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ClinicalTrials.gov public records Last synced May 22, 2026, 12:44 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 82 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Use of Prescription Medications Clear all
Active, not recruiting No phase listed Observational
View directory record Official record
Conditions
Opioid Use Disorder, Opioid Overdose, Death
Interventions
No intervention, observational retrospective study
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
16 Years and older
Enrollment
27,257 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced May 22, 2026, 12:44 AM EDT
Active, not recruiting Not applicable Interventional Results available
View directory record Official record
Conditions
Opioid Use Disorder (OUD)
Interventions
Communities That HEAL, Wait-list control
Other
Lead sponsor
RTI International
Other
Eligibility
Not listed
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
4
States / cities
Lexington, Kentucky • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced May 22, 2026, 12:44 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Mobile Phone App
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
1,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Indianapolis, Indiana • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced May 22, 2026, 12:44 AM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Opioid Use
Interventions
Study provides naloxone to participants who wish to have it. Not required to accept naloxone and no control.
Other
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
18 Years and older
Enrollment
600 participants
Timeline
2019 – 2023
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2019 · Synced May 22, 2026, 12:44 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Opioid-use Disorder, Overdose of Opiate, Patient Participation
Interventions
Patient Reported Outcomes Electronic Survey
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced May 22, 2026, 12:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Substance Use, Binge Drinking, Marijuana Use, Alcohol Drinking, Prescription Opioid Misuse, Illicit Drug Use
Interventions
iSTART Web-app
Behavioral
Lead sponsor
California State University, Northridge
Other
Eligibility
18 Years to 30 Years
Enrollment
1,100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Northridge, California
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced May 22, 2026, 12:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Drug Overdose, Virtual Reality
Interventions
Virtual Reality Education, Standard Education
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced May 22, 2026, 12:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Substance Use Disorders, Overdose, COVID-19
Interventions
iThrive WI Intervention
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced May 22, 2026, 12:44 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Opiate Substitution Treatment
Interventions
Standard Medical Management (SMM)
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
239 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced May 22, 2026, 12:44 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Use of Prescription Medications, Pharmacogenetic Testing
Interventions
Panel-based pharmacogenetic genotyping
Diagnostic Test
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
492 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced May 22, 2026, 12:44 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
HIV Infections
Interventions
CHECKIT!
Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
493 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced May 22, 2026, 12:44 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Opioid Use
Interventions
Informational Sheet, DisposeRx Drug Disposal kit
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
499 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 22, 2019 · Synced May 22, 2026, 12:44 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Drug Overdose
Interventions
Network overdose prevention, Standard of care health education
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced May 22, 2026, 12:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Tobacco Use, Alcohol Abuse, Prescription Drug Abuse, Substance Use
Interventions
Screening
Other
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced May 22, 2026, 12:44 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Recovery Initiation and Management after Overdose (RIMO), Passive Referral to Treatment Control
Behavioral · Other
Lead sponsor
Chestnut Health Systems
Other
Eligibility
18 Years and older
Enrollment
251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced May 22, 2026, 12:44 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Overdose, Opioid-related Disorders, Drug Addiction, Drug Abuse, Substance Abuse, Opioid Use, Unspecified, Opioid Dependence, Drug Overdose
Interventions
TTIP-PRO
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced May 22, 2026, 12:44 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Opioid Overdose, Opioid Use, Opioid Use Disorder, Opioids
Interventions
EHR-Embedded Elevated-Risk Flag, EHR-Embedded Elevated-Risk Flag with Behavioral Nudges, Usual Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
1,350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced May 22, 2026, 12:44 AM EDT
Completed Phase 1 Interventional Results available
View directory record Official record
Conditions
Opioid Use, Sedative Use
Interventions
Opioid Agonist, Sedatives
Drug
Lead sponsor
Sharon Walsh
Other
Eligibility
18 Years to 55 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced May 22, 2026, 12:44 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Substance Use Disorder (SUD)
Interventions
TAU + TRUST, TAU + TRUST + Re-entry Recovery Support, Treatment as Usual (TAU)
Behavioral · Other
Lead sponsor
Michele Staton
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
264 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
4
States / cities
Frankfort, Kentucky • Pewee Valley, Kentucky • Chillicothe, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced May 22, 2026, 12:44 AM EDT
Recruiting Phase 1Phase 2 Interventional
View directory record Official record
Conditions
Opioid Use Disorder, Opioid Overdose
Interventions
a bundled intervention, control group
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced May 22, 2026, 12:44 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Prescription Medication Understanding
Interventions
Enhanced Label
Other
Lead sponsor
Northwestern University
Other
Eligibility
30 Years and older
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 28, 2014 · Synced May 22, 2026, 12:44 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Abuses Over-The-Counter/Prescription Medications, Pain, Postoperative, Opioid Use, Physical Activity, Patient Dependence on
Interventions
Patient centered pre-op education, routine preop education
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Albuquerque, New Mexico • Rio Rancho, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced May 22, 2026, 12:44 AM EDT
Recruiting Phase 4 Interventional
View directory record Official record
Conditions
Opioid-use Disorder, Opioid Dependence, Opioid Overdose, Opioid Use, Substance Use Disorders
Interventions
Buprenorphine, Naloxone Drug Combination, Individual Counseling, Peer Recovery Support Services, Support Group, Referral to Medication Management, Assertive Outreach
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
13 Years to 17 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced May 22, 2026, 12:44 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Opioid-Related Disorders, Hepatitis C (HCV), Human Immunodeficiency Virus (HIV), Drug Overdose, Substance Abuse, Intravenous Drug Usage, Opiate Substitution Treatment, Sexually Transmitted Diseases
Interventions
Harm reduction kiosk
Behavioral
Lead sponsor
April M Young
Other
Eligibility
18 Years and older
Enrollment
752 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced May 22, 2026, 12:44 AM EDT