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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Traumatic Amputation Clear all
Recruiting No phase listed Observational

A Real-World Registry of Chronic Wounds and Ulcers

NCT02280733
View directory record Official record
Conditions
Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis, Skin Ulcer, Leg Ulcer, Pyoderma, Peripheral Arterial Disease, Lymphedema, Surgical Complication, Venous Leg Ulcers (VLUs), Calciphylaxis, Sickle Cell Ulcer, Pressure Ulcer (PU), Diabetic Foot Ulcers (DFUs), Pressure Injury, Arterial Ulcers, Soft Tissue Radionecrosis (STRN), Traumatic Wounds, Chronic Ulcer
Interventions
Usual care
Other
Lead sponsor
U.S. Wound Registry
Other
Eligibility
Not listed
Enrollment
300,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2030
U.S. locations
1
States / cities
The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Jul 22, 2026, 5:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Prosthetic Components and Stability in Amputee Gait

NCT00167778
View directory record Official record
Conditions
Diabetes Mellitus, Leg Injuries, Traumatic Amputation
Interventions
Transverse plane rotation adaptor pylon, Rigid pylon
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 14, 2014 · Synced Jul 22, 2026, 5:06 PM EDT
Completed Not applicable Interventional

SoftHand Comparison Study

NCT05328934
View directory record Official record
Conditions
Upper Extremity Injury, Upper Extremity Deformities, Congenital, Amputation, Traumatic, Amputation, Congenital
Interventions
SoftHand Pro, Ossur i-Limb
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 99 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Tempe, Arizona • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Jul 22, 2026, 5:06 PM EDT
Active, not recruiting Not applicable Interventional Results available

Optimizing Rehabilitation for Phantom Limb Pain Using Mirror Therapy and Transcranial Direct Current Stimulation (tDCS)

NCT02487966
View directory record Official record
Conditions
Phantom Limb Pain, Amputation, Traumatic
Interventions
transcranial Direct Current Stimulation (tDCS): active (Soterix ©), Mirror Therapy: active, transcranial Direct Current Stimulation (tDCS): sham (Soterix ©), Mirror Therapy: Sham
Device · Behavioral
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Jul 22, 2026, 5:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Wearing a Powered Ankle-Foot Prosthesis on Amputee Walking

NCT00869947
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Powered ankle-foot prosthesis, No device
Device · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 24, 2014 · Synced Jul 22, 2026, 5:06 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development of a Simulation Tool for Upper Extremity Prostheses

NCT01622530
View directory record Official record
Conditions
Traumatic Amputation of Upper Limb, Level Unspecified
Interventions
Not listed
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Jul 22, 2026, 5:06 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Criteria for Advanced Prosthetic Foot Prescription

NCT03505983
View directory record Official record
Conditions
Prosthesis User, Amputation; Traumatic, Limb, Lower
Interventions
ESR Prosthetic Foot First, Articulating ESR Prosthetic Foot First, Powered Prosthetic Foot First
Device
Lead sponsor
VA New York Harbor Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Jul 22, 2026, 5:06 PM EDT
Completed Not applicable Interventional Results available

No Power Bionic Lower Extremity Prosthesis

NCT04070105
View directory record Official record
Conditions
Amputation, Amputation, Traumatic, Amputation; Traumatic, Leg, Lower
Interventions
Compliant Adaptive Energy Storage and Return Foot, AllPro
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 26, 2024 · Synced Jul 22, 2026, 5:06 PM EDT
Completed Not applicable Interventional

Comparison of Pattern Recognition Control and Direct Control in TMR

NCT03097978
View directory record Official record
Conditions
Amputation, Amputation; Traumatic, Arm, Upper
Interventions
Commercial system, RIC arm system, Direct Control, Pattern Recognition
Device · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 95 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Jul 22, 2026, 5:06 PM EDT
Withdrawn No phase listed Observational

Hand Transplantation: Functional and Quality of Life Outcomes

NCT02331355
View directory record Official record
Conditions
Amputation; Traumatic, Arm, Upper, Between Shoulder and Elbow, Amputation; Traumatic, Hand, Amputation; Traumatic, Hand, Both, Amputation; Traumatic, Arm: Forearm, at Elbow Level, Amputation; Traumatic, Arm, Upper
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 15, 2020 · Synced Jul 22, 2026, 5:06 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Human Upper Extremity (Hand and Forearm) Allotransplantation

NCT00722280
View directory record Official record
Conditions
Amputation, Traumatic
Interventions
Hand Transplantation
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 60 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Jul 22, 2026, 5:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Outcomes With Passive MPKs vs. Powered Prosthetic Knees

NCT05267639
View directory record Official record
Conditions
Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User, Lower Limb Amputation Above Knee (Injury), Amputation; Traumatic, Leg: Thigh, Between Hip and Knee
Interventions
Power Knee
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Holliston, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Jul 22, 2026, 5:06 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Reiki for the Management of Neuropathic Pain

NCT02328703
View directory record Official record
Conditions
Neuropathic Pain, Amputation, Traumatic
Interventions
Reiki Therapy
Other
Lead sponsor
Fort Belvoir Community Hospital
Federal
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Jul 22, 2026, 5:06 PM EDT
Terminated Not applicable Interventional Results available

Spinal Cord Stimulation for Restoration of Function in Lower-Limb Amputees, 90-Day

NCT04547582
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity, Phantom Limb Pain
Interventions
Spinal cord stimulator
Device
Lead sponsor
Lee Fisher, PhD
Other
Eligibility
22 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Jul 22, 2026, 5:06 PM EDT
Recruiting Not applicable Interventional

Effects of Microprocessor-controlled Prosthetic Knees on Fall-related Health Outcomes in Limited Community Ambulators

NCT06937242
View directory record Official record
Conditions
Amputation, Prosthesis User, Amputation; Traumatic, Leg: Thigh, Between Hip and Knee, Limb; Absence, Congenital, Lower, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Above Knee
Interventions
Ottobock C-Leg 4 Microprocessor Knee, Ottobock Kenevo
Device
Lead sponsor
Hanger Institute for Clinical Research and Education, LLC
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Jul 22, 2026, 5:06 PM EDT
Completed Not applicable Interventional

Pattern Recognition Prosthetic Control

NCT04272593
View directory record Official record
Conditions
Prosthesis User, Congenital Amputation of Upper Limb, Amputation; Traumatic, Limb
Interventions
EMG-Pattern Recognition Controller
Device
Lead sponsor
Coapt, LLC
Industry
Eligibility
18 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 19, 2022 · Synced Jul 22, 2026, 5:06 PM EDT
Recruiting Not applicable Interventional

To Assess the Utility of the Point Mini in a Clinical Take-home Study

NCT06501092
View directory record Official record
Conditions
Amputation; Traumatic, Hand, Amputation, Congenital
Interventions
Point Mini
Device
Lead sponsor
Point Designs
Industry
Eligibility
3 Years to 17 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Lafayette, Colorado • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 22, 2026, 5:06 PM EDT
Withdrawn No phase listed Observational

A Comparison of the Outcomes of Distal Fingertip Amputations Treated With Either Artificial (Xeroform) or Biological Dressings

NCT03968835
View directory record Official record
Conditions
Finger Injuries, Amputation, Traumatic
Interventions
Bacitracin, Skin Graft
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
Up to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2020 · Synced Jul 22, 2026, 5:06 PM EDT
Completed Not applicable Interventional

Spinal Root and Spinal Cord Stimulation for Restoration of Function in Lower-Limb Amputees

NCT03027947
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity, Phantom Limb Pain
Interventions
Spinal cord stimulator
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Jul 22, 2026, 5:06 PM EDT
Not listed Phase 1 Interventional

Acupuncture for the Treatment of Phantom Limb and Residual Limb Pain After Amputation

NCT00388752
View directory record Official record
Conditions
Phantom Limb, Residual Limb Pain, Traumatic Amputation, Amputation
Interventions
Acupuncture
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 5, 2007 · Synced Jul 22, 2026, 5:06 PM EDT
Recruiting No phase listed Observational

Human Upper Extremity Allotransplantation: F/U Protocol

NCT03400345
View directory record Official record
Conditions
Amputation, Traumatic, Wounds and Injury, Hand Injuries
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2036
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jul 22, 2026, 5:06 PM EDT
Completed Not applicable Interventional

Assessing Force Feedback With the SoftHand Pro

NCT03412656
View directory record Official record
Conditions
Amputation, Traumatic, Limb Defect
Interventions
SoftHand Pro with CUFF force feedback device
Device
Lead sponsor
Kristin Zhao, PhD
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Jul 22, 2026, 5:06 PM EDT
Active, not recruiting No phase listed Observational

Kinematics of Ewing Amputees

NCT06371209
View directory record Official record
Conditions
Lower Extremity Amputation, Trans-Tibial Amputation, Traumatic Lower Extremity Amputation, Agonist-Antagonist Myoneural Interface
Interventions
Modified Amputation, Standard Amputation
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 22, 2026, 5:06 PM EDT
Not listed Not applicable Interventional

Application of Targeted Reinnervation for People With Transradial Amputation

NCT02349035
View directory record Official record
Conditions
Amputation; Traumatic, Hand, and Wrist, Amputation; Traumatic, Hand, at Wrist Level
Interventions
Compare control of multifunction transradial prosthesis, Perform TMR surgery and evaluate transradial TMR pattern recognition control of multifunctional prostheses.
Device · Procedure
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 95 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
3
States / cities
Chicago, Illinois • Bethesda, Maryland • Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced Jul 22, 2026, 5:06 PM EDT