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ClinicalTrials.gov public records Last synced Nov 6, 2026, 5:14 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 41 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Thoracic Aortic Dissection Clear all

Conditions: Aortic Dissection, Aortic Aneurysm, Intramural Hematoma, Penetrating Aortic Ulcer
Interventions: NEXUS Aortic Stent Graft System; Device
Lead sponsor: Endospan Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2029
U.S. locations: 31
States / cities: Birmingham, Alabama • La Jolla, California • Sacramento, California + 27 more

Conditions: Thoracic Aortic Aneurysm, Penetrating Aortic Ulcers (PAUs), Thoracic Aortic Dissection, Pseudoaneurysm
Interventions: GORE® Multibranch Arch Endoprosthesis, GORE® Ascending Stent Graft; Device
Lead sponsor: W.L.Gore & Associates; Industry
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2033
U.S. locations: 3
States / cities: Los Angeles, California • Cleveland, Ohio • Plano, Texas

Conditions: Aortic Aneurysm, Thoracic, Chronic Type B Dissection
Interventions: Valiant Mona LSA Thoracic Stent Graft System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2024
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Aortic Aneurysm, Aortic Dissection, Bicuspid Aortic Valve (BAV), Heart Failure, Cardiovascular Diseases
Interventions: Not listed
Lead sponsor: University of Michigan; Other
Eligibility: Not listed
Enrollment: 15,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2053
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Vascular Disease, Dissection, Dissection Aortic Aneurysm, Dissection of Aorta, Aneurysm Thoracic, Aneurysm Dissecting, Transection Aorta, Intramural Hematoma
Interventions: Endovascular; Device
Lead sponsor: W.L.Gore & Associates; Industry
Eligibility: 18 Years and older
Enrollment: 1,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2038
U.S. locations: 24
States / cities: Tucson, Arizona • Los Angeles, California • Stanford, California + 19 more

Conditions: Marfan Syndrome
Interventions: Losartan Potassium, Atenolol; Drug
Lead sponsor: Carelon Research; Other
Eligibility: 6 Months to 25 Years
Enrollment: 608 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2014
U.S. locations: 24
States / cities: Los Angeles, California • Palo Alto, California • San Diego, California + 18 more

Conditions: Thoracic Aortic Aneurysm, Thoracic Aortic Dissection, Microemboli
Interventions: transcranial Doppler ultrasonography (TCD); Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Thoracic Aortic Dissection
Interventions: Valiant Navion Thoracic Stent Graft System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 102 participants
Timeline: 2020 – 2024
U.S. locations: 12
States / cities: Birmingham, Alabama • Gainesville, Florida • Atlanta, Georgia + 9 more

Conditions: Aortic Dissection
Interventions: Valiant Thoracic Stent Graft with the Captivia Delivery System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2017
U.S. locations: 17
States / cities: Los Angeles, California • Torrance, California • Washington D.C., District of Columbia + 11 more

Conditions: Thoracic Aortic Aneurysms, Dissecting, Aneurysm, Ascending Aorta Aneurysm, Aortic Arch; Aneurysm, Dissecting, Ascending Aortic Dissection, Thoracoabdominal Aortic Aneurysm, Renal Artery Aneurysm, Superior Mesenteric Artery Aneurysm, Aortic Dissection
Interventions: Endovascular stent-graft implantation; Device
Lead sponsor: Matthew Eagleton; Other
Eligibility: 18 Years and older
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2030
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Marfan Syndrome, Turner Syndrome, Ehlers-Danlos Syndrome, Loeys-Dietz Syndrome, FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation, Bicuspid Aortic Valve Without Known Family History, Bicuspid Aortic Valve With Family History, Bicuspid Aortic Valve With Coarctation, Familial Thoracic Aortic Aneurysm and Dissections, Shprintzen-Goldberg Syndrome, Other Aneur/Diss of Thoracic Aorta Not Due to Trauma, <50yo, Other Congenital Heart Disease
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: Not listed
Enrollment: 3,706 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2016
U.S. locations: 7
States / cities: Honolulu, Hawaii • Baltimore, Maryland • New York, New York + 3 more

Conditions: Thoracoabdominal Aneurysms
Interventions: Visceral Manifold and Thoracic Bifurcation, Unitary Manifold; Device
Lead sponsor: Sanford Health; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2029
U.S. locations: 1
States / cities: Sioux Falls, South Dakota

Conditions: Thoracic Diseases, Aortic Aneurysm, Aortic Dissection, Thoracic Aortic Aneurysm, Thoracic Aortic Dissection
Interventions: Thoraflex Hybrid, RelayPro NBS; Device
Lead sponsor: Vascutek Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 352 participants
Timeline: 2023 – 2036
U.S. locations: 18
States / cities: Birmingham, Alabama • Los Angeles, California • Aurora, Colorado + 14 more

Conditions: Aortic Arch Dissection, Aortic Arch Aneurysm
Interventions: GORE® TAG® Thoracic Branch Endoprosthesis; Device
Lead sponsor: W.L.Gore & Associates; Industry
Eligibility: 18 Years and older
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2036
U.S. locations: 24
States / cities: Scottsdale, Arizona • Los Angeles, California • Palo Alto, California + 19 more

Conditions: Dissection of Thoracic Aorta
Interventions: Valiant PS-IDE Stent Graft; Device
Lead sponsor: Baylor Research Institute; Other
Eligibility: 21 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Plano, Texas

Conditions: Aortic Aneurysm, Aortic Aneurysm and Dissection, Aortic Diseases, Aneurysm of Aorta, Thoracic, Aneurysmal Disease, Aorta, Thoracic Pathologies
Interventions: Rapidlink; Device
Lead sponsor: Vascutek Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 15
States / cities: Los Angeles, California • Aurora, Colorado • Washington D.C., District of Columbia + 11 more

Conditions: Thoracic Aortic Aneurysms, Thoracic Transections, Intramural Hematoma, Pseudoaneurysm, Thoracic Aortic Dissection
Interventions: Endoluminal treament of thoracic lesions; Device
Lead sponsor: Rodney A. White, M.D.; Other
Eligibility: 18 Years and older
Enrollment: 304 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2021
U.S. locations: 1
States / cities: Torrance, California

Conditions: Juxtarenal Aortic Aneurysm, Suprarenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Penetrating Aortic Ulcer, Aortic Arch Aneurysm, Aortic Dissection
Interventions: Cook Custom Aortic Endograft, Zenith t-Branch Endovascular Graft, Surgeon-Modified Endograft; Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 410 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2027
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Complex Aortic Aneurysms, Thoracoabdominal Aneurysms, Pararenal Aneurysms, Juxtarenal Aneurysms, Marfan Syndrome, Ehlers-Danlos Syndrome, Loeys-Dietz Syndrome, Aortic Arch Aneurysm
Interventions: Custom Made Fenestrated or Branched Stent Graft; Device
Lead sponsor: Andres Schanzer; Other
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2030
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Thoracic, Aortic Dissection, Thoracoabdominal
Interventions: Endovascular treatment of Thoracoabdominal Aortic Aneurysm, Endovascular treatment of Aortic Arch Aneurysms; Device
Lead sponsor: Darren Schneider, M.D.; Other
Eligibility: 18 Years and older
Enrollment: 520 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2033
U.S. locations: 2
States / cities: New York, New York • Philadelphia, Pennsylvania

Conditions: Aortic Arch Aneurysm, Aortic Arch Dissection, Chronic Aortic Dissection, Acute Aortic Dissection
Interventions: Arcevo™ LSA Hybrid Stent Graft System; Device
Lead sponsor: Artivion Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2032
U.S. locations: 22
States / cities: Birmingham, Alabama • Los Angeles, California • Aurora, Colorado + 16 more

Conditions: Aortic Aneurysm, Thoracic, Aortic Dissection
Interventions: Not listed
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 97 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Aortic Valve Disease
Interventions: Open repair; Device
Lead sponsor: JOTEC GmbH; Industry
Eligibility: 18 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2029
U.S. locations: 3
States / cities: Danville, Pennsylvania • Houston, Texas • Richmond, Virginia

Conditions: Aortic Dissection, Intramural Hematoma, Penetrating Ulcer, Pseudoaneurysm
Interventions: Endovascular repair with Valiant PS-IDE Stent Graft; Device
Lead sponsor: Rodney A. White, MD; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2033
U.S. locations: 3
States / cities: Long Beach, California • Los Angeles, California • Torrance, California

Search by objective public record fields.

NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness

MBA Early Feasibility Study

Evaluation of the Valiant Mona LSA Thoracic Stent Graft System in Descending TAA and Chronic Dissections

Cardiovascular Health Improvement Project

Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome

Cerebral Hemodynamics and Microemboli During Placement of Relay®Branch Thoracic Stent-Graft System

DISSECT-N Post Market Data Collection Registry

Study to Evaluate the Clinical Performance of the Valiant Thoracic Stent Graft With the Captivia Delivery System (Valiant Captivia) for the Treatment of Acute, Complicated Type B Aortic Dissections

Endovascular Treatment of Thoracic Aortic Disease

National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions

Visceral Manifold and Unitary Device Study for the Repair of Thoracoabdominal Aortic Aneurysms

Thoraflex Hybrid and Relay Extension Post-Approval Study

GORE® TAG® Thoracic Branch Endoprosthesis Zone 0/1 Post-Approval Study

Feasibility of Endovascular Repair of Ascending Aortic Pathologies

A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

Physician-Sponsored IDE for the Talent Endoluminal Stent Graft System for the Treatment of Thoracic Lesions

Evaluation of the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and Surgeon-Modified Endograft in Treating Aortic Pathologies

Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made Devices

Endovascular Treatment of TAAA and Aortic Arch Aneurysms Using Fenestrated and Branched Stent Grafts

Clinical Study to Evaluate the Safety and Effectiveness of Arcevo LSA

Point-of-Care Focused Cardiac Ultrasound in Assessing the Thoracic Aorta

Post Market Clinical Follow-Up Study in Patients Treated With the On-X Ascending Aortic Prosthesis (AAP)

Feasibility of Endovascular Repair Of Ascending Aortic Pathologies