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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:54 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Umbilical Hernia Clear all

Conditions: Umbilical Hernia
Interventions: Bupivacaine; Drug
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: Not listed
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Gastrointestinal Complication, Intestinal Obstruction, Gastroschisis, Hirschsprung Disease, Omphalocele, Midgut Volvulus
Interventions: Standard of Care, Exclusive Human Milk; Dietary Supplement
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 0 Days to 55 Years
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Umbilical Hernia
Interventions: Bupivacaine; Drug
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 5 Years to 17 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Mucopolysaccharidosis (MPS)
Interventions: Not listed
Lead sponsor: Shire; Industry
Eligibility: Up to 7 Years · Male only
Enrollment: 159 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 7
States / cities: Los Angeles, California • Jacksonville, Florida • Minneapolis, Minnesota + 4 more

Conditions: Umbilical Hernia
Interventions: Deflux; Device
Lead sponsor: South Shore Hospital; Other
Eligibility: 1 Year to 5 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: South Weymouth, Massachusetts

Conditions: Congenital Diaphragmatic Hernia
Interventions: Congenital diaphragmatic hernia resuscitation with an intact umbilical cord; Procedure
Lead sponsor: University of Colorado, Denver; Other
Eligibility: Up to 5 Minutes
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Umbilical Hernia
Interventions: Infra-umbilical incision, Transumbilical incision; Procedure
Lead sponsor: Children's Mercy Hospital Kansas City; Other
Eligibility: Up to 9 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Umbilical Hernia, Ventral Hernia
Interventions: Duramesh, Mesh; Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Pain
Interventions: rectus sheath block, local anesthetic infiltration; Procedure
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 1 Year to 17 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Umbilical Hernia, Ventral Hernia
Interventions: transvaginal NOTES ventral hernia repair; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2019
U.S. locations: 1
States / cities: San Diego, California

Conditions: Ventral Hernia, Umbilical Hernia, Incisional Hernia, Postoperative Complications, Pain, Postoperative
Interventions: Transabdominal Plane Block, Non Transabdominal Plane Block; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 127 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Umbilical Hernia, Obesity
Interventions: TAPB Group, RSB Group, conversion to general anesthesia; Procedure
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 99 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Postoperative Pain
Interventions: Intravenous Ibuprofen, IV Placebo; Drug · Other
Lead sponsor: St. Barnabas Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Livingston, New Jersey

Conditions: Incisional Hernia, Ventral Hernia, Umbilical Hernia
Interventions: smoking cessation, tighter diabetic control, diet and exercise program; Behavioral
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Congenital Diaphragmatic Hernia
Interventions: Autologous umbilical cord blood; Biological
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 10 Minutes to 7 Days
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Pediatric Postoperative Pain
Interventions: bilateral ultrasound-guided rectus sheath block, Wound infiltration; Procedure
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 3 Years to 12 Years
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 2
States / cities: Boston, Massachusetts • Waltham, Massachusetts

Conditions: Hernia, Postoperative Pain
Interventions: 5x5cm bupivacaine collagen sponges; Drug
Lead sponsor: Innocoll; Industry
Eligibility: 18 Years and older · Male only
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 1
States / cities: Bellaire, Texas

Conditions: Pain, Postoperative
Interventions: Pre-op percutaneous rectus sheath block, Intra-operative rectus sheath block, Ropivacaine; Procedure · Drug
Lead sponsor: Johns Hopkins All Children's Hospital; Other
Eligibility: 3 Years to 18 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: St. Petersburg, Florida

Conditions: Ventral Hernia, Umbilical Hernia, Epigastric Hernia
Interventions: Ventral Hernia Repair; Procedure
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Cleveland, Ohio

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Caudal Versus Rectus Sheath Study

The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies

Analgesic Efficacy After Umbilical Hernia Repair in Children

Mucopolysaccharidosis (MPS) I, II, and VI Screening in a High-Risk Population With Previous Surgical Repair or Presence of Inguinal and/or Umbilical Hernia in Combination With Pediatric ENT Surgery (The HATT Project)

Minimally Invasive Closure of Umbilical Hernias

Resuscitation of Infants With Congenital Diaphragmatic Hernia With an Intact Umbilical Cord

Cosmetic Outcomes of Umbilical Hernia Incisions

Duramesh Versus Minimally Invasive IPOM for High-Risk Umbilical Hernia Repairs

Ultrasound-guided Rectus Sheath Block for Post-operative Pain Control Following Umbilical Hernia Repair

Natural Orifice Translumenal Endoscopic Surgery (NOTES): Laparoscopic Assisted Transvaginal Ventral Hernia Repair

Does a Transabdominal Plane Block Decrease Patient Pain After Ventral Hernia Repair?

Abdominal Wall Block Study

Does Preoperative Caldolor Decrease the Requirement for Postoperative Narcotics

Watchful Waiting of Incisional Hernias

Umbilical Cord Blood Mononuclear Cells for Hypoxic Neurologic Injury in Infants With Congenital Diaphragmatic Hernia (CDH)

Postoperative Pain After Pediatric Umbilical Hernia Repair

Assess the Feasibility and Efficacy of the CollaRx® Bupivacaine Implant Laparoscopic Inguinal or Umbilical Herniorrhaphy

Percutaneous Rectus Sheath Block Versus Intra-operative Rectus Sheath Block for Pediatric Umbilical Hernia Repair

Comparing eTEP and Laparoscopic Intraperitoneal Onlay Mesh (IPOM) for Ventral Hernias