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Showing 1–24 of 105 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Upper Extremity Paresis Clear all
Recruiting Not applicable Interventional

The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.

NCT06765642
View directory record Official record
Conditions
Stroke, Stroke Patients, Arm Weakness as a Consequence of Stroke, Brain Stimulation, Transcranial Magnetic Stimulation Repetitive, Transcranial Magnetic Stimulation, Motor Learning, Chronic Stroke Patients, Chronic Stroke Survivors
Interventions
Transcranial Magnetic Stimulation
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Phase 2 Interventional Results available

Transcutaneous Vagus Nerve Stimulation (tVNS) and Robotic Training to Improve Arm Function After Stroke

NCT03592745
View directory record Official record
Conditions
Stroke, Cerebrovascular Accident (CVA), Hemiparesis
Interventions
Transcutaneous Vagus Nerve Stimulation (tVNS), Sham Transcutaneous Vagus Nerve Stimulation (tVNS)
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 85 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Jul 23, 2026, 7:02 AM EDT
Terminated Phase 1Phase 2 Interventional

Transcutaneous Vagus Nerve Stimulation for Motor Recovery After Stroke

NCT03292159
View directory record Official record
Conditions
Stroke, Upper Extremity Paresis
Interventions
Active RAVANS concurrent with arm motor training, Inactive RAVANS concurrent with arm motor training
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 20, 2021 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

TheraBracelet Phase I

NCT03318341
View directory record Official record
Conditions
Hand Function, Stroke, Upper Extremity, Hemiparesis, Cerebrovascular Accident, Stroke Rehabilitation
Interventions
Real Stimulation, Sham Stimulation
Device
Lead sponsor
TheraBracelet, Inc.
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 6, 2019 · Synced Jul 23, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional

Passive Robots for Stroke Rehabilitation: A Feasibility Study

NCT07218276
View directory record Official record
Conditions
Stroke
Interventions
Functional Training with SepaRRo and NeuRRoFES
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 75 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Motor Learning for Upper Limb Hemiparesis After Stroke

NCT05765474
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Practice Variable, No Practice Variable
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
40 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Jul 23, 2026, 7:02 AM EDT
Active, not recruiting Not applicable Interventional

Hand Rehabilitation Study for Stroke Patients

NCT03148106
View directory record Official record
Conditions
Upper Extremity Paresis, Disability Physical, Chronic Stroke, Motor Disorders
Interventions
Somatosensory Electrical Stimulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 24, 2025 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

Application of a Reimbursable Form of Constraint-Induced Movement Therapy for Upper Extremity

NCT05311384
View directory record Official record
Conditions
CVA (Cerebrovascular Accident), Stroke, Upper Extremity Paresis
Interventions
Keys Constraint-induced Movement Therapy protocol
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

Passive Tactile Stimulation for Stroke Rehabilitation

NCT03814889
View directory record Official record
Conditions
Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Spasticity as Sequela of Stroke
Interventions
Vibration pattern, No vibration
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2024 · Synced Jul 23, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional

tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia

NCT05866003
View directory record Official record
Conditions
Stroke, Upper Extremity Paresis, Hemiplegia
Interventions
Active conventional tDCS montage plus CCFES, Active unconventional tDCS montage plus CCFES, Sham tDCS plus CCFES, CCFES with Occupational Therapy
Device · Behavioral
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 90 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Non-invasive Trigeminal and Vagus Nerve Stimulation for Stroke Subjects With Chronic Upper Extremity Deficits

NCT06288217
View directory record Official record
Conditions
Upper Extremity Paresis, Stroke, Chronic
Interventions
NeuraStasis Stimulator System (Non-Invasive Trigeminal and Vagus Nerve Stimulation), Upper Limb Rehabilitation, Sham Stimulation
Device · Other
Lead sponsor
NeuraStasis, Inc
Industry
Eligibility
30 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Smartwatch App for Vibration Stimulation

NCT04050917
View directory record Official record
Conditions
Stroke, Physical Disability
Interventions
real stimulation, no stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

Contralaterally Controlled FES of Arm & Hand for Subacute Stroke Rehabilitation

NCT01688856
View directory record Official record
Conditions
Stroke, Hemiparesis, Hemiplegia
Interventions
Electrical Stimulator
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 8, 2020 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Not applicable Interventional

National Fully Remote Use of IpsiHand Device in Hemiparetic Stroke

NCT05965713
View directory record Official record
Conditions
Stroke, Hemiparesis, Spasticity as Sequela of Stroke, Brain Computer Interface
Interventions
Neurolutions IpsiHand System, Standard of Care - Home Exercise Program for Upper Extremity
Device · Other
Lead sponsor
Neurolutions, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

Robotic Brace Incorporating Electromyography for Moderate Affected Arm Impairment After Stroke

NCT01654315
View directory record Official record
Conditions
Hemiparesis
Interventions
Myomo Robotic Arm, RTP Standard Therapy
Device · Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
35 Years to 85 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 6, 2022 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

Neuroplasticity With Daily Use of a Sensorimotor Priming Vibration System to Improve Hand Function After Stroke

NCT04026399
View directory record Official record
Conditions
Stroke, Physical Disability
Interventions
peripheral vibration stimulation, therapy
Other · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 22, 2021 · Synced Jul 23, 2026, 7:02 AM EDT
Active, not recruiting Not applicable Interventional

Targeted Plasticity Therapy for Upper Limb Rehabilitation in Spinal Cord Injuries

NCT04288245
View directory record Official record
Conditions
Spinal Cord Injuries, Upper Extremity Paresis
Interventions
Active Vagus Nerve Stimulation, Placebo Vagus Nerve Stimulation
Device
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 64 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 23, 2026, 7:02 AM EDT
Not yet recruiting Not applicable Interventional

kTMP in Chronic Stroke

NCT07277595
View directory record Official record
Conditions
Stroke, Chronic Stroke Patients, Arm Weakness as a Consequence of Stroke
Interventions
kTMP sham stimulation 9 weeks + active stimulation 9 weeks, kTMP 18 weeks
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Physical and Mental Practice for Bimanual Coordination Rehabilitation

NCT03817086
View directory record Official record
Conditions
Traumatic Brain Injury, Weakness, Muscle, Coordination Impairment
Interventions
Hand coordination and mental practice, Hand coordination and action observation
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
20 Years to 60 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 13, 2022 · Synced Jul 23, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional

rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke

NCT03870672
View directory record Official record
Conditions
Stroke, Hemiplegia, Cerebrovascular Accident (CVA), Hemiparesis
Interventions
Contralaterally Controlled Functional Electrical Stimulation, New rTMS approach, Conventional rTMS approach, Sham rTMS approach
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Study of the Recovery of Muscle Function in the Arm/Hand After a Stroke

NCT01422005
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Simultaneous Bimanual training, Conventional Occupational Therapy
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 75 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2020 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

Utilizing Gaming Mechanics to Optimize Telerehabilitation Adherence in Persons With Stroke

NCT03985761
View directory record Official record
Conditions
Stroke
Interventions
Home Telerehabilitation using HoVRS
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
40 Years to 80 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Remediation of the Non-Paretic Arm in Stroke

NCT03062930
View directory record Official record
Conditions
Stroke
Interventions
Track 1, Track 2
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 27, 2019 · Synced Jul 23, 2026, 7:02 AM EDT
Completed Early Phase 1 Interventional Results available

CIMT and taVNS for Hemiplegia in Infants

NCT05101707
View directory record Official record
Conditions
Infant Development, Hemiplegia, Constraint Induced Movement Therapy
Interventions
transcutaneous auricular vagus nerve stimulation, Constraint induced movement therapy
Device · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
6 Months to 18 Months
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Jul 23, 2026, 7:02 AM EDT