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ClinicalTrials.gov public records Last synced Sep 8, 2026, 5:56 PM EDT

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Showing 1–24 of 194 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Thoracic Injury Clear all
Completed No phase listed Observational

Chest Wall Repair of Rib Fractures After Trauma

NCT00926991
View directory record Official record
Conditions
Rib Fractures
Interventions
No intervention
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 21, 2011 · Synced Sep 8, 2026, 5:56 PM EDT
Recruiting Not applicable Interventional

Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates

NCT06849596
View directory record Official record
Conditions
Neonatal Resuscitation, Apnea Neonatal
Interventions
Ventilator derived positive pressure ventilation - V-PPV, T-piece resuscitator (TPR)
Device
Lead sponsor
Michelle Baczynski
Other
Eligibility
25 Weeks to 29 Weeks
Enrollment
780 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 8, 2026, 5:56 PM EDT
Enrolling by invitation Not applicable Interventional

Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Pain Following Thoracic Trauma

NCT06069154
View directory record Official record
Conditions
Rib Fracture, Rib Fracture Multiple
Interventions
Cryoneurolysis, Local anesthetic peripheral nerve block, Sham Cryoneurolysis, Sham peripheral nerve block
Device · Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
5
States / cities
La Jolla, California • Bethesda, Maryland • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 8, 2026, 5:56 PM EDT
Completed Not applicable Interventional Results available

Zenith® Dissection Endovascular System

NCT02094300
View directory record Official record
Conditions
Aortic Dissection
Interventions
Zenith® Dissection Endovascular Graft
Device
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
5
States / cities
Gainesville, Florida • Boston, Massachusetts • Camden, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Sep 8, 2026, 5:56 PM EDT
Completed Not applicable Interventional Results available

Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)

NCT04283994
View directory record Official record
Conditions
Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasms, Pulmonary Disease, Chronic Obstructive, Heart Failure, Congestive, Liver Cirrhosis, Kidney Failure, Chronic, Lung Diseases, Interstitial, Peripheral Vascular Disease, Diabetes With End Organ Injury
Interventions
Survey-based Patient/Clinician Jumpstart, EHR-based Clinician Jumpstart
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
756 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 23, 2025 · Synced Sep 8, 2026, 5:56 PM EDT
Completed Not applicable Interventional Results available

TRANSFIX Zenith® Transection Clinical Study

NCT01688050
View directory record Official record
Conditions
Thoracic Aorta, Thoracic Injuries, Blunt Injuries
Interventions
Zenith® TX2® Low Profile Endovascular Graft
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
16 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
21
States / cities
Little Rock, Arkansas • Los Angeles, California • Miami, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Sep 8, 2026, 5:56 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Longitudinal MR Imaging of Pulmonary Function in Patients Receiving Thoracic Radiation Treatment

NCT02478255
View directory record Official record
Conditions
Radiation Injury
Interventions
Hyperpolarized 129-Xenon gas, MRI
Drug · Device
Lead sponsor
Bastiaan Driehuys
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Sep 8, 2026, 5:56 PM EDT
Terminated Phase 1 Interventional

Flaxseed Supplement in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Undergoing Chemotherapy and Radiation Therapy

NCT00955942
View directory record Official record
Conditions
Lung Cancer, Radiation Toxicity
Interventions
flaxseed, placebo
Dietary Supplement · Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years to 120 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 1, 2020 · Synced Sep 8, 2026, 5:56 PM EDT
Completed No phase listed Observational

The CAROLE (CArdiac Related Oncologic Late Effects) Study

NCT03235427
View directory record Official record
Conditions
Coronary Artery Disease, Cardiac Disease, Cardiac Toxicity, Radiation, Radiation Therapy, Atherosclerotic Heart Disease, Cardiotoxicity, Breast Cancer, Lung Cancer, Lymphoma, Cancer, Carcinoma, Intraductal, Noninfiltrating
Interventions
Not listed
Lead sponsor
Northwell Health
Other
Eligibility
26 Years to 78 Years · Female only
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lake Success, New York
Source: ClinicalTrials.gov public record
Updated May 20, 2019 · Synced Sep 8, 2026, 5:56 PM EDT
Completed Phase 4 Interventional Results available

Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach

NCT02135146
View directory record Official record
Conditions
Hypotension, Kidney Injury
Interventions
Plasmalyte 3ml/kg/hr group, Plasmalyte 6ml/kg/hr group
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 2, 2020 · Synced Sep 8, 2026, 5:56 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

MnSOD (Esophageal Protectant) to Prevent Esophagitis During Radiation/Chemotherapy Treatment for Non-Small Cell Lung Cancer (NSCLC)

NCT00618917
View directory record Official record
Conditions
Esophageal, Toxicity
Interventions
Manganese Superoxide Dismutase Plasmid Liposome, carboplatin, paclitaxel, Radiation Therapy
Genetic · Drug · Radiation
Lead sponsor
Joel Greenberger
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 11, 2021 · Synced Sep 8, 2026, 5:56 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study of Effects of Age and Hyperkyphosis on Spine Motion and Loading

NCT03008902
View directory record Official record
Conditions
Kyphosis, Vertebral Fracture
Interventions
Near-infrared passive motion capture recording
Procedure
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Sep 8, 2026, 5:56 PM EDT
Completed No phase listed Observational

Collecting Interval Timed Incisional Epidermal and Dermal Tissue Samples During Surgical Procedures to Profile Temporal Response of Tissue After Noxious Stimuli

NCT04224870
View directory record Official record
Conditions
Abdominal Surgery, Thoracic Surgery, Urological Surgery
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 8, 2026, 5:56 PM EDT
Recruiting No phase listed Observational

PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

NCT04545502
View directory record Official record
Conditions
Aneurysm, Dissection, Aortic Root Aneurysm, Aortic Root Dissection, Carotid Artery Injuries, Aortic Arch, Bypass Extremity Graft, Occlusive Vascular Disease, Aortic Diseases
Interventions
Gelsoft Plus Vascular Graft, Vascular Bypass Graft, Cardiovascular Patch, Gelweave Vascular Graft, Gelweave Valsalva Vascular Graft
Device
Lead sponsor
Vascutek Ltd.
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2037
U.S. locations
10
States / cities
Aurora, Colorado • Tampa, Florida • Indianapolis, Indiana + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 8, 2026, 5:56 PM EDT
Completed Not applicable Interventional Results available

Surgical Stabilization for Rib Fractures

NCT04081233
View directory record Official record
Conditions
Trauma Chest, Rib Fracture Multiple
Interventions
surgical stabilization, Usual care
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
16 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 1, 2024 · Synced Sep 8, 2026, 5:56 PM EDT
Withdrawn Not applicable Interventional

Paradoxical Response to Chest Wall Loading in Mechanically Ventilated Patients

NCT06093958
View directory record Official record
Conditions
ARDS, COVID-19, Mechanical Ventilation Pressure High, Ventilator-Induced Lung Injury
Interventions
Manual loading of the chest wall
Diagnostic Test
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 6, 2024 · Synced Sep 8, 2026, 5:56 PM EDT
Terminated Phase 2 Interventional Results available

Efficacy and Safety of RMC-035 in Subjects at High Risk for Acute Kidney Injury Following Open-Chest Cardiac Surgery

NCT05126303
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
RMC-035, Placebo
Drug
Lead sponsor
Guard Therapeutics AB
Industry
Eligibility
18 Years to 84 Years
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
8
States / cities
Fort Wayne, Indiana • Lincoln, Nebraska • Rochester, New York + 5 more
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Sep 8, 2026, 5:56 PM EDT
Completed No phase listed Observational

Role of Toxins in Lung Infections Caused by Pseudomonas Aeruginosa

NCT00027183
View directory record Official record
Conditions
Pseudomonas Infection, Cystic Fibrosis
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
9 Years to 99 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 5, 2022 · Synced Sep 8, 2026, 5:56 PM EDT
Withdrawn No phase listed Observational

Operative Versus Non-Operative Treatment of Clavicle Fracture in PolyTrauma

NCT01133769
View directory record Official record
Conditions
Clavicle Fracture, Chest Injury
Interventions
Not listed
Lead sponsor
Anna Rockich
Other
Eligibility
18 Years to 79 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced Sep 8, 2026, 5:56 PM EDT
Completed Not applicable Interventional

Suction Versus Water Seal for Initial Treatment of Traumatic Pneumothorax Trial

NCT06688734
View directory record Official record
Conditions
Pneumothorax, Trauma
Interventions
Inital water seal, Initial suction
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 4, 2025 · Synced Sep 8, 2026, 5:56 PM EDT
Terminated No phase listed Observational

Radiation Induced Cardiopulmonary Injury in Humans

NCT02259452
View directory record Official record
Conditions
Thoracic, Pulmonary Injury, Heart Injuries
Interventions
SPECT Lung Perfusion Scan, SPECT Heart Perfusion Scan, Pulmonary Function Tests
Procedure
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 25, 2020 · Synced Sep 8, 2026, 5:56 PM EDT
Completed No phase listed Observational

Pharmacologic Impact on Sedation Assessments

NCT01105663
View directory record Official record
Conditions
Pediatric Acute Lung Injury
Interventions
Pharmacokinetic Sampling and pharmacogenetic analysis
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Year to 17 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 26, 2017 · Synced Sep 8, 2026, 5:56 PM EDT
Recruiting Not applicable Interventional

Non-Invasive Interventions for Respiratory Recovery in Chronic Spinal Cord Injury

NCT07135583
View directory record Official record
Conditions
Spinal Cord Injury, Chronic, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic, Incomplete Spinal Cord Injury
Interventions
Active Comparator: Single Intervention 1, Active Comparator: Single Intervention 2, Respiratory Resistance Exercise
Other · Behavioral
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 8, 2026, 5:56 PM EDT
Terminated No phase listed Observational

Cardiac MRI Biomarker Testing (GCC 1618)

NCT02688166
View directory record Official record
Conditions
Breast Cancer, Lung Cancer (Non-Small Cell), Thoracic Cancer, Thymic Cancer, Mesothelioma
Interventions
Complete Cardiac Magnetic Resonance Imaging (MRI)
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 12, 2022 · Synced Sep 8, 2026, 5:56 PM EDT