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ClinicalTrials.gov public records Last synced Oct 1, 2026, 10:50 PM EDT

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Showing 1–24 of 24 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Upper Limb Hemiparesis Following Stroke Clear all
Completed Not applicable Interventional

Repetitive Action Simulation Circuit Training to Reduce Arm Weakness After a Stroke

NCT07772284
View directory record Official record
Conditions
Stroke, Hemiparesis of the Upper Limb Following Stroke
Interventions
Upper Extremity Action Simulation Circuit Training
Other
Lead sponsor
Towson University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
2
States / cities
Towson, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 1, 2026, 10:50 PM EDT
Terminated Phase 2 Interventional

Investigation of Neural Stem Cells in Ischemic Stroke

NCT03629275
View directory record Official record
Conditions
Ischemic Stroke, Chronic Stroke, Hemiparesis, Arm Paralysis
Interventions
CTX0E03 Drug Product and delivery device, Placebo
Combination Product · Drug
Lead sponsor
ReNeuron Limited
Industry
Eligibility
35 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
23
States / cities
Little Rock, Arkansas • Irvine, California • Los Angeles, California + 19 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2021 · Synced Oct 1, 2026, 10:50 PM EDT
Completed Not applicable Interventional

Motor Learning for Upper Limb Hemiparesis After Stroke

NCT05765474
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Practice Variable, No Practice Variable
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
40 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 1, 2026, 10:50 PM EDT
Completed Not applicable Interventional Results available

Arm Rehabilitation Study After Stroke

NCT00871715
View directory record Official record
Conditions
Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction, Cerebrovascular Disorders
Interventions
Accelerated Skill Acquisition Program (ASAP), Dose-Equivalent Usual & Customary Care - DEUCC, Usual and Customary Care - UCC
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
21 Years and older
Enrollment
361 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
8
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Oct 1, 2026, 10:50 PM EDT
Recruiting Not applicable Interventional

Transcutaneous Electrical Stimulation for Stroke Patients

NCT06950593
View directory record Official record
Conditions
Upper Limb Hemiparesis Following Stroke
Interventions
Task Specific Training (TST), Transcutaneous electrical spinal cord stimulation (TESS), Sham transcutaneous electrical spinal cord stimulation (Sham TESS)
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Oct 1, 2026, 10:50 PM EDT
Completed Not applicable Interventional Results available

Fatiguing Arm Exercise Following Stroke

NCT03194464
View directory record Official record
Conditions
Stroke
Interventions
submaximal exercise (grip)
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Oct 1, 2026, 10:50 PM EDT
Completed Not applicable Interventional Results available

Visual Feedback Therapy for Treating Individuals With Hemiparesis Following Stroke

NCT01662960
View directory record Official record
Conditions
Hemiparesis, Stroke
Interventions
Mirror therapy, Divider therapy
Behavioral
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
21 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 30, 2020 · Synced Oct 1, 2026, 10:50 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Critical Periods After Stroke Study (CPASS)

NCT02235974
View directory record Official record
Conditions
Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction, Cerebrovascular Disorders
Interventions
Early Intensive upper extremity motor training, Sub-acute intensive upper extremity motor training, Chronic intensive upper extremity motor training, Control
Behavioral
Lead sponsor
MedStar National Rehabilitation Network
Other
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 1, 2026, 10:50 PM EDT
Completed Phase 1Phase 2 Interventional Results available

The Role of Trans-spinal Direct Current Stimulation (tsDCS) in Treating Patients With Hand Spasticity After Stroke

NCT03080454
View directory record Official record
Conditions
Stroke, Cerebrovascular Accident (CVA), Hemiparesis, Spasticity as Sequela of Stroke, Muscle Spasticity, Upper Extremity Paralysis
Interventions
sham Doublestim, anodal Doublestim
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 5, 2021 · Synced Oct 1, 2026, 10:50 PM EDT
Suspended Not applicable Interventional

Improving Arm Function Using Wearable Exoskeletons

NCT05951491
View directory record Official record
Conditions
Hemiparesis; Poststroke/CVA
Interventions
Wearable Shoulder Exoskeleton, Wearable Hand Exoskeleton
Device
Lead sponsor
University of Idaho
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Moscow, Idaho
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 1, 2026, 10:50 PM EDT
Completed Phase 2 Interventional Results available

Transcutaneous Vagus Nerve Stimulation (tVNS) and Robotic Training to Improve Arm Function After Stroke

NCT03592745
View directory record Official record
Conditions
Stroke, Cerebrovascular Accident (CVA), Hemiparesis
Interventions
Transcutaneous Vagus Nerve Stimulation (tVNS), Sham Transcutaneous Vagus Nerve Stimulation (tVNS)
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 85 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Oct 1, 2026, 10:50 PM EDT
Terminated Not applicable Interventional

Task or Virtual Reality Intervention for Improving UE Function

NCT03811275
View directory record Official record
Conditions
Upper Extremity Paresis, Hemiplegia and/or Hemiparesis Following Stroke, Hemiplegic Cerebral Palsy
Interventions
Virtual Reality (A) then Task (B), Task (B) then Virtual Reality (A)
Behavioral
Lead sponsor
Idaho State University
Other
Eligibility
18 Years to 89 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Pocatello, Idaho
Source: ClinicalTrials.gov public record
Updated Apr 30, 2024 · Synced Oct 1, 2026, 10:50 PM EDT
Recruiting Not applicable Interventional

Spinal Cord Stimulation Combined With Physical Therapy in Post-Stroke Upper-Limb Motor Hemiparesis

NCT07153536
View directory record Official record
Conditions
Stroke, Spinal Cord Injuries and Disorders, Hemiparesis After Stroke
Interventions
Spinal Cord Stimulator (Medtronic Inceptiv™ System), Physical Therapy
Device · Other
Lead sponsor
Marco Capogrosso
Other
Eligibility
22 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 1, 2026, 10:50 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Trans Auricular Vagus Nerve Stimulation (taVNS) and Robotic Training for Paralyzed Arm After Stroke

NCT05339893
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
In Motion Rehabilitation Robot
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 85 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2023 · Synced Oct 1, 2026, 10:50 PM EDT
Terminated Not applicable Interventional Results available

Brain Stimulation and Rehabilitation for Adults With Chronic, Severe Arm Motor Impairment After Stroke

NCT03538795
View directory record Official record
Conditions
Stroke, Hemiplegia, Hemiparesis
Interventions
iTBS&eCIMT
Combination Product
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced Oct 1, 2026, 10:50 PM EDT
Completed Not applicable Interventional Results available

Altering Activation Patterns Post-stroke

NCT02418949
View directory record Official record
Conditions
Stroke, Muscle Spasticity, Hemiparesis
Interventions
Cyproheptadine, Placebo for Cyproheptadine, Active Movement Practice (AMP), Passive Cyclical Stretching
Drug · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 1, 2026, 10:50 PM EDT
Not yet recruiting Not applicable Interventional

Combined Aphasia and Robot-Assisted Arm Treatment for Chronic Stroke Survivors

NCT07000019
View directory record Official record
Conditions
Stroke, Aphasia Following Cerebral Infarction, Hemiparesis After Stroke
Interventions
CARAT: combined aphasia and robot-assisted arm therapy, Robot-assisted arm therapy
Behavioral
Lead sponsor
New York Medical College
Other
Eligibility
18 Years to 90 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2025 · Synced Oct 1, 2026, 10:50 PM EDT
Not listed Not applicable Interventional

EEG Brain-Machine Interface Control of an Upper-Limb Robotic Exoskeleton for Robot-Assisted Rehabilitation After Stroke

NCT05374486
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
NeuroExo co-robot neurorehabilitation system
Device
Lead sponsor
University of Houston
Other
Eligibility
20 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
3
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Oct 1, 2026, 10:50 PM EDT
Not listed Phase 3 Interventional

Safety and Effectiveness of Cortical Stimulation in the Treatment of Stroke Patients With Upper Extremity Hemiparesis

NCT00170716
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Cortical Stimulation and rehabilitation, Rehabilitation
Device · Other
Lead sponsor
Northstar Neuroscience
Industry
Eligibility
21 Years and older
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
21
States / cities
Tucson, Arizona • Los Angeles, California • San Francisco, California + 17 more
Source: ClinicalTrials.gov public record
Updated Dec 28, 2007 · Synced Oct 1, 2026, 10:50 PM EDT
Completed Not applicable Interventional

Study of the Recovery of Muscle Function in the Arm/Hand After a Stroke

NCT01422005
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Simultaneous Bimanual training, Conventional Occupational Therapy
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 75 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Oct 1, 2026, 10:50 PM EDT
Completed Phase 1 Interventional

Dose Optimization for Stroke Evaluation

NCT01749358
View directory record Official record
Conditions
Stroke, Cerebrovascular Disorders, Brain Ischemia, Infarction
Interventions
Accelerated Skill Acquisition Program (ASAP), Active Monitoring
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2017 · Synced Oct 1, 2026, 10:50 PM EDT
Completed Not applicable Interventional Results available

Robotic Brace Incorporating Electromyography for Moderate Affected Arm Impairment After Stroke

NCT01654315
View directory record Official record
Conditions
Hemiparesis
Interventions
Myomo Robotic Arm, RTP Standard Therapy
Device · Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
35 Years to 85 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 7, 2022 · Synced Oct 1, 2026, 10:50 PM EDT
Recruiting Not applicable Interventional

Efficacy of Tele-CPASS Compared to In-person CPASS Therapy for Upper Extremity Motor Recovery

NCT07661849
View directory record Official record
Conditions
Stroke, Hemiparesis, Upper Extremity Impairments, Stroke Rehabilitation
Interventions
Tele-CPASS, In-person CPASS therapy
Behavioral
Lead sponsor
University of Texas, El Paso
Other
Eligibility
21 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
3
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 1, 2026, 10:50 PM EDT
Terminated Not applicable Interventional

Transcutaneous Spinal and Peripheral Stimulation and Wrist Robotic Therapy for Patients With Spastic Stroke

NCT04113525
View directory record Official record
Conditions
Spasticity as Sequela of Stroke, Stroke, Stroke Sequelae, Hemiplegia, Spastic, Hemiparesis, Upper Limb Hypertonia, CVA
Interventions
MyoRegulator™ System
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2022 · Synced Oct 1, 2026, 10:50 PM EDT