- Conditions
- Peripheral Arterial Disease, Peripheral Vascular Disease, Amputation, Lower Limb Amputation Knee, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury)
- Interventions
- Ischemic Conditioning Low - Sham Comparator, Ischemic Conditioning High - Active Comparator
- Procedure
- Lead sponsor
- University of Illinois at Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
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Showing 1–24
of 63
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury), Phantom Limb Pain
- Interventions
- Distractor and Lower limb VR
- Device
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Lower Limb Amputation
- Interventions
- Conventional Prosthetic Transfemoral Socket System, Novel Prosthetic transfemoral socket system
- Device
- Lead sponsor
- Ohio Willow Wood
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 8 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2014
- U.S. locations
- 2
- States / cities
- Columbus, Ohio • Mount Sterling, Ohio
- Conditions
- Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation Above Knee (Injury)
- Interventions
- Questionnaire
- Other
- Lead sponsor
- Minneapolis Veterans Affairs Medical Center
- Federal
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Transfemoral Amputation
- Interventions
- MIT Powered Knee
- Device
- Lead sponsor
- Massachusetts Institute of Technology
- Other
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2026
- U.S. locations
- 1
- States / cities
- Cambridge, Massachusetts
- Conditions
- Unilateral Transfemoral Amputation
- Interventions
- Level overground ambulation
- Other
- Lead sponsor
- Southern California Institute for Research and Education
- Other
- Eligibility
- 18 Years to 65 Years · Male only
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Long Beach, California
- Conditions
- Lower Limb Amputation
- Interventions
- Active vacuum test prosthesis
- Device
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Transfemoral Amputation, Unilateral Traumatic Amputation of Leg at or Above Knee
- Interventions
- C leg compared to subject's mechanical leg (Otto Bock)
- Device
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2019
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Prosthesis and Implants
- Interventions
- Transdermal Compress Device
- Device
- Lead sponsor
- Balmoral Medical company
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2031
- U.S. locations
- 9
- States / cities
- Sacramento, California • Aurora, Colorado • Chicago, Illinois + 6 more
- Conditions
- Transfemoral Amputation
- Interventions
- Powered Microprocessor-controlled Knee (PMPK)
- Other
- Lead sponsor
- Loma Linda University
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Loma Linda, California
- Conditions
- Lower Limb Amputation Above Knee (Injury), Congenital Amputation of Lower Limb, Lower Limb Amputation Knee
- Interventions
- Kenevo or C-Leg 4, Non microprocessor controlled knee (NMPK)
- Device
- Lead sponsor
- Otto Bock Healthcare Products GmbH
- Industry
- Eligibility
- 65 Years and older
- Enrollment
- 107 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 90
- States / cities
- Dothan, Alabama • Gilbert, Arizona • Phoenix, Arizona + 85 more
- Conditions
- Amputation
- Interventions
- Ischial Ramus Containment (IRC), Dynamic Socket Ischial Ramus Containment (IRC), Sub-Ischial Interface (Sub-I)
- Device
- Lead sponsor
- University of South Florida
- Other
- Eligibility
- 18 Years to 44 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Tampa, Florida
- Conditions
- Amputation, Artificial Limbs
- Interventions
- Northwestern University Flexible Sub-Ischial Vacuum Socket, Ischial Containment Socket
- Device
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 3
- States / cities
- Chicago, Illinois • Oakbrook Terrace, Illinois
- Conditions
- Amputation
- Interventions
- iFIT Transtibial Prosthesis, iFIT Transfemoral Prosthesis
- Device
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 71 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Amputation, Prostheses and Implants
- Interventions
- Intramuscular electrodes
- Device
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Knee
- Interventions
- Revo-M, Taleo, Proflex XC
- Device
- Lead sponsor
- Otto Bock Healthcare Products GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 4
- States / cities
- Mesa, Arizona • Linthicum, Maryland • Dayton, Ohio + 1 more
- Conditions
- Lower-Limb Amputation
- Interventions
- Exercise self-management, Attention control
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 40 Years to 89 Years
- Enrollment
- 95 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Lower Limb Amputation Above Knee (Injury)
- Interventions
- Microprocessor Knee (MPK), Non-Microprocessor Knee (NMPK)
- Device
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Transfemoral Amputation
- Interventions
- Active knee (Ossur Power Knee II), Adaptive knee (Ossur Rheo), Passive knee (Various manufacturers)
- Device
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 45 Years to 75 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Amputation
- Interventions
- Vacuum assisted socket technology (Harmony System, Otto Bock Healthcare)
- Device
- Lead sponsor
- Stony Brook University
- Other
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 2
- States / cities
- Stony Brook, New York • West Babylon, New York
- Conditions
- Wound Healing, Lower Extremity Amputation, Above Knee Amputation, Below Knee Amputation
- Interventions
- Lower Extremity Amputation, SPY Elite Imaging System, Indocyaine Green
- Procedure · Device · Drug
- Lead sponsor
- Corewell Health West
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Grand Rapids, Michigan
- Conditions
- Amputation of Lower Limb Above Knee, Amputee, Amputation
- Interventions
- Bio Leg
- Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 40 Years to 70 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida
- Conditions
- Amputation
- Interventions
- Powered knee and ankle prosthesis
- Device
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Transfemoral Amputation
- Interventions
- Northwestern University Flexible Subischial Suction Socket (NU-FlexSIS)
- Device
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 84 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 3
- States / cities
- Minneapolis, Minnesota • Houston, Texas • Seattle, Washington