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ClinicalTrials.gov public records Last synced Sep 9, 2026, 7:34 PM EDT

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Showing 1–24 of 40 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Thoracic Aortic Dissection Clear all
Recruiting No phase listed Observational

PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

NCT04545502
View directory record Official record
Conditions
Aneurysm, Dissection, Aortic Root Aneurysm, Aortic Root Dissection, Carotid Artery Injuries, Aortic Arch, Bypass Extremity Graft, Occlusive Vascular Disease, Aortic Diseases
Interventions
Gelsoft Plus Vascular Graft, Vascular Bypass Graft, Cardiovascular Patch, Gelweave Vascular Graft, Gelweave Valsalva Vascular Graft
Device
Lead sponsor
Vascutek Ltd.
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2037
U.S. locations
10
States / cities
Aurora, Colorado • Tampa, Florida • Indianapolis, Indiana + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 9, 2026, 7:34 PM EDT
Recruiting Not applicable Interventional

Endovascular Treatment of TAAA and Aortic Arch Aneurysms Using Fenestrated and Branched Stent Grafts

NCT02323581
View directory record Official record
Conditions
Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Thoracic, Aortic Dissection, Thoracoabdominal
Interventions
Endovascular treatment of Thoracoabdominal Aortic Aneurysm, Endovascular treatment of Aortic Arch Aneurysms
Device
Lead sponsor
Darren Schneider, M.D.
Other
Eligibility
18 Years and older
Enrollment
520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2033
U.S. locations
2
States / cities
New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 9, 2026, 7:34 PM EDT
Recruiting Not applicable Interventional

NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness

NCT04471909
View directory record Official record
Conditions
Aortic Dissection, Aortic Aneurysm, Intramural Hematoma, Penetrating Aortic Ulcer
Interventions
NEXUS Aortic Stent Graft System
Device
Lead sponsor
Endospan Ltd.
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
31
States / cities
Birmingham, Alabama • La Jolla, California • Sacramento, California + 27 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 9, 2026, 7:34 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the GORE Conformable TAG® Thoracic Endoprosthesis for Treatment of Acute Complicated Type B Aortic Dissection

NCT00908388
View directory record Official record
Conditions
Type B Aortic Dissection
Interventions
GORE TAG® Thoracic Endoprosthesis
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
37
States / cities
Birmingham, Alabama • Los Angeles, California • San Francisco, California + 31 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Sep 9, 2026, 7:34 PM EDT
Completed Not applicable Interventional

Thoraflex™ Hybrid IDE Study

NCT02724072
View directory record Official record
Conditions
Aortic Aneurysm, Aortic Dissection, Aortic Rupture
Interventions
Thoraflex™ Hybrid Device
Device
Lead sponsor
Bolton Medical
Industry
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
12
States / cities
Palo Alto, California • Atlanta, Georgia • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated May 15, 2022 · Synced Sep 9, 2026, 7:34 PM EDT
Recruiting Not applicable Interventional

GORE® TAG® Thoracic Branch Endoprosthesis Zone 0/1 Post-Approval Study

NCT07166133
View directory record Official record
Conditions
Aortic Arch Dissection, Aortic Arch Aneurysm
Interventions
GORE® TAG® Thoracic Branch Endoprosthesis
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2036
U.S. locations
16
States / cities
Scottsdale, Arizona • Los Angeles, California • Hartford, Connecticut + 13 more
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 9, 2026, 7:34 PM EDT
Recruiting Not applicable Interventional

Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made Devices

NCT02050113
View directory record Official record
Conditions
Complex Aortic Aneurysms, Thoracoabdominal Aneurysms, Pararenal Aneurysms, Juxtarenal Aneurysms, Marfan Syndrome, Ehlers-Danlos Syndrome, Loeys-Dietz Syndrome, Aortic Arch Aneurysm
Interventions
Custom Made Fenestrated or Branched Stent Graft
Device
Lead sponsor
Andres Schanzer
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2030
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 9, 2026, 7:34 PM EDT
Active, not recruiting Not applicable Interventional

Study of the RelayPro Thoracic Stent-Graft in Subjects With an Acute, Complicated Type B Aortic Dissection

NCT03033043
View directory record Official record
Conditions
Aortic Dissection Type B
Interventions
Relay Pro Stent-Graft
Device
Lead sponsor
Bolton Medical
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
21
States / cities
Los Angeles, California • Aurora, Colorado • Hartford, Connecticut + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Sep 9, 2026, 7:34 PM EDT
Completed Not applicable Interventional Results available

Zenith® Dissection Clinical Trial

NCT01568320
View directory record Official record
Conditions
Aortic Dissection
Interventions
Endovascular Treatment (Zenith)
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
23
States / cities
Los Angeles, California • Gainesville, Florida • Tampa, Florida + 18 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2021 · Synced Sep 9, 2026, 7:34 PM EDT
Completed Not applicable Interventional Results available

Zenith® Dissection Endovascular System

NCT02094300
View directory record Official record
Conditions
Aortic Dissection
Interventions
Zenith® Dissection Endovascular Graft
Device
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
5
States / cities
Gainesville, Florida • Boston, Massachusetts • Camden, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Sep 9, 2026, 7:34 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes

NCT02213484
View directory record Official record
Conditions
Marfan Syndrome, Loeys-Dietz Syndrome, Thoracic Aortic Aneurysm and Dissection Syndromes, Ehlers-Danlos Type IV Syndrome, Turner Syndrome
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Days to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 14, 2017 · Synced Sep 9, 2026, 7:34 PM EDT
Active, not recruiting Not applicable Interventional

Visceral Manifold and Unitary Device Study for the Repair of Thoracoabdominal Aortic Aneurysms

NCT02294435
View directory record Official record
Conditions
Thoracoabdominal Aneurysms
Interventions
Visceral Manifold and Thoracic Bifurcation, Unitary Manifold
Device
Lead sponsor
Sanford Health
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2029
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Dec 15, 2024 · Synced Sep 9, 2026, 7:34 PM EDT
Active, not recruiting No phase listed Observational

Post Market Clinical Follow-Up Study in Patients Treated With the On-X Ascending Aortic Prosthesis (AAP)

NCT05082454
View directory record Official record
Conditions
Aortic Valve Disease
Interventions
Open repair
Device
Lead sponsor
JOTEC GmbH
Industry
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
3
States / cities
Danville, Pennsylvania • Houston, Texas • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Sep 9, 2026, 7:34 PM EDT
Not listed Not applicable Interventional

Trial of Exercise in Aortic Dissection Survivors

NCT05610462
View directory record Official record
Conditions
Thoracic Aortic Dissection
Interventions
Guided Exercise Training Program, Usual Care
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
3
States / cities
Ann Arbor, Michigan • St Louis, Missouri • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Sep 9, 2026, 7:34 PM EDT
Active, not recruiting No phase listed Observational

Pathogenetic Basis of Aortopathy and Aortic Valve Disease

NCT03440697
View directory record Official record
Conditions
Aortopathies, Thoracic Aortic Aneurysm, Aortic Valve Disease, Thoracic Aortic Disease, Thoracic Aortic Dissection, Thoracic Aortic Rupture, Ascending Aortic Disease, Descending Aortic Disease, Ascending Aortic Aneurysm, Descending Aortic Aneurysm, Marfan Syndrome, Loeys-Dietz Syndrome, Vascular Ehlers-Danlos Syndrome, Shprintzen-Goldberg Syndrome, Turner Syndrome, PHACE Syndrome, Autosomal Recessive Cutis Laxa, Congenital Contractural Arachnodactyly, Arterial Tortuosity Syndrome, Bicuspid Aortic Valve-Associated Aortopathy, Bicuspid Aortic Valve, Familial Thoracic Aortic Aneurysm and Aortic Dissection
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
Not listed
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2030
U.S. locations
2
States / cities
Atlanta, Georgia • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 9, 2026, 7:34 PM EDT
Completed No phase listed Observational

Diagnostic Accuracy of Multislice CT Angiography for Acute Chest Pain

NCT00855231
View directory record Official record
Conditions
Chest Pain, Acute Coronary Syndrome, Pulmonary Embolism, Aortic Dissection
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
30 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 26, 2017 · Synced Sep 9, 2026, 7:34 PM EDT
Enrolling by invitation Not applicable Interventional

Evaluation of the GORE® Ascending Stent Graft

NCT05800743
View directory record Official record
Conditions
Aortic Aneurysm, Thoracic, Pseudoaneurysm, Aortic Dissection, Aorta; Lesion
Interventions
GORE® Ascending Stent Graft (ASG device), GORE® Thoracic Aortic Graft Thoracic Branch Endoprosthesis (TBE Device), Surgery
Device · Procedure
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
370 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2034
U.S. locations
41
States / cities
Birmingham, Alabama • Long Beach, California • Los Angeles, California + 37 more
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 9, 2026, 7:34 PM EDT
Recruiting Phase 1 Interventional

Nicotinamide Riboside (NR) to Treat Moyamoya-like Cerebrovascular Disease in Smooth Muscle Dysfunction Syndrome (SMDS)

NCT06280482
View directory record Official record
Conditions
Smooth Muscle Dysfunction Syndrome (SMDS)
Interventions
Nicotinamide riboside (NR)
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
1 Year and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Sep 9, 2026, 7:34 PM EDT
Active, not recruiting No phase listed Observational

Cerebral Hemodynamics and Microemboli During Placement of Relay®Branch Thoracic Stent-Graft System

NCT05155956
View directory record Official record
Conditions
Thoracic Aortic Aneurysm, Thoracic Aortic Dissection, Microemboli
Interventions
transcranial Doppler ultrasonography (TCD)
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 9, 2026, 7:34 PM EDT
Recruiting No phase listed Observational

Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

NCT06658730
View directory record Official record
Conditions
Vascular Disease, Dissection, Dissection Aortic Aneurysm, Dissection of Aorta, Aneurysm Thoracic, Aneurysm Dissecting, Transection Aorta, Intramural Hematoma
Interventions
Endovascular
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2038
U.S. locations
24
States / cities
Tucson, Arizona • Los Angeles, California • Stanford, California + 19 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 9, 2026, 7:34 PM EDT
Recruiting Not applicable Interventional

A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

NCT07078383
View directory record Official record
Conditions
Aortic Aneurysm, Aortic Aneurysm and Dissection, Aortic Diseases, Aneurysm of Aorta, Thoracic, Aneurysmal Disease, Aorta, Thoracic Pathologies
Interventions
Rapidlink
Device
Lead sponsor
Vascutek Ltd.
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
15
States / cities
Los Angeles, California • Aurora, Colorado • Washington D.C., District of Columbia + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 9, 2026, 7:34 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease

NCT04005976
View directory record Official record
Conditions
Aortic Aneurysm, Aortic Dissection, Aortic Diseases
Interventions
Not listed
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Not listed
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2037
U.S. locations
14
States / cities
Newport Beach, California • Sacramento, California • Lexington, Kentucky + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Sep 9, 2026, 7:34 PM EDT
Terminated Not applicable Interventional Results available

Feasibility of Endovascular Repair of Ascending Aortic Pathologies

NCT03322033
View directory record Official record
Conditions
Dissection of Thoracic Aorta
Interventions
Valiant PS-IDE Stent Graft
Device
Lead sponsor
Baylor Research Institute
Other
Eligibility
21 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 9, 2026, 7:34 PM EDT
Completed Not applicable Interventional Results available

Physician-Sponsored IDE for the Talent Endoluminal Stent Graft System for the Treatment of Thoracic Lesions

NCT00597870
View directory record Official record
Conditions
Thoracic Aortic Aneurysms, Thoracic Transections, Intramural Hematoma, Pseudoaneurysm, Thoracic Aortic Dissection
Interventions
Endoluminal treament of thoracic lesions
Device
Lead sponsor
Rodney A. White, M.D.
Other
Eligibility
18 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2021
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Sep 9, 2026, 7:34 PM EDT