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Showing 1–24 of 46 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Thermal Burn Clear all
Not yet recruiting No phase listed Observational

TDAP in Burn Patients (Group 2)

NCT07223684
View directory record Official record
Conditions
Sepsis, Burn Injury, Wound Healing, Critical Illness, Multiple Organ Dysfunction Syndrome
Interventions
Observational Cohort (No Intervention)
Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
Tampa, Florida • Atlanta, Georgia • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Jul 21, 2026, 6:08 PM EDT
Completed No phase listed Observational

Chronology of Occult and Gross Coagulopathy in Burn Patients

NCT01638481
View directory record Official record
Conditions
Thermal Burns
Interventions
Not listed
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Jul 21, 2026, 6:08 PM EDT
Active, not recruiting Not applicable Interventional

STAT: Standard Therapy Plus Active Therapy

NCT04368117
View directory record Official record
Conditions
Burn Injury, Physical Injury, Thermal Burn
Interventions
Physical Therapy
Behavioral
Lead sponsor
American Burn Association
Other
Eligibility
18 Years to 65 Years
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
7
States / cities
Phoenix, Arizona • Sacramento, California • Maywood, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Jul 21, 2026, 6:08 PM EDT
Not listed Phase 3 Interventional

The RE-ENERGIZE Study: RandomizEd Trial of ENtERal Glutamine to minimIZE Thermal Injury

NCT00985205
View directory record Official record
Conditions
Burns
Interventions
Enteral Glutamine, Placebo
Dietary Supplement
Lead sponsor
Daren K. Heyland
Other
Eligibility
18 Years and older
Enrollment
1,201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2021
U.S. locations
27
States / cities
Mobile, Alabama • Phoenix, Arizona • Los Angeles, California + 24 more
Source: ClinicalTrials.gov public record
Updated Dec 29, 2021 · Synced Jul 21, 2026, 6:08 PM EDT
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

Pilot Studies Testing the Use of Oral Amitriptyline in Reducing Localized Burn Injury-induced Microvesicle Particle Release

NCT07640061
View directory record Official record
Conditions
Microvesicle Particles, Thermal Burn
Interventions
Amitriptyline, Placebo
Drug
Lead sponsor
Wright State University
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2033
U.S. locations
1
States / cities
Fairborn, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Jul 21, 2026, 6:08 PM EDT
Recruiting Phase 3 Interventional

Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Burn Wounds as an Alternative to Autografting

NCT06223269
View directory record Official record
Conditions
Burns Degree Third, Burn (Disorder), Burn Degree Second, Thermal Burn, Wound Heal
Interventions
Skin Xenotransplant, Autograft(ing)
Drug · Procedure
Lead sponsor
XenoTherapeutics, Inc.
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Phoenix, Arizona • Augusta, Georgia • Portland, Maine + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Jul 21, 2026, 6:08 PM EDT
Completed Not applicable Interventional

The Effects of Viscoelastometry Guided Resuscitation During Burn Excision on Post Resuscitation Infections

NCT03730415
View directory record Official record
Conditions
Burns
Interventions
Viscoelastic (VE) Guided Transfusion
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Jul 21, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Brief Thermal and Electrical Pain (Four Study Days)

NCT00682682
View directory record Official record
Conditions
Pain
Interventions
Virtual Reality video distraction, Virtual Reality video game
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 12, 2011 · Synced Jul 21, 2026, 6:08 PM EDT
Completed No phase listed Observational

Burn Validation Study

NCT06131203
View directory record Official record
Conditions
Burns, Wound Heal, Wounds and Injuries
Interventions
DeepView SnapShot Portable (DV-SSP)
Device
Lead sponsor
SpectralMD
Industry
Eligibility
Not listed
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
21
States / cities
Phoenix, Arizona • Sacramento, California • San Diego, California + 17 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Jul 21, 2026, 6:08 PM EDT
Terminated Not applicable Interventional Results available

Single-Stage Integra Reconstruction in Burns

NCT03077087
View directory record Official record
Conditions
Thermal Burn
Interventions
thin Integra® (125 cm2)
Device
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 125 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 13, 2023 · Synced Jul 21, 2026, 6:08 PM EDT
Recruiting Phase 2 Interventional

Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns

NCT01297400
View directory record Official record
Conditions
Burns
Interventions
Investigational Drug, MW-III, Silvadene® Cream 1% [Silver Sulfadiazine]
Drug
Lead sponsor
Skingenix, Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Phoenix, Arizona • Sacramento, California • Washington D.C., District of Columbia + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Jul 21, 2026, 6:08 PM EDT
Suspended Phase 3 Interventional

VItamin C in Thermal injuRY: The VICToRY Trial

NCT04138394
View directory record Official record
Conditions
Shock, Thermal Burn
Interventions
Ascorbic Acid, placebo
Drug
Lead sponsor
Clinical Evaluation Research Unit at Kingston General Hospital
Other
Eligibility
18 Years and older
Enrollment
666 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
10
States / cities
Phoenix, Arizona • Bridgeport, Connecticut • Washington D.C., District of Columbia + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Jul 21, 2026, 6:08 PM EDT
Completed Phase 4 Interventional Results available

Continuous Lidocaine Infusion for Management of Perioperative Burn Pain

NCT02059902
View directory record Official record
Conditions
Thermal Burns
Interventions
Lidocaine, Placebo
Drug · Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Jul 21, 2026, 6:08 PM EDT
Completed Not applicable Interventional

Study of Low Adherent Dressing Versus the Standard of Care for the Management of Skin Grafts Over Thermal Burns

NCT01654094
View directory record Official record
Conditions
Burns, Skin Burn Requiring Skin Graft
Interventions
P6 Low Adherent Dressing, Standard of Care (SOC)
Device · Other
Lead sponsor
Milliken Healthcare Products, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
4
States / cities
Gainesville, Florida • Chapel Hill, North Carolina • Winston-Salem, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2017 · Synced Jul 21, 2026, 6:08 PM EDT
Not yet recruiting Phase 3 Interventional

Plasma Resuscitation Early for Evaluating Volume and Endotheliopathy of Thermal Injury (PREEVEnT) Trial

NCT07212998
View directory record Official record
Conditions
Burn Injury, Thermal Burn
Interventions
Plasma, Standard care
Biological
Lead sponsor
Jason Sperry
Other
Eligibility
18 Years to 75 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 21, 2026, 6:08 PM EDT
Suspended Not applicable Interventional

Safety and Feasibility of ADRCs Treatment To Patients With Thermal Wounds

NCT03435172
View directory record Official record
Conditions
Thermal Burn
Interventions
Device-ADRCs intravenously infusion
Device
Lead sponsor
Cytori Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
5
States / cities
Phoenix, Arizona • Los Angeles, California • Washington D.C., District of Columbia + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Jul 21, 2026, 6:08 PM EDT
Not listed Phase 2 Interventional

Efficacy of R-Pdf/Gbb in Healing Wounds Caused by Third Degree Thermal and Electrical Burns

NCT00812513
View directory record Official record
Conditions
Burns, Electric Burns
Interventions
R-Pdf/Gbb 0.01% gel
Drug
Lead sponsor
American Scitech International
Other
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Livingston, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 19, 2011 · Synced Jul 21, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study in the Use of Virtual Reality as an Adjunct to Pain Control in Burn Patients

NCT00591448
View directory record Official record
Conditions
Burn
Interventions
Virtual Reality (VR)
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
6 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 16, 2012 · Synced Jul 21, 2026, 6:08 PM EDT
Not listed Not applicable Interventional

Evaluation of the Effectiveness of PermeaDerm® (PD) as Compared to Mepilex Ag®

NCT05084183
View directory record Official record
Conditions
Thermal Burn
Interventions
PermeaDerm®, Mepilex Ag
Device
Lead sponsor
Stedical Scientific, Inc.
Industry
Eligibility
Up to 75 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2022 · Synced Jul 21, 2026, 6:08 PM EDT
Terminated Phase 2 Interventional Results available

Vitamin D and n-3 Polyunsaturated Fatty Acids (PUFAs) to Prevent Chronic Pain Following Major Thermal Burn Injury

NCT03313076
View directory record Official record
Conditions
Chronic Pain Following Thermal Burn Injury
Interventions
Omega-3 fatty acids (fish oil), Vitamin D3 (cholecalciferol), Vitamin D3 (cholecalciferol) placebo, Omega-3 fatty acid placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jul 21, 2026, 6:08 PM EDT
Not listed Not applicable Interventional

Safety Study of a Novel Wearable Phototherapy System for the Management of Acute Burn Wounds

NCT03948360
View directory record Official record
Conditions
Burn Wound
Interventions
Low-Irradiance Monochromatic Biostimulation (LIMB) Device, Standard of Care
Device · Other
Lead sponsor
Rogers Sciences Inc.
Industry
Eligibility
Up to 21 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 12, 2019 · Synced Jul 21, 2026, 6:08 PM EDT
Withdrawn Phase 4 Interventional

A Randomized, Double-Blind Study of Placebo vs. Ketamine For Use During Dressing Changes in Critically Ill Burn Patients

NCT02336308
View directory record Official record
Conditions
Thermal Hyperalgesia, Anxiety, Pain
Interventions
Ketamine, Placebo, Normal Saline
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 25, 2015 · Synced Jul 21, 2026, 6:08 PM EDT
Withdrawn Phase 2 Interventional

Pilot Study to Compare Topical Voriconazole to Placebo as a Pain Reducing Agent

NCT02689713
View directory record Official record
Conditions
Pain, Thermal Injury, Burns, Hyperalgesia
Interventions
Voriconazole (topical), Topical Sterile Water Placebo Group
Drug
Lead sponsor
Kenneth Hargreaves
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 16, 2018 · Synced Jul 21, 2026, 6:08 PM EDT
Approved For Marketing No phase listed Expanded access

Use of NexoBrid for Treatment of Acute Deep Partial and Full Thickness Burn Injuries

NCT04040660
View directory record Official record
Conditions
Thermal Burn
Interventions
NexoBrid
Drug
Lead sponsor
MediWound Ltd
Industry
Eligibility
0 Years and older
U.S. locations
28
States / cities
Mobile, Alabama • Phoenix, Arizona • Orange, California + 23 more
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Jul 21, 2026, 6:08 PM EDT