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Showing 25–48 of 69 matching trials from the live ClinicalTrials.gov search.
Conditions
Tricuspid Valve Regurgitation, Tricuspid Valve Disease, Cardiovascular Diseases (CVD), Heart Valve Diseases, Tricuspid Valve Insufficiency, Severe Heart Valve Disease, Randomized Controlled Trial (RCT), Symptomatic Tricuspid Regurgitation
Interventions
Transcatheter Tricuspid Valve Replacement (TTVR) with VDyne System, Transcatheter Tricuspid Valve Replacement (TTVR) with Edwards EVOQUE System
Device
Lead sponsor
VDyne, Inc.
Industry
Eligibility
18 Years and older
Enrollment
730 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2036
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Cardiac Valve Disease
Interventions
Not listed
Lead sponsor
Corcym S.r.l
Industry
Eligibility
Not listed
Enrollment
2,150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2035
U.S. locations
9
States / cities
Indianapolis, Indiana • New Orleans, Louisiana • Portland, Maine + 5 more
Conditions
Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases
Interventions
DUO Transcatheter Tricuspid Coaptation Valve System
Device
Lead sponsor
CroiValve Limited
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
13
States / cities
Phoenix, Arizona • Thousand Oaks, California • Atlanta, Georgia + 10 more
Conditions
Tricuspid Regurgitation
Interventions
Heterotopic Implantation Of the Edwards-Sapien XT Transcatheter Valve in the Inferior VEna Cava
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
22 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Tricuspid Regurgitation (TR)
Interventions
TTVI with LuX-Valve Plus System, TTVI with EVOQUE
Device
Lead sponsor
Jenscare Innovation Inc.
Industry
Eligibility
21 Years and older
Enrollment
680 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2038
U.S. locations
2
States / cities
Naples, Florida • The Bronx, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

CorMatrix Cor TRICUSPID ECM Valve Replacement Study

NCT02397668
Conditions
Tricuspid Valve Disease
Interventions
CorMatrix Cor TRICUSPID ECM Valve
Device
Lead sponsor
Corvivo Cardiovascular, Inc.
Industry
Eligibility
1 Year to 85 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
4
States / cities
Mobile, Alabama • Indianapolis, Indiana • Baltimore, Maryland + 1 more
Conditions
Tricuspid Valve Regurgitation, Non-rheumatic, Mitral Valve Regurgitation
Interventions
Not listed
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
Not listed
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Recruiting No phase listed Observational

TriClip CED RWE Study

NCT06920745
Conditions
Tricuspid Regurgitation
Interventions
The TriClip System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
2,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
1
States / cities
Santa Clara, California
Conditions
Fontan Procedure, Hypoplastic Left Heart Syndrome, Tricuspid Atresia, Double Inlet Left Ventricle
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
10 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
San Francisco, California
Conditions
Tricuspid Regurgitation, Heart Failure, Structural Heart Disease, Interventional Cardiology
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
New York, New York
Conditions
Valvular Heart Disease
Interventions
HBCR hands-off, HBCR interactive
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Tricuspid Regurgitation, Tricuspid Regurgitation Functional
Interventions
Trillium™
Device
Lead sponsor
Innoventric LTD
Industry
Eligibility
18 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
9
States / cities
Thousand Oaks, California • Detroit, Michigan • Rochester, Minnesota + 6 more
Conditions
Mitral Regurgitation, Tricuspid Regurgitation, Valvular Heart Disease
Interventions
Abbott SJM Rigid Saddle Ring, Abbott SJM Séguin Ring, Abbott SJM Tailor Ring, Abbott SJM Tailor Band
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2031
U.S. locations
2
States / cities
Durham, North Carolina • Madison, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers

Effect of PEEP on TRJV in Mechanically Intubated Pediatric Patients

NCT06229886
Conditions
Tricuspid Regurgitation, Mechanical Ventilation Pressure High, Pediatric Respiratory Diseases
Interventions
Application of positive-end-expiratory pressure
Other
Lead sponsor
Northwell Health
Other
Eligibility
3 Months to 18 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
New Hyde Park, New York
Conditions
Tricuspid Regurgitation
Interventions
Transcatheter Tricuspid Valve Replacement
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
9
States / cities
Phoenix, Arizona • Wichita, Kansas • Hackensack, New Jersey + 5 more
Completed No phase listed Observational Accepts healthy volunteers

Biomarkers in Aortic Stenosis - B.A.S.S.

NCT01334801
Conditions
Aortic Stenosis, Disorder of Prosthetic Cardiac Valve, Aortic Valve Insufficiency, Mitral Valve Insufficiency, Hypertrophic Cardiomyopathy, Tricuspid Valve Insufficiency
Interventions
Blood Draw
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
378 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2020
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Tricuspid Regurgitation
Interventions
Surgery or Transcatheter tricuspid valve intervention
Procedure
Lead sponsor
Ottawa Heart Institute Research Corporation
Other
Eligibility
18 Years and older
Enrollment
3,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Rochester, Minnesota • New York, New York
Conditions
Tricuspid Valve Disease, Tricuspid Regurgitation
Interventions
Prehabilitation
Other
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Plano, Texas
Conditions
Tricuspid Valve Insufficiency
Interventions
Tricuspid Valve Repair System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 90 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
4
States / cities
Los Angeles, California • Detroit, Michigan • Minneapolis, Minnesota + 1 more
Active, not recruiting Not applicable Interventional Results available

2019-06 TRISCEND Study

NCT04221490
Conditions
Tricuspid Valve Regurgitation, Heart Valve Diseases, Cardiovascular Diseases
Interventions
Transcatheter Tricuspid Valve Replacement
Device
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
18 Years and older
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
14
States / cities
Los Angeles, California • Stanford, California • Atlanta, Georgia + 9 more
Conditions
Dilated Cardiomyopathy, Tricuspid Atresia
Interventions
Methacetin Breath Test (MBT)
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Chronic Symptomatic Functional Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Heart Valve Disease
Interventions
Mitralign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS)
Device
Lead sponsor
Mitralign, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
11
States / cities
Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 8 more
Recruiting No phase listed Observational

DELINEATE-Prospective

NCT07197736
Conditions
Valve Disease, Aortic, Mitral Regurgitation (MR), Aortic Stenosis, Valvular Heart Disease, Tricuspid Regurgitation (TR), Aortic Regurgitation
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Completed No phase listed Observational

The Bronx-Valve Registry

NCT05453526
Conditions
Valvular Heart Disease
Interventions
Not listed
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
330,570 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
The Bronx, New York