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ClinicalTrials.gov public records Last synced Oct 2, 2026, 5:18 AM EDT

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Showing 25–48 of 79 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Traumatic Intracranial Hemorrhage Clear all
Completed Not applicable Interventional

Cerebral Perfusion Pressure (CPP) Management Information Feedback and Nursing

NCT00194441
View directory record Official record
Conditions
Traumatic Brain Injury, Subarachnoid Hemorrhage
Interventions
Bedside display of cerebral perfusion pressure information
Other
Lead sponsor
University of Washington
Other
Eligibility
Not listed
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2008
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 2, 2014 · Synced Oct 2, 2026, 5:18 AM EDT
Completed Not applicable Interventional

Comparative Effectiveness of Family Problem-Solving Therapy (F-PST) for Adolescent TBI

NCT02368366
View directory record Official record
Conditions
Tbi, Intracranial Edema, Brain Edema, Craniocerebral Trauma, Head Injury, Brain Hemorrhage, Traumatic, Subdural Hematoma, Brain Concussion, Head Injuries, Closed, Epidural Hematoma, Cortical Contusion, Wounds and Injuries, Disorders of Environmental Origin, Trauma, Nervous System, Brain Injuries
Interventions
Therapist Guided Face to Face Family Problem Solving, Therapist Guided Online Family Problem Solving, Self-Guided Online Family Problem Solving
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
14 Years to 19 Years
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
5
States / cities
Denver, Colorado • Cincinnati, Ohio • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Oct 2, 2026, 5:18 AM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Efficacy and Feasibility Trial of a Portable Near Infra-Red Hematoma Imager (NIRD-HI)

NCT07338383
View directory record Official record
Conditions
Traumatic Brain Injury, Intracranial Hemorrhages, Combat Casualty Care, Point of Care
Interventions
NIRD-HI scan at the time of enrollment, Secondary NIRD-HI scan when a planned repeat CT is performed
Diagnostic Test
Lead sponsor
The Geneva Foundation
Other
Eligibility
18 Years to 89 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 2, 2026, 5:18 AM EDT
Recruiting Not applicable Interventional

Setting Families on a Positive Path to Recovery After Pediatric TBI: Road-to-Recovery

NCT05622461
View directory record Official record
Conditions
Traumatic Brain Injury, Head Injury, Head Injuries, Closed, Brain Hemorrhage, Traumatic, Brain Edema, Intracranial Edema
Interventions
Road-to-recovery
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Oct 2, 2026, 5:18 AM EDT
Withdrawn Early Phase 1 Interventional

Curcumin/Turmeric as a Treatment for Patients With Subdural Hematomas Recurrence

NCT03845322
View directory record Official record
Conditions
Hematoma, Subdural, Chronic
Interventions
Curcumin Pill, Placebo pills
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Oct 2, 2026, 5:18 AM EDT
Recruiting No phase listed Observational

Augmented Renal Clearance in Neurocritical Care

NCT07410624
View directory record Official record
Conditions
TBI (Traumatic Brain Injury), Status Epilepticus, Bacterial Meningitis, Augmented Renal Clearance (ARC), Subarachnoid Hemorrhage, Aneurysmal, Ischemic Stroke, Intracerebral Hemorrhage
Interventions
Not listed
Lead sponsor
University of Alberta
Other
Eligibility
18 Years to 85 Years
Enrollment
512 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Lexington, Kentucky • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 2, 2026, 5:18 AM EDT
Recruiting Not applicable Interventional

Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study

NCT06347796
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Conventional Surgery, Middle Meningeal Artery Embolization (MMAE)
Procedure · Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
40 Years to 90 Years
Enrollment
520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
31
States / cities
Phoenix, Arizona • Jacksonville, Florida • Miami, Florida + 26 more
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 2, 2026, 5:18 AM EDT
Completed Not applicable Interventional

Teen Online Problem Solving (TOPS) - An Online Intervention Following TBI

NCT00409058
View directory record Official record
Conditions
TBI (Traumatic Brain Injury), Brain Edema, Craniocerebral Trauma, Hematoma, Brain Concussion
Interventions
Teen Online Problem Solving
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
11 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
2
States / cities
Cincinnati, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 28, 2014 · Synced Oct 2, 2026, 5:18 AM EDT
Recruiting No phase listed Observational

Non-Invasive Monitoring Methods in Patients With Acute Brain Injury

NCT06504238
View directory record Official record
Conditions
Brain Injury, Acute
Interventions
Not listed
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
720 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 2, 2026, 5:18 AM EDT
Recruiting Phase 1Phase 2 Interventional

Chronic Subdural Hematoma Treatment With Intra-Arterial Bevacizumab Injection

NCT06510582
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Bevacizumab 2 mg/kg, Bevacizumab 4 mg/kg
Drug
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Oct 2, 2026, 5:18 AM EDT
Not listed Not applicable Interventional

Augmented Reality for Subdural Drain Placement

NCT06052124
View directory record Official record
Conditions
Subdural Hematoma
Interventions
Augmented Reality Device
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2023 · Synced Oct 2, 2026, 5:18 AM EDT
Withdrawn Early Phase 1 Interventional

Targeting Spreading Depolarization After Chronic Subdural Hematoma Surgery (TASD)

NCT04966546
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Memantine Hydrochloride, Placebo
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 2, 2026, 5:18 AM EDT
Terminated Phase 4 Interventional Results available

Normoglycemia and Neurological Outcome

NCT01137773
View directory record Official record
Conditions
Acute, Non-traumatic Subarachnoid Hemorrhage, Intraparenchymal Hemorrhage, Brain Injuries
Interventions
Insulin, Conventional insulin treatment
Drug
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 80 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 4, 2022 · Synced Oct 2, 2026, 5:18 AM EDT
Completed Not applicable Interventional Results available

The SQUID Trial for the Embolization of the Middle Meningeal Artery for Treatment of Chronic Subdural Hematoma (STEM)

NCT04410146
View directory record Official record
Conditions
Subdural Hematoma, Chronic
Interventions
SQUID Embolization, SQUID Embolization and Surgical Evacuation, Surgical Evacuation, Standard Medical Management
Device · Procedure · Other
Lead sponsor
Balt USA
Industry
Eligibility
30 Years and older
Enrollment
319 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
25
States / cities
Phoenix, Arizona • Tucson, Arizona • Riverside, California + 21 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 2, 2026, 5:18 AM EDT
Enrolling by invitation No phase listed Observational

Platelet Transfusion and Repeat TEG-PM in Patients With Severe TBI on Antiplatelet Therapy (Repeat TEG-PM)

NCT06433622
View directory record Official record
Conditions
Traumatic Intracranial Hemorrhage
Interventions
Repeat Thromboelastography with Platelet Mapping
Diagnostic Test
Lead sponsor
Lancaster General Hospital
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Oct 2, 2026, 5:18 AM EDT
Recruiting Phase 2 Interventional

Autologous Adipose-Derived Mesenchymal Stem Cells for Chronic Traumatic Brain Injury

NCT05951777
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Autologous HB-adMSCs, Normal Saline
Biological · Drug
Lead sponsor
Hope Biosciences LLC
Industry
Eligibility
18 Years to 55 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Houston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 2, 2026, 5:18 AM EDT
Not listed Not applicable Interventional

Evaluate the SENSE Device's Ability to Monitor and Detect Intracranial Hemorrhage

NCT04642443
View directory record Official record
Conditions
Intracranial Hemorrhages, Traumatic Brain Injury
Interventions
SENSE Device
Device
Lead sponsor
Sense Diagnostics, LLC
Industry
Eligibility
22 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 2, 2026, 5:18 AM EDT
Completed No phase listed Observational

SAFETY: Stabilization Points to Third Hospital Line Assessment oF the Impact of the usE of Infrascanner Model 2500 to Provide Decision Support for Diagnosis/Screening of Traumatic Brain InjurY in Ukraine

NCT07014748
View directory record Official record
Conditions
Traumatic Brain Hemorrhage
Interventions
Handheld brain hematoma detector
Diagnostic Test
Lead sponsor
InfraScan, Inc.
Industry
Eligibility
Not listed
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 2, 2026, 5:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Factors Influencing Readmission Rates of Acute Traumatic Subdural Hematoma in the Elderly

NCT03878043
View directory record Official record
Conditions
Traumatic Subdural Hematoma
Interventions
Follow-up Care
Other
Lead sponsor
Tarik Wasfie, MD
Industry
Eligibility
18 Years to 105 Years
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Grand Blanc, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Oct 2, 2026, 5:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

In-Field Detection of Intracranial Pressure

NCT04515212
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Optic Nerve Ultrasounds
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 99 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Oct 2, 2026, 5:18 AM EDT
Completed Phase 2 Interventional Results available

Temozolomide (TMZ) In Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST)

NCT03556384
View directory record Official record
Conditions
Gastrointestinal Stromal Tumors, Sdh, GIST, Cancer
Interventions
Temozolomide
Drug
Lead sponsor
Adam Burgoyne, MD, PhD
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
4
States / cities
La Jolla, California • Miami, Florida • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 2, 2026, 5:18 AM EDT
Completed Phase 4 Interventional Results available

A Study on the Safety of Tranexamic Acid for the Chronic Subdural Hematoma Population

NCT02618382
View directory record Official record
Conditions
Subdural Hematoma
Interventions
Tranexamic Acid
Drug
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years to 85 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 11, 2021 · Synced Oct 2, 2026, 5:18 AM EDT
Completed Not applicable Interventional

Embolization of the Middle Meningeal Artery With ONYX™ Liquid Embolic System for Subacute and Chronic Subdural Hematoma

NCT04402632
View directory record Official record
Conditions
Subdural Hematoma
Interventions
Surgical Management, Onyx™ Liquid Embolic System (LES) Embolization, Observation Only
Procedure · Device · Other
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
18 Years to 90 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
49
States / cities
Birmingham, Alabama • Tucson, Arizona • Irvine, California + 44 more
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Oct 2, 2026, 5:18 AM EDT
Not yet recruiting No phase listed Observational

Prospective Observational Multimodal Neuromonitoring in Adult NSICU Patients

NCT07577713
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Aneurysmal, Brain Injuries, Traumatic, Cerebral Hemorrhage, Ischemic Stroke, Delayed Emergence From Anesthesia, Encephalopathy
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 2, 2026, 5:18 AM EDT