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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Transgender Persons Clear all
Terminated Early Phase 1 Interventional Accepts healthy volunteers

Coagulation and Fibrinolysis of Estradiol in Transwomen

NCT05387577
View directory record Official record
Conditions
Transgenderism, Clotting Disorder
Interventions
Estradiol Tablets, Transdermal patch
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Male only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 20, 2022 · Synced Jul 22, 2026, 11:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Providing Online Counseling for Home-Based HIV Testing With Transgender Youth

NCT03185975
View directory record Official record
Conditions
Hiv, Transgender Youth
Interventions
at-home test kit, Motivational Interviewing and Certified Testing and Referral
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
15 Years to 24 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 20, 2019 · Synced Jul 22, 2026, 11:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PrEPTECH Phase 2 Study of a PrEP Telehealth Intervention

NCT04902820
View directory record Official record
Conditions
Pre-Exposure Prophylaxis, HIV, Telemedicine
Interventions
PrEPTECH website, Online PrEP resource list
Other
Lead sponsor
ETR Associates
Other
Eligibility
15 Years to 27 Years · Male only
Enrollment
229 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Scotts Valley, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2023 · Synced Jul 22, 2026, 11:58 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Pre-Exposure Prophylaxis for Transgender Women in the US and South America

NCT04742491
View directory record Official record
Conditions
HIV Prevention
Interventions
Immediate Intervention Arm, Deferred Intervention Arm
Drug
Lead sponsor
HIV Prevention Trials Network
Network
Eligibility
18 Years and older · Male only
Enrollment
304 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
4
States / cities
San Francisco, California • New York, New York • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Jul 22, 2026, 11:58 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Microeconomic Intervention to Reduce HIV Transmission in Economically Disadvantaged Transgender Women

NCT04275310
View directory record Official record
Conditions
Hiv, Transgenderism
Interventions
Microeconomic Intervention
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 3, 2023 · Synced Jul 22, 2026, 11:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Health Outcomes in Young Cisgender Men and Transgender Women (mLab App)

NCT03803683
View directory record Official record
Conditions
HIV Infections
Interventions
mLab App, HIV Prevention Information, HIV Home Tests
Device · Behavioral
Lead sponsor
Rebecca Schnall, RN, MPH, PhD
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
525 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Chicago, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 25, 2024 · Synced Jul 22, 2026, 11:58 AM EDT
Active, not recruiting Not applicable Interventional

Forward to Quit: A Person-centered Mobile Technology Intervention for Smoking Cessation Among Transgender Adults

NCT07181551
View directory record Official record
Conditions
Smoking Cessation
Interventions
Forward to Quit (F2Q)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Jul 22, 2026, 11:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

BC Risk Assessment Before Top Surgery

NCT06239766
View directory record Official record
Conditions
Breast Cancer, Risk Reduction
Interventions
Breast Cancer Risk Assessment
Diagnostic Test
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Jul 22, 2026, 11:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Feminizing Hormone Therapy and the Rectal Mucosa Immune Environment in Transgender Women

NCT04531943
View directory record Official record
Conditions
HIV Prevention
Interventions
Estrogen, Estrogen plus Progesterone
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 59 Years
Enrollment
285 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 16, 2025 · Synced Jul 22, 2026, 11:58 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Evaluating Drug Interactions Between Doravirine With Estradiol and Spironolactone in Healthy Transgender Women

NCT04283656
View directory record Official record
Conditions
Transgender Health, Gender Dysphoria, Transgender Women, Human Immunodeficiency Virus
Interventions
Doravirine/Lamivudine/Tenofovir, Spironolactone 100mg, Estradiol 2mg, Placebo
Drug · Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Jul 22, 2026, 11:58 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Long-acting Biomedical HIV Prevention in Transgender Women

NCT03856580
View directory record Official record
Conditions
HIV Prevention, Transgender Women
Interventions
Alternative long-acting PrEP injection strategies, mHealth adherence app
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 100 Years · Male only
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Jul 22, 2026, 11:58 AM EDT
Terminated Not applicable Interventional

Progressive Tension Sutures in Gender Affirming Mastectomy

NCT04818580
View directory record Official record
Conditions
Hematoma, Seroma
Interventions
Progressive Tension Sutures
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older · Male only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 29, 2023 · Synced Jul 22, 2026, 11:58 AM EDT
Completed Phase 4 Interventional Results available

A Demonstration Project to Add Pre- or Post-exposure Prophylaxis to Combination HIV Prevention Services

NCT01781806
View directory record Official record
Conditions
HIV Prevention
Interventions
emtricitabine 200mg/tenofovir 300mg
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Male only
Enrollment
328 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Jul 22, 2026, 11:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Linkage of Transgender Individuals to PrEP

NCT03191474
View directory record Official record
Conditions
HIV Seronegativity, Linkage
Interventions
T-POWr Intervention
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Los Angeles, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 12, 2021 · Synced Jul 22, 2026, 11:58 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility and Acceptability of Mindful Self-Compassion Among Transgender and Nonbinary Young Adults

NCT06409975
View directory record Official record
Conditions
Healthy
Interventions
Mindful Self-Compassion (MSC)
Behavioral
Lead sponsor
University of Rhode Island
Other
Eligibility
18 Years to 29 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 22, 2026, 11:58 AM EDT
Completed Not applicable Interventional Results available

AllyQuest Adherence App Intervention for HIV-positive Men Who Have Sex With Men and Transgender Women: Pilot Trial

NCT03916484
View directory record Official record
Conditions
Hiv, HIV/AIDS, Medication Adherence, Sexual Behavior, Sexually Transmitted Infections (Not HIV or Hepatitis)
Interventions
AllyQuest HIV Medication Adherence app-delivered intervention, AllyQuest HIV Medication Adherence app-delivered intervention + NSC
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
15 Years to 29 Years · Male only
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
6
States / cities
Birmingham, Alabama • Detroit, Michigan • Newark, New Jersey + 3 more
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Jul 22, 2026, 11:58 AM EDT
Completed No phase listed Observational

Effect of Hormone Therapy on Renal Function

NCT04482920
View directory record Official record
Conditions
Transgenderism, Kidney Diseases, Kidney Injury
Interventions
p-aminohippurate clearance study, Iohexol infusion
Diagnostic Test
Lead sponsor
University of Colorado, Denver
Other
Eligibility
17 Years to 30 Years
Enrollment
22 participants
Timeline
2021 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Jul 22, 2026, 11:58 AM EDT
Recruiting Not applicable Interventional

WePrEP: Developing a PrEP Shared Decision-making Tool for Transgender Women

NCT06656676
View directory record Official record
Conditions
HIV Prevention
Interventions
WePrEP: A shared decision-making tool, Active comparator: CDC recommendations for discussing PrEP
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Sheridan, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Jul 22, 2026, 11:58 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Stick2PrEP Cisgender Women and Trans Individuals

NCT05165745
View directory record Official record
Conditions
HIV Prevention, Pre-exposure Prophylaxis
Interventions
Individualized Feedback
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Jul 22, 2026, 11:58 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Digital Limited Interaction Efficacy Trial of LifeSkills Mobile to Reduce HIV Incidence in YTW

NCT05018611
View directory record Official record
Conditions
HIV Prevention
Interventions
LifeSkills Mobile
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
16 Years to 29 Years · Male only
Enrollment
5,100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jul 22, 2026, 11:58 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

HIV Prevention Among At-risk Latinos in the Heartland

NCT04563715
View directory record Official record
Conditions
HIV Infections
Interventions
HIV counseling and testing, Network intervention
Diagnostic Test · Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Male only
Enrollment
456 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
3
States / cities
Indianapolis, Indiana • Cleveland, Ohio • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Jul 22, 2026, 11:58 AM EDT
Completed Not applicable Interventional

Evaluating the Efficacy of the Parent Support Program

NCT04531761
View directory record Official record
Conditions
Prejudice, Gender Identity, Knowledge, Attitudes, Practice
Interventions
Parent Support Program
Behavioral
Lead sponsor
Palo Alto University
Other
Eligibility
18 Years and older
Enrollment
570 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Jul 22, 2026, 11:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Trans Women Connected Mobile App for Changes in Sexual Health-related Behavior Among Transgender Women

NCT03897049
View directory record Official record
Conditions
HIV/AIDS, Health Knowledge, Attitudes, Practice, STI
Interventions
Trans Women Connected, General Health App
Behavioral
Lead sponsor
ETR Associates
Other
Eligibility
18 Years to 49 Years
Enrollment
574 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Scotts Valley, California
Source: ClinicalTrials.gov public record
Updated May 5, 2024 · Synced Jul 22, 2026, 11:58 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Finding the Right Tenofovir/Emtricitabine Regimen for Pre-Exposure Prophylaxis (PrEP) in Transgender Women

NCT03060785
View directory record Official record
Conditions
HIV Prevention
Interventions
Tenofovir Disoproxil Fumarate/Emtricitabine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Jul 22, 2026, 11:58 AM EDT