants may be used within this arm of the study: G7 Acetabular System, Taperloc Complete System, Avenir and Avenir Complete Systems, and Echo Bi-Metric System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
2
States / cities
Jacksonville, Florida • Saint Joseph, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Jul 23, 2026, 1:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Vitamin D and Functional Outcomes After Total Hip Arthroplasty (THA)

NCT01397383
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Not listed
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
40 Years and older
Enrollment
219 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 19, 2017 · Synced Jul 23, 2026, 1:26 AM EDT
Not listed Not applicable Interventional

Multi-Site, Post-Market Study of the ICONACY I-Hip System

NCT02131389
View directory record Official record
Conditions
Degenerative Joint Disease
Interventions
Iconacy Hip System
Device
Lead sponsor
Iconacy Orthopedic Implants, LLC.
Industry
Eligibility
30 Years to 80 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated May 5, 2014 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Comparison of Negative Pressure Wound Therapy vs. Conventional Dressings for Prevention of Wound Complications After Revision THA

NCT03321799
View directory record Official record
Conditions
Infection, Drainage
Interventions
Negative Pressure Wound Therapy (NPWT), Sterile Antimicrobial Dressings
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Jul 23, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional

Influence of Antiseptic Washes on Wound Healing Complications After THA

NCT07104084
View directory record Official record
Conditions
Hip Osteoarthritis, Avascular Necrosis of Femur Head
Interventions
lavage chlorhexidine, lavage povidone-iodine
Device
Lead sponsor
F. Johannes Plate
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Monroeville, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional Results available

Deep Vein Thrombosis (DVT) Prevention in Total Hip Arthroplasty: Continuous Enhanced Circulation Therapy (CECT) Versus Low Molecular Weight Heparin (LMWH)

NCT00358735
View directory record Official record
Conditions
Deep Vein Thrombosis of Lower Limb, Pulmonary Embolism (PE), Bleeding
Interventions
ActiveCare CECT device, Enoxaparin
Device · Drug
Lead sponsor
Medical Compression Systems
Industry
Eligibility
18 Years and older
Enrollment
411 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
9
States / cities
La Jolla, California • Loma Linda, California • Los Angeles, California + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2014 · Synced Jul 23, 2026, 1:26 AM EDT
Terminated Phase 2 Interventional

Efficacy and Safety Study of 4975 in Patients Undergoing Total Hip Replacement

NCT00683267
View directory record Official record
Conditions
Arthroplasty
Interventions
4975, highly purified capsaicin, Placebo
Drug
Lead sponsor
Anesiva, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
10
States / cities
Birmingham, Alabama • Arcadia, California • Glendale, California + 7 more
Source: ClinicalTrials.gov public record
Updated May 3, 2009 · Synced Jul 23, 2026, 1:26 AM EDT
Recruiting Phase 4 Interventional

Duloxetine for Perioperative Pain in Hip Arthroplasty: A RCT

NCT06807866
View directory record Official record
Conditions
THA
Interventions
Duloxetine, Placebo
Drug · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Epsilon Aminocaproic Acid (EACA) for the Reduction of Blood Loss in Total Hip Arthroplasty (THA)

NCT01391182
View directory record Official record
Conditions
Degenerative Joint Disease, Osteoarthritis
Interventions
EACA, Placebo arm
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 25, 2015 · Synced Jul 23, 2026, 1:26 AM EDT
Not listed Not applicable Interventional

KINCISE™ Surgical Automated System in Total Hip Arthroplasty (THA)

NCT05223777
View directory record Official record
Conditions
Osteoarthritis, Hip
Interventions
KINCISE, Traditional Handheld Mallet
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Jul 23, 2026, 1:26 AM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Suzetrigine in Total Hip Arthroplasty

NCT07226700
View directory record Official record
Conditions
Total Hip Arthroplasty (THA), Total Hip Arthroplasty \(THA\), Total Hip Replacement, Total Hip Replacement Surgery, Total Hip Replacements, Total Hip Replacement Arthroplasty, Suzetrigine, Pain Management, Pain, Nav 1.8, JOURNAVX, Opioid Cessation, Opioid Consumption, Postoperative, Multimodal Analgesia, Randomized Controlled Trial, Randomized Controlled Study, Randomized Controlled Trials
Interventions
Suzetrigine, Placebo
Drug · Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family to Family: Psychoeducation to Improve Children's Outcomes in HIV+ Families

NCT01037946
View directory record Official record
Conditions
Quality of Life, Family Relations, Mental Health, Physical Health
Interventions
Cognitive behavioral sessions
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
1,033 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 23, 2012 · Synced Jul 23, 2026, 1:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Calcium Absorption in Postmenopausal Thai Women

NCT02291315
View directory record Official record
Conditions
Fractional Calcium Absorption
Interventions
Not listed
Lead sponsor
Cornell University
Other
Eligibility
53 Years to 65 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2014 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Efficacy of Aquamantys for Reducing Transfusions With Anterior Supine Intermuscular Approach Total Hip Arthroplasty

NCT01583465
View directory record Official record
Conditions
Osteoarthritis, Hip, Joint Deformities, Acquired, Hip Dislocation, Congenital, Osteonecrosis, Arthritis, Rheumatoid
Interventions
Aquamantys, standard electrocautery (Bovie)
Device
Lead sponsor
Joint Implant Surgeons, Inc.
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
New Albany, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 23, 2012 · Synced Jul 23, 2026, 1:26 AM EDT