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Showing 1–24 of 40 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Vaginal Hysterectomy Clear all
Completed No phase listed Observational Accepts healthy volunteers

Oxidized Regenerated Cellulose to Decrease Vaginal Cuff Complications

NCT01584128
View directory record Official record
Conditions
Vaginal Cuff Complications
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
20 Years to 80 Years · Female only
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Jul 21, 2026, 11:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Outcomes on Abdominal Versus Vaginal Morcellation At Time of Hysterectomy

NCT04434066
View directory record Official record
Conditions
Abnormal Uterine Bleeding, Uterine Bleeding, Fibroid Uterus, Surgery
Interventions
Total Laparoscopic Hysterectomy
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Jul 21, 2026, 11:15 AM EDT
Completed No phase listed Observational

Permanent Versus Delayed-Absorbable Monofilament Suture

NCT04506177
View directory record Official record
Conditions
Hysterectomy, Sacrocolpopexy
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
5
States / cities
Augusta, Georgia • Chicago, Illinois • Chapel Hill, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2024 · Synced Jul 21, 2026, 11:15 AM EDT
Completed Phase 4 Interventional Results available

Barbed Suture vs Smooth Suture for Vaginal Cuff Closure

NCT01262573
View directory record Official record
Conditions
Closure of Vaginal Cuff at Laparoscopic Hysterectomy
Interventions
Closure of vaginal cuff
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 15, 2017 · Synced Jul 21, 2026, 11:15 AM EDT
Completed Not applicable Interventional

The Effect of Vertical Versus Horizontal Vaginal Cuff Closure on Vaginal Length After Laparoscopic Hysterectomy

NCT02276261
View directory record Official record
Conditions
Hysterectomy
Interventions
Vaginal cuff closure - vertical, Vaginal cuff closure - horizontal
Procedure
Lead sponsor
Bridgeport Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Bridgeport, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 19, 2016 · Synced Jul 21, 2026, 11:15 AM EDT
Not listed Not applicable Interventional

Prophylactic Uterosacral Ligament Suspension at the Time of Hysterectomy for Prevention of Vaginal Vault Prolapse

NCT01364025
View directory record Official record
Conditions
Prolapse of Vaginal Vault After Hysterectomy
Interventions
uterosacral ligament suspension colpopexy bilateral
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
21 Years to 99 Years · Female only
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Jul 21, 2026, 11:15 AM EDT
Completed Not applicable Interventional

A Novel Tapered Applicator for Vaginal Vault Brachytherapy

NCT04318340
View directory record Official record
Conditions
Endometrial Cancer, Brachytherapy, Quality of Life
Interventions
Tapered applicator, Standard applicator
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Jul 21, 2026, 11:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study Investigating Role of Unalike Patient Positioning on PROMIS Scores

NCT03446950
View directory record Official record
Conditions
Physical Activity, Surgery, Vaginal Hysterectomy, Vaginal Surgery
Interventions
Vaginal Surgery
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older · Female only
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 8, 2020 · Synced Jul 21, 2026, 11:15 AM EDT
Completed Not applicable Interventional

Vaginal Cuff Closure in Robotic Hysterectomy

NCT02696239
View directory record Official record
Conditions
Complications of Medical Care
Interventions
V-lock suture, Vicryl Suture, Lapra-Ty II
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Jul 21, 2026, 11:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Difference in Pain, Quality of Life Following Vaginal Hysterectomy With Vaginal Reconstruction Versus Robotic Colpopexy?

NCT02049996
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 8, 2016 · Synced Jul 21, 2026, 11:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Postoperative Pain After Vessel Sealing Device Versus Conventional Suturing Methods for Vaginal Hysterectomy and Pelvic Reconstructive Surgery

NCT05192954
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
LigaSureTM vessel sealing device
Device
Lead sponsor
Marlana McDowell
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Jul 21, 2026, 11:15 AM EDT
Recruiting Phase 4 Interventional

Vaginal Cuff Anesthesia and Post-Operative Pain Medication Use

NCT06719180
View directory record Official record
Conditions
Hysterectomy, Post Operative Analgesia
Interventions
Bupivacain, Saline (NaCl 0,9 %) (placebo)
Drug · Other
Lead sponsor
MediSys Health Network
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Flushing, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Jul 21, 2026, 11:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prophylactic Modified McCall Culdoplasty During Total Laparoscopic Hysterectomy

NCT01840176
View directory record Official record
Conditions
Vaginal Vault Prolapse, Sexual Function
Interventions
McCall culdoplasty
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Jul 21, 2026, 11:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

VITOM Study: A Randomized, Controlled Trial.

NCT03120689
View directory record Official record
Conditions
Pelvic Organ Prolapse, Prolapse of Vaginal Vault After Hysterectomy, Bulging of Vaginal Wall, Incontinence, Fistula
Interventions
Live Surgery using VITOM, Live Surgery without VITOM, Video viewing with VITOM, Video viewing with standard handheld high-definition camera
Other
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Jul 21, 2026, 11:15 AM EDT
Withdrawn Not applicable Interventional

Tissue Removal During Hysterectomy: The Effect of Vaginal Versus Abdominal Morcellation on Surgical Outcomes

NCT02703246
View directory record Official record
Conditions
Fibroids
Interventions
abdominal morcellation, vaginal morcellation
Procedure
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 65 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Jul 21, 2026, 11:15 AM EDT
Terminated Not applicable Interventional

Pelvic Floor Support After Laparoscopic Hysterectomy for Benign Conditions: A Randomized Controlled Trial Comparing Vaginal Cuff Closure Techniques

NCT03753516
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Laparoscopic - Vaginal Cuff Closure, Vaginal- Vaginal Cuff Closure
Procedure
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced Jul 21, 2026, 11:15 AM EDT
Completed No phase listed Observational

Evaluation of the Relationship Between Vaginal and Lower Urinary Tract Microbiomes and Infection After Hysterectomy

NCT02751073
View directory record Official record
Conditions
Pelvic Organ Prolapse, Hysterectomy, Urinary Tract Infection
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Jul 21, 2026, 11:15 AM EDT
Not listed Not applicable Interventional

Vaginal Cuff Closure Time Using Unidirectional Barbed Suture in Robotic Hysterectomy

NCT01814579
View directory record Official record
Conditions
Disease (or Disorder); Gynecological
Interventions
Unidirectional Barbed Suture (V-Loc), polyglactin 910 (Vicryl)
Device
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 25, 2013 · Synced Jul 21, 2026, 11:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Postoperative Bleeding After Hysterectomy Via Independent Closure of Vaginal Cuff Angles

NCT05174988
View directory record Official record
Conditions
Postoperative Bleeding, Patient Satisfaction, Complications, Operative Time
Interventions
Angle stitch
Procedure
Lead sponsor
Texas Tech University Health Sciences Center, El Paso
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Jul 21, 2026, 11:15 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparison of the Effects of Cervical Vasopressin Versus no Premedication on Blood Loss During Vaginal Hysterectomy: A Randomized, Placebo Controlled Trial

NCT00799292
View directory record Official record
Conditions
Blood Loss During Vaginal Hysterectomy
Interventions
Vasopressin
Drug
Lead sponsor
Ascher-Walsh, Charles, M.D.
Individual
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2018 · Synced Jul 21, 2026, 11:15 AM EDT
Terminated Not applicable Interventional

Comparison of Laparoscopic to Vaginal Surgical Repair for Uterine Prolapse

NCT01594372
View directory record Official record
Conditions
Uterine Prolapse
Interventions
Laparoscopic supracervical hysterectomy with sacropexy, Vaginal hysterectomy with uterosacral colposuspension
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Jul 21, 2026, 11:15 AM EDT
Terminated Phase 4 Interventional Results available

Liposomal Bupivacaine in Vaginal Hysterectomy

NCT03907033
View directory record Official record
Conditions
Vaginal Hysterectomy
Interventions
Liposomal bupivacaine, Bupivacaine Hydrochloride
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 14, 2021 · Synced Jul 21, 2026, 11:15 AM EDT
Completed Phase 4 Interventional Results available

Preemptive Local Anesthesia in Vaginal Surgery

NCT00318292
View directory record Official record
Conditions
Pain, Postoperative
Interventions
bupivacaine and epinephrine, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 17, 2010 · Synced Jul 21, 2026, 11:15 AM EDT
Completed No phase listed Observational Results available

Clinical Utility of Postoperative Hemoglobin Testing

NCT04170764
View directory record Official record
Conditions
Anaemia Postoperative
Interventions
Not listed
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
664 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Jul 21, 2026, 11:15 AM EDT