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ClinicalTrials.gov public records Last synced May 22, 2026, 3:37 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Ventilatory Depression Clear all
Completed No phase listed Observational
View directory record Official record
Conditions
Opioid Induced Respiratory Depression
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Day and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 22, 2013 · Synced May 22, 2026, 3:37 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Asthma, Lung Function Decreased, Food Allergy, Allergic Sensitisation, Allergic Rhinitis, COPD, Atopy
Interventions
Dietary intake of various nutrients, foods and biocompounds
Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
15 Years to 75 Years
Enrollment
3,500 participants
Timeline
2007 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced May 22, 2026, 3:37 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Delirium, Respiratory Depression, Overmedication
Interventions
Verum Acupuncture, Sham Acupuncture
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 19, 2020 · Synced May 22, 2026, 3:37 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Opiate Induced Respiratory Depression
Interventions
CX1739 - 300 mg, CX1739 - 600 mg, CX1739 - 900 mg, Placebo
Drug
Lead sponsor
RespireRx
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2016 · Synced May 22, 2026, 3:37 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Pain, Ventilatory Depression
Interventions
hydromorphone
Drug
Lead sponsor
Northwestern University
Other
Eligibility
21 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 21, 2015 · Synced May 22, 2026, 3:37 AM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Cystic Fibrosis in Children
Interventions
Jamboxx Respiratory Therapy Device, Autogenic Draining Training
Device · Other
Lead sponsor
My Music Machines Inc.
Industry
Eligibility
5 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Sep 1, 2020 · Synced May 22, 2026, 3:37 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Ventilatory Depression, Postoperative Respiratory Failure
Interventions
Oxygen Gas for Inhalation
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced May 22, 2026, 3:37 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Drug Overdose, Opioid-Related Disorders
Interventions
Diagnostic algorithms that detects/predicts hypoventilation
Device
Lead sponsor
RTM Vital Signs, LLC
Industry
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2019 · Synced May 22, 2026, 3:37 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Sedation
Interventions
Dexmedetomidine load, Ketamine load, Midazolam load, Fentanyl load, Dexmedetomidine maintenance, Ketamine maintenance, Midazolam demand, Fentanyl demand, Benadryl demand
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 25, 2019 · Synced May 22, 2026, 3:37 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Opioid Overdose
Interventions
Nalmefene HCl injection, Naloxone HCl intranasal
Drug
Lead sponsor
Purdue Pharma LP
Industry
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced May 22, 2026, 3:37 AM EDT
Enrolling by invitation Not applicable Interventional
View directory record Official record
Conditions
Respiration Disorders
Interventions
Study to evaluate a Respiratory Monitoring System (RMS) with a Tracheal Sound Sensor (TSS) for detecting and predicting opioid induced respiratory Depression (OIRD).
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced May 22, 2026, 3:37 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Breathing, Mouth, Lung Function Decreased
Interventions
Impulse Oscillometer
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
20 participants
Timeline
2021 – 2023
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced May 22, 2026, 3:37 AM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Opioids, Obstructive Sleep Apnea (OSA)
Interventions
Morphine p.o., Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced May 22, 2026, 3:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Blood Pressure, HDL Low, Stress, Lung Function Decreased, Quality of Life, Energy Supply; Deficiency, Concentration Ability Impaired, Joint Instability, Immune Deficiency
Interventions
Stem Cell 100+
Dietary Supplement
Lead sponsor
Centagen, Inc.
Industry
Eligibility
35 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2017 · Synced May 22, 2026, 3:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Postoperative Complications
Interventions
Alaris ETCO2 monitor - cont. resp. rate, & apnea events
Device
Lead sponsor
Texas Health Resources
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2008 · Synced May 22, 2026, 3:37 AM EDT
Completed Phase 1Phase 2 Interventional
View directory record Official record
Conditions
Respiratory Depression, Elective Surgery
Interventions
Verbal prompt, Skin Stimulus
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 17, 2019 · Synced May 22, 2026, 3:37 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary), Respiratory Complications Due to Anesthesia
Interventions
Infrared Pupillometry
Device
Lead sponsor
NeurOptics Inc
Industry
Eligibility
3 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
San Francisco, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced May 22, 2026, 3:37 AM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Breathing, Mouth, Lung Function Decreased, Dyspnea, Shortness of Breath
Interventions
Oscillometer
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
50 participants
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 7, 2025 · Synced May 22, 2026, 3:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Respiratory Depression, Blood Pressure
Interventions
ozone
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years to 55 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2013 · Synced May 22, 2026, 3:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Respiratory Depression
Interventions
Capnostream
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 3, 2017 · Synced May 22, 2026, 3:37 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Hypercapnia, Ventilatory Depression
Interventions
Oxycodone and Midazolam, Oxycodone, Paroxetine, and Quetiapine
Drug
Lead sponsor
Food and Drug Administration (FDA)
Federal
Eligibility
18 Years to 50 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
West Bend, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced May 22, 2026, 3:37 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Anesthesia
Interventions
NM3, Phillips Medical, Wallingford CT: verbal prompts to breathe with an optional shoulder shake
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced May 22, 2026, 3:37 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Breathing, Mouth, Lung Function Decreased, Vocal Cord Dysfunction, Laryngeal Obstruction, Asthma
Interventions
Impulse Oscillometer
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
43 participants
Timeline
2022 – 2024
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced May 22, 2026, 3:37 AM EDT
Completed Phase 4 Interventional
View directory record Official record
Conditions
Acute Pain, Burns, Adverse Drug Event, Respiratory Depression, Nausea and Vomiting, Postoperative
Interventions
Oliceridine, Historical opioid use
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced May 22, 2026, 3:37 AM EDT