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Showing 1–24 of 114 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Results available

Preoperative Gabapentin for Post-tonsillectomy Pain in Children

NCT01707420
Conditions
Post Operative Pain Management in Children With Tonsillectomy/Adenoidectomy
Interventions
Gabapentin, liquid placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
5 Years to 16 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Not listed Not applicable Interventional Accepts healthy volunteers

A Mobile Application for Child-focused Perioperative Education

NCT06054282
Conditions
Preoperative Anxiety
Interventions
"Ready for Tonsillectomy" educational mobile application
Behavioral
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
5 Years to 13 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Atlanta, Georgia
Active, not recruiting No phase listed Observational

Metabolomic Profiling of Racial Disparity

NCT06266429
Conditions
Adenoid Hypertrophy, Tonsillar Hypertrophy, Surgery
Interventions
Blood collection
Diagnostic Test
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
4 Years to 17 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Dexmedetomidine in Pediatric Tonsillectomy

NCT01057381
Conditions
Pediatric Adenotonsillectomy, Post Operative Analgesia
Interventions
Dexmedetomidine 0.75 mcg/kg, Morphine 50 mcg/kg, Morphine 100 mcg/kg, Dexmedetomidine 1 mcg/kg
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
3 Years to 17 Years
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Houston, Texas
Conditions
Sleep Apnea, Obstructive
Interventions
QuickClot
Device
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
2 Years to 17 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Norfolk, Virginia
Conditions
Tonsillectomy
Interventions
Virtual Reality, Midazolam
Device · Drug
Lead sponsor
Valley Anesthesiology Consultants
Other
Eligibility
5 Years to 11 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Phoenix, Arizona
Conditions
Tonsillectomy, Adenoidectomy
Interventions
Acetaminophen
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
3 Years to 17 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Sacramento, California
Conditions
Sleep Apnea, Obstructive
Interventions
Coblation (radiofrequency-based device)
Device
Lead sponsor
ArthroCare Corporation
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Pain
Interventions
Lidocaine, Saline
Drug
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
4 Years to 10 Years
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Pediatric Post-tonsillectomy Pain
Interventions
Dexamethasone, Placebo
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
4 Years to 17 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis
Interventions
Alternating Acetaminophen and Ibuprofen, Combined Acetaminophen and Ibuprofen
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
4 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Tonsillectomy
Interventions
Standard Care, ATC Dosing, Structured Pain Management Program, As needed dosing
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
6 Years to 15 Years
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2012
U.S. locations
1
States / cities
Madera, California
Completed Phase 2 Interventional Results available

Psychological Influences on Postoperative Recovery

NCT00581139
Conditions
Care, Postoperative, Pain, Postoperative, Surgical Procedures, Operative, Otorhinolaryngologic Surgical Procedures, Tonsillectomy, Adenoidectomy
Interventions
Preoperative Preparation Program (Child Life Specialist), Midazolam, Parental Presence during Induction of Anesthesia, PPIA preparation program PLUS Midazolam premedication
Behavioral · Drug · Other
Lead sponsor
University of California, Irvine
Other
Eligibility
3 Years to 12 Years
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Chronic Tonsillitis, Sleep Disordered Breathing
Interventions
Diet modification
Other
Lead sponsor
Georgetown University
Other
Eligibility
3 Years to 12 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Not applicable Interventional Results available

Acupuncture and Nausea/Vomiting in Pediatric Patients

NCT01417741
Conditions
Postoperative Vomiting and Nausea
Interventions
Acupuncture Needle
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
3 Years to 9 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Portland, Oregon
Completed Not applicable Interventional Results available

A Study of BiZact™ on Adults Undergoing Tonsillectomy

NCT02876575
Conditions
Tonsillectomy
Interventions
A bipolar instrument for tonsillectomies
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Houston, Texas
Conditions
Tonsillectomy, Adenoidectomy
Interventions
Ibuprofen, Acetaminophen
Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
2 Years to 18 Years
Enrollment
741 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
5
States / cities
San Diego, California • Boston, Massachusetts • San Antonio, Texas + 2 more
Completed Not applicable Interventional Results available

Use of Laryngeal Mask Airway in Pediatric Adenotonsillectomy

NCT01141660
Conditions
Laryngeal Mask Airway, Tonsillectomy
Interventions
Endotracheal Tube, Laryngeal mask airway
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
2 Years to 12 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Richmond, Virginia
Terminated Phase 4 Interventional Accepts healthy volunteers

Ketorolac Use in Pediatric Patients Undergoing Tonsillectomy

NCT03453541
Conditions
Analgesic Adverse Reaction
Interventions
Ketorolac Tromethamine, 0.9% Normal Saline
Drug
Lead sponsor
Albany Medical College
Other
Eligibility
2 Years to 18 Years
Enrollment
214 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Albany, New York
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Magnesium vs Placebo for Tonsillectomy

NCT02218424
Conditions
Pain
Interventions
Magnesium, Normal saline
Drug
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
4 Years to 10 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Secondary Post Tonsillectomy Hemorrhage, Primary Post Tonsillectomy Hemorrhage
Interventions
Ibuprofen
Drug
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
810 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
3
States / cities
Fort Sam Houston, Texas • Lackland Air Force Base, Texas • Tacoma, Washington
Completed Not applicable Interventional Results available

Adenotonsillectomy Postoperative Parental Teaching Tool

NCT02517658
Conditions
Tonsillectomy
Interventions
Video, Standard discharge teaching
Other
Lead sponsor
Sarah Khan
Other
Eligibility
Not listed
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Adenoidectomy, Tonsillectomy, Adenotonsillectomy
Interventions
Cuffed ETT, Uncuffed ETT
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Tonsillectomy, Tonsillitis Chronic, Hemorrhage, Postoperative Pain, Postoperative Hemorrhage, Surgery--Complications, Otorhinolaryngologic Diseases
Interventions
BiZact, Standard of care
Device · Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 18 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Houston, Texas