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Showing 1–24 of 36 matching trials from the live ClinicalTrials.gov search.
Conditions
Chronic Tonsillitis, Sleep Disordered Breathing
Interventions
Diet modification
Other
Lead sponsor
Georgetown University
Other
Eligibility
3 Years to 12 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Phase 4 Interventional Accepts healthy volunteers Results available

EXPAREL® for Pain After Tonsillectomy

NCT02444533
Conditions
Tonsillectomy, Tonsillitis, Post-operative Pain
Interventions
Liposomal Bupivacaine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Adenotonsillar Hypertrophy, Obstructive Sleep Apnea, Tonsillitis, Adenoiditis
Interventions
Normal Saline, Dexmedetomidine
Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
3 Years to 16 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Tonsillitis, Tonsillectomy
Interventions
Gabapentin
Drug
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
3 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Tonsillitis, Pharyngitis
Interventions
Telithromycin (HMR3647), Penicillin
Drug
Lead sponsor
Sanofi
Industry
Eligibility
6 Months to 13 Years
Enrollment
314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Bridgewater, New Jersey
Conditions
Pharyngitis, Tonsillitis
Interventions
Azithromycin
Drug
Lead sponsor
Pfizer
Industry
Eligibility
12 Years to 17 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
6
States / cities
Rancho Cordova, California • Chicago, Illinois • Murray, Utah + 1 more
Conditions
Tonsillitis, Obstructive Sleep Apnea of Child
Interventions
Dexamethasone, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
3 Years to 12 Years
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Battlefield Auricular Acupuncture During Adult Tonsillectomies and Effect of Post op Pain and Nausea

NCT02571075
Conditions
Tonsillitis
Interventions
Auricular acupuncture
Other
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Fort Bragg, North Carolina
Conditions
Tonsillitis, Pain
Interventions
Codeine with acetaminophen, Tramadol suspension
Drug
Lead sponsor
Children's Hospitals and Clinics of Minnesota
Other
Eligibility
4 Years to 15 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Opioid-Free Anesthetic for Tonsillectomy

NCT04528173
Conditions
Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder, Surgery
Interventions
Ketorolac, Dexmedetomidine, Morphine, Fentanyl
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Years to 18 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Memphis, Tennessee
Conditions
Tonsillitis
Interventions
amoxicillin, azithromycin SR
Drug
Lead sponsor
Pfizer
Industry
Eligibility
2 Years to 12 Years
Enrollment
693 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
33
States / cities
Hoover, Alabama • Pelham, Alabama • Fresno, California + 20 more
Conditions
Tonsillitis, Sleep Disordered Breathing, Hernia, Hydrocele, Hypospadias, Undescended Testicle, Circumcision
Interventions
Disposal Aid
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
1 Year to 17 Years
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis
Interventions
Alternating Acetaminophen and Ibuprofen, Combined Acetaminophen and Ibuprofen
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
4 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Tonsillitis, Pharyngitis
Interventions
Telithromycin, Penicillin
Drug
Lead sponsor
Sanofi
Industry
Eligibility
13 Years and older
Enrollment
233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Bridgewater, New Jersey
Conditions
Pharyngitis, Tonsillitis
Interventions
Amoxicillin Pulsatile Release Multiparticulate Tablet (drug)
Drug
Lead sponsor
Advancis Pharmaceutical Corporation
Industry
Eligibility
12 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Salt Lake City, Utah
Completed Not applicable Interventional

Acupuncture for Tonsillectomy Pain

NCT01389349
Conditions
Children, Postoperative Pain, Tonsillar Hypertrophy, Obstructive Sleep Apnea, Chronic Tonsillitis
Interventions
Acupuncture, Sham Control
Other
Lead sponsor
Children's ENT of San Diego, Inc.
Other
Eligibility
2 Years to 17 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
El Centro, California • San Diego, California
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Pediatric Pain Optimization After Tonsillectomy

NCT05244226
Conditions
Obstructive Sleep Apnea, Tonsillitis, Pain, Procedural
Interventions
Fentanyl/Hydromorphone, Methadone
Drug
Lead sponsor
Duke University
Other
Eligibility
3 Years to 17 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Tonsillitis
Interventions
Fentanyl, Dexmedetomidine
Drug
Lead sponsor
Children's National Research Institute
Other
Eligibility
2 Years to 12 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Obstructive Tonsillar Hypertrophy, Tonsillitis
Interventions
Plasmaknife, Monopolar
Device
Lead sponsor
Children's Hospital of Michigan
Other
Eligibility
4 Years to 16 Years
Enrollment
100 participants
Timeline
Started 2007
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Pharyngitis, Tonsillitis
Interventions
azithromycin (Zithromax), placebo, azithromycin SR
Drug
Lead sponsor
Pfizer
Industry
Eligibility
13 Years and older
Enrollment
598 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
16
States / cities
Clearwater, Florida • Boise, Idaho • Meridian, Idaho + 8 more
Completed Phase 4 Interventional Results available

Acetaminophen's Efficacy For Post-operative Pain

NCT01721486
Conditions
Tonsillitis, Airway Obstruction, Difficulty Swallowing
Interventions
IV acetaminophen, PO acetaminophen
Drug
Lead sponsor
Kaveh Aslani, MD
Other
Eligibility
5 Years to 13 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Royal Oak, Michigan
Conditions
Sore Throat, Pharyngitis, Tonsillitis
Interventions
APC-111 MP Tablet, 775 mg
Drug
Lead sponsor
Advancis Pharmaceutical Corporation
Industry
Eligibility
12 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
35
States / cities
Birmingham, Alabama • Tallassee, Alabama • Phoenix, Arizona + 32 more
Conditions
Sleep-Disordered Breathing, Sleep Apnea Syndromes in Children, Sleep Apnea, Obstructive, Tonsillitis, Tonsillar Hypertrophy, Tonsil Stone, Tonsil Disease
Interventions
Lateral pharyngoplasty, Tonsillectomy
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
3 Years to 17 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
4
States / cities
Murrieta, California • Riverside, California • San Bernardino, California
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery

NCT04230681
Conditions
Obstructive Sleep Apnea, Tonsillitis
Interventions
Hydromorphone, Fentanyl
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
2 Years to 15 Years
Enrollment
189 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri