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ClinicalTrials.gov public records Last synced May 22, 2026, 3:42 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 133 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Tooth Extraction Clear all
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Dental Pain
Interventions
Diclofenac Test (lower dose), Diclofenac Test (upper dose), Celecoxib 400 mg, Placebo
Drug
Lead sponsor
Iroko Pharmaceuticals, LLC
Industry
Eligibility
18 Years to 50 Years
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2012 · Synced May 22, 2026, 3:42 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Impacted Third Molar Tooth, Temporomandibular Joint Dysfunction Syndrome
Interventions
Restful Jaw Device
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 24 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced May 22, 2026, 3:42 AM EDT
Completed Phase 3 Interventional
View directory record Official record
Conditions
Pain, Acute
Interventions
cannabidiol, placebo, acetaminophen 500mg and ibuprofen 200mg combo
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 1, 2022 · Synced May 22, 2026, 3:42 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Tooth Extraction
Interventions
Xenograft
Device
Lead sponsor
NYU College of Dentistry
Other
Eligibility
20 Years to 90 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 8, 2021 · Synced May 22, 2026, 3:42 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Healthy, Tooth Extraction
Interventions
Extraction of wisdom teeth
Procedure
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced May 22, 2026, 3:42 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Healthy, Tooth Extraction
Interventions
MRI
Procedure
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced May 22, 2026, 3:42 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Tooth Loss
Interventions
Alveolar Ridge Reconstruction
Drug
Lead sponsor
Gustavo Avila-Ortiz DDS, MS, PhD
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced May 22, 2026, 3:42 AM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Tooth Extraction Status Nos, Post Operative Pain, Patient Satisfaction, Narcotic Use, Mobile App
Interventions
Mobile app
Other
Lead sponsor
Boston University
Other
Eligibility
18 Years to 40 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced May 22, 2026, 3:42 AM EDT
Completed Phase 1 Interventional
View directory record Official record
Conditions
Impacted Third Molar Tooth, Pain, Acute
Interventions
Ibuprofen, Acetaminophen, Placebo, Oxycodone
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 64 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced May 22, 2026, 3:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Dental Devices, Home Care
Interventions
Battery operated toothbrush, Manual toothbrush
Device
Lead sponsor
Church & Dwight Company, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 4, 2024 · Synced May 22, 2026, 3:42 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Dental Pain
Interventions
ARRY-371797, p38 inhibitor; oral, Placebo; oral
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
2
States / cities
San Marcos, Texas • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 20, 2021 · Synced May 22, 2026, 3:42 AM EDT
Not yet recruiting Phase 2 Interventional
View directory record Official record
Conditions
Post Operative Pain, Impacted Third Molar Tooth, Muscle Pain
Interventions
Temporo-masseteric Nerve Block Injection, Oral Pain Medications only
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced May 22, 2026, 3:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Tooth Stain
Interventions
Colgate® Regular Cavity Protection, Experimental Mouth Rinse, Crest® 3D White Multi-Care Whitening Rinse, Glamorous White, Fresh Mint
Drug · Other
Lead sponsor
Johnson & Johnson Consumer and Personal Products Worldwide
Industry
Eligibility
18 Years to 65 Years
Enrollment
227 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated May 31, 2015 · Synced May 22, 2026, 3:42 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Impacted Wisdom Teeth
Interventions
Caldolor, Ofirmev
Drug
Lead sponsor
Tufts University School of Dental Medicine
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced May 22, 2026, 3:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Tooth Extraction
Interventions
Mineralized freeze-dried bone allograft alone, Combination of Mineralized and demineralized freeze-dried bone allograft alone
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2014 · Synced May 22, 2026, 3:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Tooth Loss
Interventions
Amnion Allograft, Allograft
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 9, 2024 · Synced May 22, 2026, 3:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Dental Plaque
Interventions
Experimental: U-shaped Power Toothbrush, Placebo Comparator: Soft Manual Toothbrush
Device
Lead sponsor
Lander Enterprises, LLC
Industry
Eligibility
5 Years to 8 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 7, 2024 · Synced May 22, 2026, 3:42 AM EDT
Suspended No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Obstructive Sleep Apnea, Malocclusion
Interventions
Not listed
Lead sponsor
Mohamed Bazina
Other
Eligibility
10 Years to 15 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced May 22, 2026, 3:42 AM EDT
Completed Phase 3 Interventional
View directory record Official record
Conditions
Tooth, Impacted, Tooth Diseases, Stomatognathic Diseases
Interventions
Ibuprofen 200Mg Oral Cap, Ibuprofen 200Mg Oral Tablet, Placebo Liquid Capsule, Placebo Tablets
Drug · Other
Lead sponsor
Reckitt Benckiser Healthcare (UK) Limited
Industry
Eligibility
16 Years to 55 Years
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced May 22, 2026, 3:42 AM EDT
Not yet recruiting Not applicable Interventional
View directory record Official record
Conditions
Dehiscence, Tooth Extraction, Alveolar Bone Loss
Interventions
Minimally Invasive tooth extraction, Alveolar ridge preservation with ABCC, Resorbable collagen membrane (InterCollagen® Guide)
Procedure · Device
Lead sponsor
Debora Dias
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced May 22, 2026, 3:42 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available
View directory record Official record
Conditions
Healthy, Maxillary First Premolar Tooth Extraction, Canine Retraction
Interventions
Tooth movement
Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
11 Years to 35 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced May 22, 2026, 3:42 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Dental Pain
Interventions
XPF-001, placebo
Drug
Lead sponsor
Xenon Pharmaceuticals Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 15, 2012 · Synced May 22, 2026, 3:42 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Pain
Interventions
Valdecoxib, COX Inhibitor
Drug
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
7 Years to 35 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced May 22, 2026, 3:42 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Dental Pain
Interventions
Pre-Op pregabalin, Pre-Op Placebo 1, Post-Op pregabalin, Post-Op Placebo 1, Post-Op Placebo 2, Post-Op acetaminophen
Drug
Lead sponsor
Nevakar, Inc.
Industry
Eligibility
17 Years to 55 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced May 22, 2026, 3:42 AM EDT