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Showing 1–24 of 55 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Upper Extremity Weakness Clear all
Completed Not applicable Interventional Results available

Application of a Reimbursable Form of Constraint-Induced Movement Therapy for Upper Extremity

NCT05311384
View directory record Official record
Conditions
CVA (Cerebrovascular Accident), Stroke, Upper Extremity Paresis
Interventions
Keys Constraint-induced Movement Therapy protocol
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Jul 22, 2026, 12:49 AM EDT
Withdrawn Phase 2 Interventional

RCT of a Neuroplasticity Agent and CI Therapy for Severe Arm Paresis After Stroke

NCT01963832
View directory record Official record
Conditions
Severe Stroke With Affected Arm Motor Function
Interventions
Fluoxetine, Placebo, eCMIT, Usual Care
Drug · Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
40 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 11, 2015 · Synced Jul 22, 2026, 12:49 AM EDT
Terminated Not applicable Interventional Results available

Brain Stimulation and Rehabilitation for Adults With Chronic, Severe Arm Motor Impairment After Stroke

NCT03538795
View directory record Official record
Conditions
Stroke, Hemiplegia, Hemiparesis
Interventions
iTBS&eCIMT
Combination Product
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 20, 2020 · Synced Jul 22, 2026, 12:49 AM EDT
Not listed Not applicable Interventional

Mental Practice Protocol With Severe Upper Extremity Hemiparesis

NCT05519306
View directory record Official record
Conditions
Stroke, Upper Extremity Paresis
Interventions
Mental Practice
Behavioral
Lead sponsor
Adventist HealthCare
Other
Eligibility
18 Years to 90 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 6, 2022 · Synced Jul 22, 2026, 12:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis

NCT00125658
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
Control, Experimental
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 22, 2017 · Synced Jul 22, 2026, 12:49 AM EDT
Recruiting Not applicable Interventional

Pilot/Pivotal Study of DBS+Rehab After Stroke

NCT05701280
View directory record Official record
Conditions
Stroke, Upper Extremity Paresis
Interventions
Deep Brain Stimulation, Rehabilitation
Device · Other
Lead sponsor
Enspire DBS Therapy, Inc.
Industry
Eligibility
21 Years and older
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
10
States / cities
Phoenix, Arizona • Jacksonville, Florida • Baltimore, Maryland + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Jul 22, 2026, 12:49 AM EDT
Completed Not applicable Interventional

Wearable Robotic Functional Assistance for Stroke Rehabilitation

NCT00396708
View directory record Official record
Conditions
CVA (Cerebrovascular Accident)
Interventions
myomo e100 neurorobotic elbow brace
Device
Lead sponsor
Myomo
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 2, 2010 · Synced Jul 22, 2026, 12:49 AM EDT
Recruiting Not applicable Interventional

Passive Robots for Stroke Rehabilitation: A Feasibility Study

NCT07218276
View directory record Official record
Conditions
Stroke
Interventions
Functional Training with SepaRRo and NeuRRoFES
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 75 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Jul 22, 2026, 12:49 AM EDT
Not listed Not applicable Interventional

The Effect of Combined Armeospring and CIT on Neuro-motor and Functional Recovery in Children With Unilateral CP

NCT02914925
View directory record Official record
Conditions
Cerebral Palsy, Hemiplegia, Upper Extremity Weakness
Interventions
ArmeoSpring/CIT
Device
Lead sponsor
St Mary's Hospital for Children
Other
Eligibility
7 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Queens, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2016 · Synced Jul 22, 2026, 12:49 AM EDT
Completed Not applicable Interventional

The Application of a Mental Practice Protocol in the Acute Inpatient Rehabilitation Setting

NCT04927728
View directory record Official record
Conditions
Stroke, Upper Extremity Paresis
Interventions
Mental Practice, Repetitive-Task Practice, Traditional Therapy
Other
Lead sponsor
Adventist HealthCare
Other
Eligibility
18 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 15, 2021 · Synced Jul 22, 2026, 12:49 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

NCT04798378
View directory record Official record
Conditions
Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies, Arthrogryposis, Spinal Cord Injuries, Charcot-Marie-Tooth, Stroke, Weakness of Extremities as Sequela of Stroke, Weakness Due to Upper Motor Neuron Dysfunction, Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, Arm Paralysis, Cerebral Palsy
Interventions
Neurosleeve
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
4 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Wilmington, Delaware • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Jul 22, 2026, 12:49 AM EDT
Active, not recruiting Not applicable Interventional

Hand Rehabilitation Study for Stroke Patients

NCT03148106
View directory record Official record
Conditions
Upper Extremity Paresis, Disability Physical, Chronic Stroke, Motor Disorders
Interventions
Somatosensory Electrical Stimulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 24, 2025 · Synced Jul 22, 2026, 12:49 AM EDT
Recruiting Not applicable Interventional

tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia

NCT05866003
View directory record Official record
Conditions
Stroke, Upper Extremity Paresis, Hemiplegia
Interventions
Active conventional tDCS montage plus CCFES, Active unconventional tDCS montage plus CCFES, Sham tDCS plus CCFES, CCFES with Occupational Therapy
Device · Behavioral
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 90 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Jul 22, 2026, 12:49 AM EDT
Recruiting Not applicable Interventional

kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot

NCT07631078
View directory record Official record
Conditions
Stroke, Chronic Stroke Patients, Arm Weakness as a Consequence of Stroke
Interventions
kTMP, Sham kTMP
Device
Lead sponsor
Magnetic Tides
Industry
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Jul 22, 2026, 12:49 AM EDT
Terminated Phase 4 Interventional Results available

Does Low-does Cervical Epidural Lidocaine Cause Transient Weakness?

NCT03382925
View directory record Official record
Conditions
Cervical Radiculopathy
Interventions
cervical interlaminar with lidocaine, cervical interlaminar with normal saline, Lidocaine, Triamcinolone Acetonide, Normal saline
Procedure · Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 24, 2022 · Synced Jul 22, 2026, 12:49 AM EDT
Not listed Not applicable Interventional

Priming With tDCS: Expanding the Window of Recovery in Chronic Stroke

NCT03964467
View directory record Official record
Conditions
Upper Extremity Paresis
Interventions
transcranial direct current stimulation
Device
Lead sponsor
University of the Sciences in Philadelphia
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2023 · Synced Jul 22, 2026, 12:49 AM EDT
Completed Not applicable Interventional Results available

Synchronized Brain and Hand Stimulation After Stroke

NCT04502290
View directory record Official record
Conditions
Stroke, Upper Extremity Paresis
Interventions
Combined Non-invasive brain stimulation and functional electrical hand stimulation
Device
Lead sponsor
Amit Sethi
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Jul 22, 2026, 12:49 AM EDT
Completed No phase listed Observational

Bimanual Arm Training in Acute Stroke

NCT05106595
View directory record Official record
Conditions
Stroke, Acute, Upper Extremity Paresis
Interventions
Bimanual Arm Trainer
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Jul 22, 2026, 12:49 AM EDT
Terminated Not applicable Interventional Results available

Galvanic Vestibular Stimulation and Motor Training in Traumatic Brain Injury Survivors

NCT01749800
View directory record Official record
Conditions
TBI, Attention Deficits, Motor Impairments
Interventions
GVS, Sham GVS, Armeo Spring
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Jul 22, 2026, 12:49 AM EDT
Recruiting Not applicable Interventional

Personalized Transcranial Direct Current Stimulation in Stroke Recovery

NCT06286800
View directory record Official record
Conditions
Stroke, Chronic Stroke, Hemorrhage Brain, Ischemic Stroke
Interventions
Transcranial direct current stimulation (tDCS) with OT, Sham tDCS with OT
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Jul 22, 2026, 12:49 AM EDT
Terminated Phase 1Phase 2 Interventional

Transcutaneous Vagus Nerve Stimulation for Motor Recovery After Stroke

NCT03292159
View directory record Official record
Conditions
Stroke, Upper Extremity Paresis
Interventions
Active RAVANS concurrent with arm motor training, Inactive RAVANS concurrent with arm motor training
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 20, 2021 · Synced Jul 22, 2026, 12:49 AM EDT
Recruiting Not applicable Interventional

Utility of CC7 Transfer in Stroke Subtypes

NCT06001736
View directory record Official record
Conditions
Stroke, Ischemic, Stroke Hemorrhagic, Spastic Hemiparesis
Interventions
Contralateral C7 root transfer for the treatment of spastic hemiparesis.
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jul 22, 2026, 12:49 AM EDT
Recruiting Not applicable Interventional

Constraint-Induced Movement Therapy for Adults Post-Stroke With Mild Upper Extremity Impairment

NCT05492513
View directory record Official record
Conditions
CVA (Cerebrovascular Accident), Stroke, Upper Extremity Paresis
Interventions
Grade 1 CI Therapy +Sensory Components
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Jul 22, 2026, 12:49 AM EDT
Completed Not applicable Interventional Results available

Effects of a Compliant Arm Support on Post-stroke Upper Extremity Range of Motion

NCT03867838
View directory record Official record
Conditions
Arm Weakness as a Consequence of Stroke
Interventions
compliant support
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 22, 2021 · Synced Jul 22, 2026, 12:49 AM EDT