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ClinicalTrials.gov public records Last synced Sep 9, 2026, 7:56 PM EDT

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Showing 1–24 of 286 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Temperature Change, Body Clear all
Withdrawn No phase listed Observational Accepts healthy volunteers

Continuous Temperature Measurement for Syndromic Surveillance

NCT03345277
View directory record Official record
Conditions
Continuous Temperature, Syndromic Surveillance, Long-term Care
Interventions
Continuous Temperature monitoring
Other
Lead sponsor
Avera McKennan Hospital & University Health Center
Other
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Jul 4, 2019 · Synced Sep 9, 2026, 7:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Accelerating Post-exercise Muscle Glycogen Resynthesis in Humans: Impact of Combined Nutrient Intake and Intermittent Pneumatic Compression or Heat Therapy

NCT04371237
View directory record Official record
Conditions
Muscle Recovery, Muscle Soreness, Glycogen Depletion
Interventions
Compression sleeve, Heat therapy, Glycogen-depleting exercise session, Nutrient Intake (beverage), Skeletal muscle biopsy
Device · Other · Procedure
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 35 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Sep 9, 2026, 7:56 PM EDT
Withdrawn Phase 2 Interventional

REperfusion With Cooling in CerebraL Acute IscheMia II

NCT02411877
View directory record Official record
Conditions
Ischemic Stroke, Hypothermia
Interventions
Normothermia, Mild hypothermia, Trevo Pro Retriever (Stryker Corp.), Zoll Thermogard XP technology with the Quattro catheter
Procedure · Device
Lead sponsor
WellStar Health System
Other
Eligibility
18 Years to 79 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 16, 2016 · Synced Sep 9, 2026, 7:56 PM EDT
Withdrawn Phase 3 Interventional

Fever and Neutropenia in Pediatric Oncology Patients

NCT03768869
View directory record Official record
Conditions
Fever, Neutropenia
Interventions
Low Risk: Oupatient Management, Low Risk: Inpatient Management, High Risk: Inpatient Management
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
0 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 26, 2021 · Synced Sep 9, 2026, 7:56 PM EDT
Completed No phase listed Observational

Effects of Monopolar Electrocautery Use During Surgery on Implanted Cardiac Defibrillators

NCT01572246
View directory record Official record
Conditions
Heart Failure, Tachycardia, Ventricular
Interventions
Optimal placement of return pad
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Sep 9, 2026, 7:56 PM EDT
Completed Not applicable Interventional Results available

Transnasal Induction of Normothermia in Febrile Stroke Patients

NCT03360656
View directory record Official record
Conditions
Stroke, Ischemic, Stroke Hemorrhagic, Fever, Seizures, Metabolic Encephalopathy
Interventions
Transnasal Thermal Regulating Device
Device
Lead sponsor
CoolTech LLC
Industry
Eligibility
18 Years to 95 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 17, 2023 · Synced Sep 9, 2026, 7:56 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

IEEM- Work:Rest Cycles in Burn Survivors- Humidity

NCT06966336
View directory record Official record
Conditions
Hyperthermia, Burn Injury
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 9, 2026, 7:56 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for Heat

NCT06475339
View directory record Official record
Conditions
Hyperthermia, Fatigue; Heat
Interventions
30/30 work/rest cycle, 30/20 work/rest cycle, 40/30 work/rest cycle, 20/12 work/rest cycle
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 39 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Sep 9, 2026, 7:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Novel Cooling Vest to Protect Persons With SCI From Hyperthermia

NCT05441449
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Cooling Vest
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 68 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Sep 9, 2026, 7:56 PM EDT
Terminated No phase listed Observational

Quantifying and Understanding the Signs and Symptoms of Fever

NCT01287143
View directory record Official record
Conditions
Fever
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 100 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Sep 9, 2026, 7:56 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Safety of RSV Preventive Monoclonal Antibody

NCT07158814
View directory record Official record
Conditions
Fever, Adverse Event Following Immunisation
Interventions
Respiratory Syncytial Virus (RSV) Preventive Monoclonal Antibody
Drug
Lead sponsor
Duke University
Other
Eligibility
6 Weeks to 30 Weeks
Enrollment
524 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
6
States / cities
Oakland, California • Atlanta, Georgia • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 9, 2026, 7:56 PM EDT
Completed Phase 2 Interventional Results available

Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia

NCT02530515
View directory record Official record
Conditions
Anemia, Cancer Fatigue, Chronic Lymphocytic Leukemia, Fever, Infectious Disorder, Lymphadenopathy, Lymphocytosis, Night Sweats, Prolymphocytic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Richter Syndrome, Secondary Malignant Neoplasm, Thrombocytopenia, Weight Loss
Interventions
Ex Vivo-activated Autologous Lymph Node Lymphocytes, Laboratory Biomarker Analysis
Biological · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 28, 2019 · Synced Sep 9, 2026, 7:56 PM EDT
Recruiting Not applicable Interventional

Repeated Far Infrared Sauna Bathing in Adults With Obesity

NCT07158047
View directory record Official record
Conditions
Obesity (Disorder)
Interventions
Heat therapy
Other
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 59 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 9, 2026, 7:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cold Water Immersion Stirring in Hyperthermic Individuals

NCT04613843
View directory record Official record
Conditions
Hyperthermia
Interventions
Water Stirring, No Water Stirring
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 39 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jul 25, 2022 · Synced Sep 9, 2026, 7:56 PM EDT
Completed No phase listed Observational

Impact of Swab Site and Sample Collector on Testing Sensitivity for COVID-19 Virus in Symptomatic Individuals

NCT04321369
View directory record Official record
Conditions
Infections, Respiratory, Fever, Cough
Interventions
Testing Sensitivity for SARS-CoV-2 Virus in Symptomatic Individuals
Diagnostic Test
Lead sponsor
UnitedHealth Group
Industry
Eligibility
Not listed
Enrollment
530 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Sep 9, 2026, 7:56 PM EDT
Not listed Phase 3 Interventional

Levofloxacin Compared With Cefepime in Treating Cancer Patients With Fever and Neutropenia

NCT00020865
View directory record Official record
Conditions
Fever, Sweats, and Hot Flashes, Infection, Leukemia, Lymphoma, Neutropenia, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
cefepime hydrochloride, levofloxacin
Drug
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2001
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 18, 2013 · Synced Sep 9, 2026, 7:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Warming Garment in the Perioperative Period With Integrated Chemical Heat Packs to Maintain Normothermia

NCT02905708
View directory record Official record
Conditions
Hypothermia
Interventions
Air-Activated heating packs, Forced Air Warming Device
Device
Lead sponsor
Dr K Services PC
Other
Eligibility
18 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Norwalk, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 13, 2017 · Synced Sep 9, 2026, 7:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Validity of CORE Sensor in Heat Training for Male and Female Endurance Athletes

NCT05692947
View directory record Official record
Conditions
Temperature Change, Body
Interventions
Core body temperature device
Device
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 59 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 9, 2026, 7:56 PM EDT
Completed Not applicable Interventional Results available

Accuracy of the Drager Dual-sensor Temperature Measurement System

NCT00980642
View directory record Official record
Conditions
Hypothermia; Anesthesia
Interventions
Draeger double-sensor, Esophageal stethoscope temperature sensor, Foley catheter temperature sensor
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Sep 9, 2026, 7:56 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Malignant Hyperthermia Registry and Genetic Testing

NCT02964481
View directory record Official record
Conditions
Malignant Hyperthermia
Interventions
Whole exome sequencing
Genetic
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Sep 9, 2026, 7:56 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Sauna Detoxification Study: Pilot Feasibility

NCT01576822
View directory record Official record
Conditions
Hyperthermia
Interventions
This protocol will utilize a sauna as the primary method of detoxification.
Other
Lead sponsor
Bastyr University
Other
Eligibility
21 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Kenmore, Washington
Source: ClinicalTrials.gov public record
Updated Oct 29, 2012 · Synced Sep 9, 2026, 7:56 PM EDT
Recruiting Not applicable Interventional

The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia.

NCT07224464
View directory record Official record
Conditions
Metastatic Solid Tumors, Stage 4 Cancer
Interventions
The Sarah Nanotechnology System - intended to deliver thermal energy to malignant cells for the purpose of thermal destruction of these cells in patients with advanced metastatic solid tumors.
Device
Lead sponsor
New Phase Ltd.
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 9, 2026, 7:56 PM EDT
Approved For Marketing No phase listed Expanded access

Compassionate Use Protocol for the Treatment of Autoinflammatory Syndromes

NCT01724580
View directory record Official record
Conditions
Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE), Juvenile Dermatomyositis (JDM), Stimulator of Interferon Genes (STING)-Associated Vasculopathy With Onset During Infancy (SAVI), Aicardi-Goutières Syndrome (AGS)
Interventions
Baricitinib
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
6 Months and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
2
States / cities
Bethesda, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 16, 2025 · Synced Sep 9, 2026, 7:56 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

IEEM-Heat and Heart Failure

NCT06961929
View directory record Official record
Conditions
Heart Failure, Hyperthermia
Interventions
Control Trial, Water-saturated T-shirt trial, Skin-Wetting Trial
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
45 Years and older
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 9, 2026, 7:56 PM EDT