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ClinicalTrials.gov public records Last synced Oct 25, 2026, 4:51 AM EDT

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Showing 1–24 of 3,572 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Trauma, Nervous System Clear all
Completed Phase 2Phase 3 Interventional

Health Interventions for Survivors and Primary Support Persons of Spinal Cord Injury

NCT00148239
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Caregiver Only Intervention, Dual Treatment, Control
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
30 Years and older
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
2
States / cities
Miami, Florida • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Oct 25, 2026, 4:51 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Vestibular Consequences of Blast-related Mild Traumatic Brain Injury (TBI)

NCT01021137
View directory record Official record
Conditions
Dizziness, Brain Injury
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Mountain Home, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Oct 25, 2026, 4:51 AM EDT
Active, not recruiting Not applicable Interventional

Home Based Tele-exercise for People With Chronic Neurological Impairments

NCT04564495
View directory record Official record
Conditions
Neurologic Disorder, Stroke, Spinal Cord Injuries, Cerebral Palsy, Hemiplegia, Hemiparesis, Multiple Sclerosis, Parkinson Disease, Trauma, Brain, Transverse Myelitis, Friedreich Ataxia
Interventions
Seated exercise
Behavioral
Lead sponsor
Burke Medical Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 25, 2026, 4:51 AM EDT
Completed Not applicable Interventional Results available

Cognitive-Behavioral Therapy for Veterans With TBI

NCT02658669
View directory record Official record
Conditions
Insomnia, Traumatic Brain Injury
Interventions
Cognitive-Behavioral Therapy for Insomnia, Sleep Education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 55 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Oct 25, 2026, 4:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Mindfulness Based Stress Reduction on Patients With Traumatic Brain Injury

NCT01613872
View directory record Official record
Conditions
Traumatic Brain Injury, Brain Injury, Stress
Interventions
Mindfulness Based Stress Reduction
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
30 Years to 50 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 1, 2014 · Synced Oct 25, 2026, 4:51 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Safety and Feasibility of Minocycline in the Treatment of Traumatic Brain Injury (TBI)

NCT01058395
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Minocycline
Drug
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 75 Years · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Dearborn, Michigan • Trenton, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Oct 25, 2026, 4:51 AM EDT
Recruiting Not applicable Interventional

MindEx: A Novel, Multifocal, Cognitive Brain-Machine Interface System

NCT05936619
View directory record Official record
Conditions
Paralysis; Quadriplegic, Quadraplegia, Tetraplegia, Tetraplegic Motor Dysfunction Following Brainstem or Spinal Cord Injury, Cervical Spinal Cord Injury, Amyotrophic Lateral Sclerosis (ALS), Brainstem Stroke, Paralysis, Brain-computer Interface
Interventions
Mind Extender (MindEx)
Device
Lead sponsor
Nader Pouratian
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 25, 2026, 4:51 AM EDT
Completed No phase listed Observational

EVALUATION OF BIOMARKERS OF TRAUMATIC BRAIN INJURY EXTENSION STUDY

NCT02439736
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Blood draw within 12 hours of head injury
Other
Lead sponsor
Banyan Biomarkers, Inc
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
5
States / cities
San Diego, California • Detroit, Michigan • Houston, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2017 · Synced Oct 25, 2026, 4:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hyporeactivity and Gulf War Illness

NCT00100412
View directory record Official record
Conditions
Gulf War Syndrome, Chronic Fatigue Syndrome, Post-Traumatic Stress Disorder
Interventions
Graded dobutamine infusions, Graded phenylephrine injections, Psychosocial challenge involving socioevaluative public speaking
Drug · Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
1
States / cities
East Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 25, 2026, 4:51 AM EDT
Recruiting No phase listed Observational

The International Spinal Cord Injury Blood Biomarker Longitudinal Evaluation (I-SCRIBBLE) Study

NCT06839300
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Not listed
Lead sponsor
AO Foundation, AO Spine
Other
Eligibility
19 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 25, 2026, 4:51 AM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy

NCT05586581
View directory record Official record
Conditions
HIV Associated Neurocognitive Disorder, HIV Dementia, HIV Encephalitis, Healthy
Interventions
SV2A PET, TSPO PET
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 25, 2026, 4:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder

NCT05780177
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Insomnia Disorder
Interventions
Brief Behavioral Treatment for Insomnia (BBTI), Progressive Muscle Relaxation Training (PMRT)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 25, 2026, 4:51 AM EDT
Not yet recruiting Not applicable Interventional

Therapeutic Benefits of Pareidolia in Acute Traumatic Brain Injury Patients

NCT07867119
View directory record Official record
Conditions
Traumatic Brain Injuries
Interventions
Therapeutic Benefits of Pareidolia, Active Comparator #1
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 25, 2026, 4:51 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Transforming Research and Clinical Knowledge in Traumatic Brain Injury Epileptogenesis Project (TRACK-TBI EPI)

NCT05823766
View directory record Official record
Conditions
Traumatic Brain Injury, Post-traumatic Epilepsy
Interventions
In-Person Outcome Assessment, 3T Magnetic Resonance Imaging (MRI), Clinical Visit, Blood Draw, EEG, Telephone Outcome Assessment
Behavioral · Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
9
States / cities
San Francisco, California • Charlestown, Massachusetts • Cincinnati, Ohio + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 25, 2026, 4:51 AM EDT
Completed Phase 4 Interventional Results available

Zoledronic Acid Administration in Acute Spinal Cord Injury

NCT02042872
View directory record Official record
Conditions
Disuse Osteoporosis
Interventions
Zoledronic acid
Drug
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 49 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 14, 2018 · Synced Oct 25, 2026, 4:51 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Deployment Health in Regular Military Women

NCT01692067
View directory record Official record
Conditions
Military Physical and Sexual Trauma, Combat Trauma, PTSD, TBI
Interventions
Not listed
Lead sponsor
Iowa City Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 60 Years
Enrollment
871 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
2
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 19, 2019 · Synced Oct 25, 2026, 4:51 AM EDT
Completed No phase listed Observational

Determine the Association Between the Level of SCI With Chronic Respiratory Symptoms, Measures of Pulmonary Function, and Respiratory Illness.

NCT00011336
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2002
U.S. locations
1
States / cities
West Roxbury, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 25, 2026, 4:51 AM EDT
Completed Not applicable Interventional

Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial

NCT04274530
View directory record Official record
Conditions
Pain, Postoperative, Pain, Acute, Pain, Chronic, Fractures, Closed, Fractures, Open
Interventions
Cognitive Behavioural Therapy
Behavioral
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Enrollment
1,024 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
6
States / cities
Indianapolis, Indiana • Baltimore, Maryland • Largo, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2025 · Synced Oct 25, 2026, 4:51 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Post-Concussion Musculoskeletal Injury Risks

NCT05122728
View directory record Official record
Conditions
Musculoskeletal Injury
Interventions
Post-Concussion Neuromuscular Function and Musculoskeletal Injury Risk Assessment
Other
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 40 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
3
States / cities
Athens, Georgia • Bethesda, Maryland • Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 25, 2026, 4:51 AM EDT
Completed Not applicable Interventional Results available

Vasopressin Versus Catecholamines for Cerebral Perfusion Pressure Control in Brain Injured Trauma Patients

NCT00795366
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
arginine vasopressin, Standard catecholamine
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 12, 2014 · Synced Oct 25, 2026, 4:51 AM EDT
Terminated Early Phase 1 Interventional

Liposomal Bupivicaine for Skin Graft Donor Sites in Burn Patients

NCT03705637
View directory record Official record
Conditions
Burns, Postoperative Pain
Interventions
Exparel
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 2, 2023 · Synced Oct 25, 2026, 4:51 AM EDT
Not listed No phase listed Observational

Fatigue, Sleep Disorders and Endocrine Abnormalities in TBI Patients

NCT00775775
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 6, 2009 · Synced Oct 25, 2026, 4:51 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Clinical Evaluation of a Novel Balance, Vestibular and Oculomotor Assessment Tool

NCT02171312
View directory record Official record
Conditions
Mild Concussion, Post Concussion Syndrome, Vestibular Neuritis
Interventions
iDETECT Assessment, Routine Balance and Vestibular Testing
Device · Behavioral
Lead sponsor
Emory University
Other
Eligibility
12 Years and older
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 9, 2016 · Synced Oct 25, 2026, 4:51 AM EDT
Withdrawn No phase listed Observational

Middle Meningeal Artery Embolization for Chronic Subdural Hematoma

NCT04065113
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Middle Meningeal Artery Embolization with polyvinyl alcohol particles (PVA), Drainage of Subdural Hematoma
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Oct 25, 2026, 4:51 AM EDT