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ClinicalTrials.gov public records Last synced Sep 13, 2026, 9:29 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Upper Extremity Paralysis Clear all
Completed Not applicable Interventional Results available

Therapies for Recovery of Hand Function After Stroke

NCT03574623
View directory record Official record
Conditions
Stroke, Upper Extremity Paresis, Hemiplegia
Interventions
Electrical Stimulator, Occupational Therapy
Device · Behavioral
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 90 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
4
States / cities
Atlanta, Georgia • Baltimore, Maryland • West Orange, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Sep 13, 2026, 9:29 PM EDT
Not yet recruiting Not applicable Interventional

Using Power Mobility Training to Promote Arm & Hand Function in Children With Cerebral Palsy

NCT07342348
View directory record Official record
Conditions
Cerebral Palsy, Hemiplegia, Infantile
Interventions
Arm- and hand-use focused power mobility training
Other
Lead sponsor
Grand Valley State University
Other
Eligibility
3 Years to 8 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2028 – 2029
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 13, 2026, 9:29 PM EDT
Completed Not applicable Interventional

Feasibility of Pediatric CIMT by Televideo

NCT05303883
View directory record Official record
Conditions
Hemiplegic Cerebral Palsy
Interventions
Pediatric Constrained Induced Movement Therapy
Other
Lead sponsor
Ohio State University
Other
Eligibility
1 Year to 10 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Columbus, Ohio • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Sep 13, 2026, 9:29 PM EDT
Completed Phase 3 Interventional Results available

Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Arm(s) or of Arm(s) and Leg(s) in Cerebral Palsy

NCT02002884
View directory record Official record
Conditions
Cerebral Palsy, Spasticity
Interventions
IncobotulinumtoxinA (8 Units per kg body weight), IncobotulinumtoxinA (6 Units per kg body weight), IncobotulinumtoxinA (2 Units per kg body weight)
Drug
Lead sponsor
Merz Pharmaceuticals GmbH
Industry
Eligibility
2 Years to 17 Years
Enrollment
351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
6
States / cities
Gulf Breeze, Florida • Loxahatchee Groves, Florida • Savannah, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Sep 13, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

Treatment of Chronic Stroke With AMES + EMG Biofeedback

NCT01116544
View directory record Official record
Conditions
Stroke, Plegia, Paresis, Cerebrovascular Accident
Interventions
AMES Therapy (assisted movement and enhanced sensation)
Device
Lead sponsor
AMES Technology
Industry
Eligibility
18 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
3
States / cities
Atlanta, Georgia • Chicago, Illinois • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 17, 2019 · Synced Sep 13, 2026, 9:29 PM EDT
Recruiting Not applicable Interventional

Utility of CC7 Transfer in Stroke Subtypes

NCT06001736
View directory record Official record
Conditions
Stroke, Ischemic, Stroke Hemorrhagic, Spastic Hemiparesis
Interventions
Contralateral C7 root transfer for the treatment of spastic hemiparesis.
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 13, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

Investigating the Effect of Stochastic Resonance Vibration on Gait and Balance and Upper Extremity Function in Children With Cerebral Palsy

NCT04388787
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Stochastic resonance (SR) wraps
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
3 Years to 18 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 17, 2022 · Synced Sep 13, 2026, 9:29 PM EDT
Not yet recruiting Not applicable Interventional

Feasibility of Home Based Transcutaneous Spinal Cord Stimulation for Persons With SCI

NCT06140706
View directory record Official record
Conditions
Tetraplegia
Interventions
transcutaneous Spinal Cord Stimulation (tSCS)
Behavioral
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Sep 13, 2026, 9:29 PM EDT
Not listed Not applicable Interventional

Adaptive Arm Training for Children With Hemiplegia

NCT03387449
View directory record Official record
Conditions
Cerebral Palsy, Hemiplegia, Hemiparesis, Acquired Brain Injury
Interventions
Bimanual Arm Training
Device
Lead sponsor
Blythedale Children's Hospital
Other
Eligibility
5 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Hartsdale, New York
Source: ClinicalTrials.gov public record
Updated Jan 9, 2022 · Synced Sep 13, 2026, 9:29 PM EDT
Completed Not applicable Interventional

Mechanisms of Arm Recovery in Stroke Patients With Hand Paralysis

NCT03067818
View directory record Official record
Conditions
Stroke, Hemiparesis, Cerebral Vascular Accident, Stroke, Ischemic
Interventions
Unaffected Transcranial Magnetic Stimulation, Affected Transcranial Magnetic Stimulation, Control Transcranial Magnetic Stimulation
Procedure
Lead sponsor
George Mason University
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Sep 13, 2026, 9:29 PM EDT
Completed Phase 1Phase 2 Interventional Results available

The Role of Trans-spinal Direct Current Stimulation (tsDCS) in Treating Patients With Hand Spasticity After Stroke

NCT03080454
View directory record Official record
Conditions
Stroke, Cerebrovascular Accident (CVA), Hemiparesis, Spasticity as Sequela of Stroke, Muscle Spasticity, Upper Extremity Paralysis
Interventions
sham Doublestim, anodal Doublestim
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 4, 2021 · Synced Sep 13, 2026, 9:29 PM EDT
Not yet recruiting Not applicable Interventional

Virtual Activities of Living for Occupational Rehabilitation

NCT07450586
View directory record Official record
Conditions
Stroke, Occupational Therapy, Activities of Daily Living, Rehabilitation, Virtual Reality
Interventions
VALOR Home Exercise Program (HEP), Usual Care Treatment (UCT) Control
Device · Other
Lead sponsor
Barron Associates, Inc.
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Sep 13, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

Use of Joystick-operated Ride-on-toys to Improve Affected Arm Use and Function in Children With Hemiplegic Cerebral Palsy

NCT05559320
View directory record Official record
Conditions
Hemiplegic Cerebral Palsy
Interventions
Ride-on-toy navigation training, Upper extremity functional training
Device · Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
3 Years to 8 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 16, 2025 · Synced Sep 13, 2026, 9:29 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Behavioral Assessment Method Index

NCT07291479
View directory record Official record
Conditions
Infant Development, Perinatal Stroke, Hemiparesis, Cerebral Palsy
Interventions
Non interventional study
Other
Lead sponsor
Ohio State University
Other
Eligibility
4 Months to 36 Months
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 13, 2026, 9:29 PM EDT
Active, not recruiting No phase listed Observational

Nerve Transfer After Spinal Cord Injury- Multi-center

NCT04023591
View directory record Official record
Conditions
Tetraplegia, Spinal Cord Injuries, Quadriplegia Flaccid
Interventions
Surgery/Occupational Therapy
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
7
States / cities
Stanford, California • Miami, Florida • Ann Arbor, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 13, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

Constraint-induced Movement Therapy (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegic Cerebral Palsy

NCT00305006
View directory record Official record
Conditions
Cerebral Palsy, Hemiplegia, Children, Pediatric
Interventions
Constraint-Induced Movement Therapy (CIMT), Hand-Arm Bimanual Intensive Therapy (HABIT)
Procedure
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
30 Months to 14 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2021 · Synced Sep 13, 2026, 9:29 PM EDT
Completed Early Phase 1 Interventional Results available

CIMT and taVNS for Hemiplegia in Infants

NCT05101707
View directory record Official record
Conditions
Infant Development, Hemiplegia, Constraint Induced Movement Therapy
Interventions
transcutaneous auricular vagus nerve stimulation, Constraint induced movement therapy
Device · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
6 Months to 18 Months
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Sep 13, 2026, 9:29 PM EDT
Completed Not applicable Interventional

A Pilot Study Investigating the Feasibility of the Saebo Arm Training Program on an Inpatient Population

NCT00489580
View directory record Official record
Conditions
Stroke, Hemiplegia
Interventions
SaeboFlex Dynamic Hand Orthosis, Saebo F.T.M. Arm Training Program
Device · Procedure
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
East Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 24, 2007 · Synced Sep 13, 2026, 9:29 PM EDT
Completed Phase 2 Interventional Results available

Post Stroke Hand Functions: Bilateral Movements and Electrical Stimulation Treatments

NCT00369668
View directory record Official record
Conditions
Cerebrovascular Accident, Hemiplegia
Interventions
Bilateral movements and neuromuscular electrical stimulation, Bilateral movements and sham electrical stimulation
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
44 Years to 86 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 14, 2012 · Synced Sep 13, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

Passive Tactile Stimulation for Stroke Rehabilitation

NCT03814889
View directory record Official record
Conditions
Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Spasticity as Sequela of Stroke
Interventions
Vibration pattern, No vibration
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2024 · Synced Sep 13, 2026, 9:29 PM EDT
Active, not recruiting Not applicable Interventional

Hand-Arm Bimanual Intensive Therapy in Virtual Reality Versus Standard Hand-Arm Bimanual Intensive Therapy

NCT05867368
View directory record Official record
Conditions
Hemiplegic Cerebral Palsy
Interventions
HABIT-VR, Standard HABIT
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
6 Years to 16 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 13, 2026, 9:29 PM EDT
Enrolling by invitation Not applicable Interventional

Control of Assistive Devices Via Brain-Computer Interface Technology

NCT06710626
View directory record Official record
Conditions
Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS), Quadriplegia, Spinal Cord Injury (SCI), Spinal Cord Injury Cervical
Interventions
Assistive Robotic Arm
Device
Lead sponsor
Neuralink Corp
Industry
Eligibility
Not listed
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 13, 2026, 9:29 PM EDT
Completed Not applicable Interventional

Camp High 5: Evaluation of the Effect on Upper Limb Function

NCT02875054
View directory record Official record
Conditions
Neurological Injury, Hemiplegia
Interventions
Constraint induced movement therapy (CIMT), Hand-arm bimanual intensive training (HABIT)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
2 Years to 12 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Sep 13, 2026, 9:29 PM EDT
Recruiting Not applicable Interventional

tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia

NCT05866003
View directory record Official record
Conditions
Stroke, Upper Extremity Paresis, Hemiplegia
Interventions
Active conventional tDCS montage plus CCFES, Active unconventional tDCS montage plus CCFES, Sham tDCS plus CCFES, CCFES with Occupational Therapy
Device · Behavioral
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 90 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 13, 2026, 9:29 PM EDT