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ClinicalTrials.gov public records Last synced Sep 14, 2026, 10:47 AM EDT

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Showing 1–24 of 40 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Vaginal Hysterectomy Clear all
Withdrawn Not applicable Interventional

Tissue Removal During Hysterectomy: The Effect of Vaginal Versus Abdominal Morcellation on Surgical Outcomes

NCT02703246
View directory record Official record
Conditions
Fibroids
Interventions
abdominal morcellation, vaginal morcellation
Procedure
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 65 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Sep 14, 2026, 10:47 AM EDT
Completed Phase 4 Interventional Results available

Preemptive Local Anesthesia in Vaginal Surgery

NCT00318292
View directory record Official record
Conditions
Pain, Postoperative
Interventions
bupivacaine and epinephrine, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 17, 2010 · Synced Sep 14, 2026, 10:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Postoperative Pain After Vessel Sealing Device Versus Conventional Suturing Methods for Vaginal Hysterectomy and Pelvic Reconstructive Surgery

NCT05192954
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
LigaSureTM vessel sealing device
Device
Lead sponsor
Marlana McDowell
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Sep 14, 2026, 10:47 AM EDT
Recruiting Phase 4 Interventional

Vaginal Cuff Anesthesia and Post-Operative Pain Medication Use

NCT06719180
View directory record Official record
Conditions
Hysterectomy, Post Operative Analgesia
Interventions
Bupivacain, Saline (NaCl 0,9 %) (placebo)
Drug · Other
Lead sponsor
MediSys Health Network
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Flushing, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Sep 14, 2026, 10:47 AM EDT
Completed Not applicable Interventional

A Randomized Trial Comparing Horizontal and Vertical Vaginal Cuff Closure

NCT02117492
View directory record Official record
Conditions
Hysterectomy
Interventions
Cuff Closure
Procedure
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 19, 2017 · Synced Sep 14, 2026, 10:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Validated Skills Simulation With the Miya Model

NCT05418764
View directory record Official record
Conditions
Vaginal Hysterectomy
Interventions
Miyamodel Training
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 14, 2026, 10:47 AM EDT
Completed Not applicable Interventional

A Novel Tapered Applicator for Vaginal Vault Brachytherapy

NCT04318340
View directory record Official record
Conditions
Endometrial Cancer, Brachytherapy, Quality of Life
Interventions
Tapered applicator, Standard applicator
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Sep 14, 2026, 10:47 AM EDT
Completed Not applicable Interventional

The Effect of Vertical Versus Horizontal Vaginal Cuff Closure on Vaginal Length After Laparoscopic Hysterectomy

NCT02276261
View directory record Official record
Conditions
Hysterectomy
Interventions
Vaginal cuff closure - vertical, Vaginal cuff closure - horizontal
Procedure
Lead sponsor
Bridgeport Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Bridgeport, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 19, 2016 · Synced Sep 14, 2026, 10:47 AM EDT
Not listed Not applicable Interventional

Vaginal Cuff Closure Time Using Unidirectional Barbed Suture in Robotic Hysterectomy

NCT01814579
View directory record Official record
Conditions
Disease (or Disorder); Gynecological
Interventions
Unidirectional Barbed Suture (V-Loc), polyglactin 910 (Vicryl)
Device
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 25, 2013 · Synced Sep 14, 2026, 10:47 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Vaginal Natural Orifice Transluminal Endoscopic (vNOTE) Hysterectomy With Uterosacral Suspension

NCT07413861
View directory record Official record
Conditions
Prolapse Pelvic, Hysterectomy
Interventions
Uterosacral suspension, Hysterectomy by vNOTES approach
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 14, 2026, 10:47 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Oxidized Regenerated Cellulose to Decrease Vaginal Cuff Complications

NCT01584128
View directory record Official record
Conditions
Vaginal Cuff Complications
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
20 Years to 80 Years · Female only
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Sep 14, 2026, 10:47 AM EDT
Not listed Phase 4 Interventional

PROJECT PREVENT: Metronidazole Antibiotic Per Vagina Before Hysterectomy: Is Additional Antibiotic Prophylaxis Beneficial?

NCT04478617
View directory record Official record
Conditions
Post-Op Infection
Interventions
Metronidazole Vaginal
Drug
Lead sponsor
New York Medical College
Other
Eligibility
18 Years and older · Female only
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
New York, New York • Valhalla, New York
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Sep 14, 2026, 10:47 AM EDT
Completed Phase 3 Interventional

Laparoscopic Surgery or Standard Surgery in Treating Patients With Endometrial Cancer or Cancer of the Uterus

NCT00002706
View directory record Official record
Conditions
Endometrial Adenocarcinoma, Stage I Uterine Corpus Cancer, Stage I Uterine Sarcoma, Stage II Uterine Corpus Cancer, Stage II Uterine Sarcoma
Interventions
Laparoscopic Surgery, Quality-of-Life Assessment, Therapeutic Conventional Surgery
Procedure · Other
Lead sponsor
Gynecologic Oncology Group
Network
Eligibility
18 Years and older · Female only
Enrollment
2,616 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1996
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2015 · Synced Sep 14, 2026, 10:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prophylactic Modified McCall Culdoplasty During Total Laparoscopic Hysterectomy

NCT01840176
View directory record Official record
Conditions
Vaginal Vault Prolapse, Sexual Function
Interventions
McCall culdoplasty
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 14, 2026, 10:47 AM EDT
Not listed Not applicable Interventional

Prophylactic Uterosacral Ligament Suspension at the Time of Hysterectomy for Prevention of Vaginal Vault Prolapse

NCT01364025
View directory record Official record
Conditions
Prolapse of Vaginal Vault After Hysterectomy
Interventions
uterosacral ligament suspension colpopexy bilateral
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
21 Years to 99 Years · Female only
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Sep 14, 2026, 10:47 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparison of the Effects of Cervical Vasopressin Versus no Premedication on Blood Loss During Vaginal Hysterectomy: A Randomized, Placebo Controlled Trial

NCT00799292
View directory record Official record
Conditions
Blood Loss During Vaginal Hysterectomy
Interventions
Vasopressin
Drug
Lead sponsor
Ascher-Walsh, Charles, M.D.
Individual
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2018 · Synced Sep 14, 2026, 10:47 AM EDT
Terminated Phase 4 Interventional Results available

Vaginal Preparation Prior to Hysterectomy

NCT03412734
View directory record Official record
Conditions
Hysterectomy
Interventions
Chlorhexidine, Iodine
Drug
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 10, 2021 · Synced Sep 14, 2026, 10:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Does 3D Laparoscopy Improve Vaginal Cuff Suture Time?

NCT02192606
View directory record Official record
Conditions
Uterine Fibroids, Abnormal Uterine Bleeding, Pelvic Pain, Adenomyosis
Interventions
Storz 3D Laparoscopy System, 2D Laparoscopy
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 23, 2018 · Synced Sep 14, 2026, 10:47 AM EDT
Completed No phase listed Observational

Evaluation of the Relationship Between Vaginal and Lower Urinary Tract Microbiomes and Infection After Hysterectomy

NCT02751073
View directory record Official record
Conditions
Pelvic Organ Prolapse, Hysterectomy, Urinary Tract Infection
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Sep 14, 2026, 10:47 AM EDT
Completed Phase 4 Interventional Results available

Barbed Suture vs Smooth Suture for Vaginal Cuff Closure

NCT01262573
View directory record Official record
Conditions
Closure of Vaginal Cuff at Laparoscopic Hysterectomy
Interventions
Closure of vaginal cuff
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 15, 2017 · Synced Sep 14, 2026, 10:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Postoperative Bleeding After Hysterectomy Via Independent Closure of Vaginal Cuff Angles

NCT05174988
View directory record Official record
Conditions
Postoperative Bleeding, Patient Satisfaction, Complications, Operative Time
Interventions
Angle stitch
Procedure
Lead sponsor
Texas Tech University Health Sciences Center, El Paso
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Sep 14, 2026, 10:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Outcomes on Abdominal Versus Vaginal Morcellation At Time of Hysterectomy

NCT04434066
View directory record Official record
Conditions
Abnormal Uterine Bleeding, Uterine Bleeding, Fibroid Uterus, Surgery
Interventions
Total Laparoscopic Hysterectomy
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Sep 14, 2026, 10:47 AM EDT
Completed No phase listed Observational Results available

Clinical Utility of Postoperative Hemoglobin Testing

NCT04170764
View directory record Official record
Conditions
Anaemia Postoperative
Interventions
Not listed
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
664 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Sep 14, 2026, 10:47 AM EDT
Completed No phase listed Observational

Histological Characterization of Vaginal Cuff Tissue Using Different Energy Sources During Robotic Hysterectomy

NCT01846858
View directory record Official record
Conditions
Extent of Thermal Injury Using Different Energy Sources at the Time of Robotic Hysterectomy Procedure
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 18, 2014 · Synced Sep 14, 2026, 10:47 AM EDT