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ClinicalTrials.gov public records Last synced Sep 9, 2026, 8:47 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Tooth Clear all
Active, not recruiting Phase 1Phase 2 Interventional

Treatment of Charcot-Marie-Tooth Disease, Axonal, Type 2S (CMT2S) in an Individual Patient

NCT07223632
View directory record Official record
Conditions
Charcot Marie Tooth Disease (CMT), Neuromuscular Diseases (NMD)
Interventions
VCA-894A
Drug
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

BEhavioral EConomics for Oral Health iNnovation Pilot Trial

NCT03862443
View directory record Official record
Conditions
Toothbrushing, Dental Plaque, Parent-Child Relations, Oral Hygiene, Dental Caries
Interventions
Fixed Incentive, Drawing Incentive
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
6 Months to 42 Months
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2019 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Zirconia-based Primary Anterior Crowns With Retention Grooves Versus Without Retention Grooves

NCT06354647
View directory record Official record
Conditions
Dental Caries, Tooth Decay
Interventions
Zirconia-based primary anterior crowns with retention grooves, Zirconia-based primary anterior crowns without retention grooves
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
2 Years to 6 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Sep 9, 2026, 8:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

DPBRN Prevalence of Questionable Occlusal Caries Lesions

NCT01201447
View directory record Official record
Conditions
Dental Caries
Interventions
Not listed
Lead sponsor
Dental Practice-Based Research Network
Network
Eligibility
6 Years and older
Enrollment
2,624 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
6
States / cities
Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2011 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Precision of Complete-arch Digital Implant Impressions With Intraoral Scanning Versus Photogrammetry

NCT05972148
View directory record Official record
Conditions
Edentulous Jaw
Interventions
Digital scanning, Photogrammetry
Other
Lead sponsor
William Negreiros
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Primer Aligner Study

NCT02550938
View directory record Official record
Conditions
Malocclusion
Interventions
Invisalign
Device
Lead sponsor
Align Technology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
253 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
13
States / cities
Anthem, Arizona • Napa, California • Oakland, California + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Sep 9, 2026, 8:47 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers

NCT07337109
View directory record Official record
Conditions
Dentin Hypersensitivity
Interventions
Not listed
Lead sponsor
HALEON
Industry
Eligibility
18 Years and older
Enrollment
375 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 9, 2026, 8:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Alveolar Ridge Preservation Following Tooth Extraction.

NCT05505084
View directory record Official record
Conditions
Tooth Fractures, Tooth Extraction Status Nos, Caries
Interventions
Tooth extraction and ridge preservation using different barrier mermbranes
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Results available

A Study to Determine the Effects of Adding an Experimental Device With Mouthrinse to Oral Care Regimen

NCT01419626
View directory record Official record
Conditions
Gingivitis
Interventions
Interdental cleaning device with water, Interdental cleaning device with essential-oil mouthrinse
Device
Lead sponsor
Johnson & Johnson Consumer and Personal Products Worldwide
Industry
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 9, 2026, 8:47 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Effect of Tooth Position During Orthodontic Treatment on the Apnea/ Hypopnea Index (AHI)

NCT03299023
View directory record Official record
Conditions
Obstructive Sleep Apnea, Orthodontic Tooth Movement, Apnea, Sleep Disordered Breathing
Interventions
Medibyte Portable Monitor
Other
Lead sponsor
Harvard School of Dental Medicine
Other
Eligibility
8 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Sep 9, 2026, 8:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Plasma Neurofilament Light and Its Relationship With Omega-3 Status and Soccer Heading in Women Soccer Players

NCT05457023
View directory record Official record
Conditions
Brain Trauma
Interventions
Plasma Neurofilament Light (NF-L), Omega-3 Index, HeadCount Questionnaire
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 25 Years · Female only
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Effect of a Novel Sweetener on the pH of Dental Plaque.

NCT00739778
View directory record Official record
Conditions
Dental Caries
Interventions
food - novel sweetener, food vehicle blank, food - sweetener, positive control, food - sweetener, negative control
Other
Lead sponsor
Cargill
Industry
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 17, 2008 · Synced Sep 9, 2026, 8:47 PM EDT
Terminated No phase listed Observational

Radiation Dosimetry in Teeth

NCT00178347
View directory record Official record
Conditions
Radiation Tolerance
Interventions
Exposure to irradiation
Radiation
Lead sponsor
University of Rochester
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated May 18, 2009 · Synced Sep 9, 2026, 8:47 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Precision Orthodontics: Virtual Treatment Planning for Orthodontic Braces

NCT04002999
View directory record Official record
Conditions
Malocclusion, Malocclusion, Angle's Class
Interventions
3D printed ceramic bracket and tray, Stock ceramic bracket + 3D printed tray, Stock bracket, no tray
Device
Lead sponsor
Harvard School of Dental Medicine
Other
Eligibility
11 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intentional Pulpotomy to Preserve Hopeless Molars

NCT04385693
View directory record Official record
Conditions
Pulpitis, Dental Pulp Diseases, Tooth Diseases
Interventions
Pulpotomy, Extraction and placement of space maintainer
Procedure
Lead sponsor
University of Florida
Other
Eligibility
5 Years to 10 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Sep 9, 2026, 8:47 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Immediate Implant Outcomes With and Without Bone Augmentation

NCT05157009
View directory record Official record
Conditions
Tooth Loss, Bone Loss, Alveolar, Dental Diseases, Dental Trauma
Interventions
implant placement
Procedure
Lead sponsor
Verdugo, Fernando, DDS
Individual
Eligibility
20 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Gabriel, California
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional

Resin Polymer (NuSmile BioFlx) Compared to Stainless Steel Crowns (3M ESPE) for Restoration of Primary Molar Teeth

NCT06354634
View directory record Official record
Conditions
Dental Caries, Tooth Decay
Interventions
Resin polymer (NuSmile Bioflx) crown, Stainless steel crown
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
3 Years to 7 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Phase 2 Study to Evaluate the Microbiology, Safety and Tolerability of C16G2 Varnish and Strip in Adolescent and Adult Subjects

NCT03196219
View directory record Official record
Conditions
Dental Caries
Interventions
C16G2, Placebo
Drug
Lead sponsor
Armata Pharmaceuticals, Inc.
Industry
Eligibility
12 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Kalispell, Montana
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Sep 9, 2026, 8:47 PM EDT
Not listed Not applicable Interventional

Esthetic Crown Lengthening With Closed Piezoelectric in Comparison to Open Flap Approach

NCT05478317
View directory record Official record
Conditions
Altered Passive Eruption of Teeth
Interventions
ECL- mPZ, ECL-OF
Procedure
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 31, 2022 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Study to Determine the Anti-plaque Efficacy of Commerical Toothpastes and an Oral Rinse

NCT01024738
View directory record Official record
Conditions
Dental Plaque
Interventions
Fluoride, Triclosan, fluoride, Chlorhexidine Gluconate
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Paramus, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 2, 2009 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Early Phase 1 Interventional

Intensive Preventative Dental Program Pilot Study

NCT07218068
View directory record Official record
Conditions
Dental Diseases
Interventions
Fluoride varnish, Regular Care, Medical Oncology Care Team
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Phase 2 Interventional Results available

Naproxen Sodium/Acetaminophen Proof of Concept Dosing Study

NCT03879408
View directory record Official record
Conditions
Pain
Interventions
440 mg naproxen sodium with 1000 mg acetaminophen, 220 mg naproxen sodium with 650 mg acetaminophen, 10 mg hydrocodone + 650 mg acetaminophen, 440 mg naproxen sodium, Placebo tablet
Drug
Lead sponsor
Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division
Industry
Eligibility
17 Years to 50 Years
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 4, 2022 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pediatric Study to Access Pharmacokinetics and Safety of Oraqix Gel

NCT01591616
View directory record Official record
Conditions
Periodontal Disease
Interventions
lidocaine and prilocaine
Drug
Lead sponsor
Dentsply International
Industry
Eligibility
6 Years to 17 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 6, 2020 · Synced Sep 9, 2026, 8:47 PM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Evaluation of Three Pulp Vitality Tests

NCT02636504
View directory record Official record
Conditions
Dental Pulp Diseases, Dental Pulp Vitality Testing
Interventions
Laser Doppler Flowmetry
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 9, 2026, 8:47 PM EDT