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Showing 1–24 of 33 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Ventral Incisional Hernia Clear all
Recruiting Not applicable Interventional

Prophylactic Reinforcement of Ventral Abdominal Incisions Trial

NCT03911700
View directory record Official record
Conditions
Open Midline Laparotomy
Interventions
Phasix™ Mesh
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
477 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2031
U.S. locations
31
States / cities
Phoenix, Arizona • Los Angeles, California • San Francisco, California + 25 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Jul 22, 2026, 5:04 AM EDT
Terminated No phase listed Observational

Prevena Incision Management System Wound Care

NCT02953769
View directory record Official record
Conditions
Ventral Hernia
Interventions
Not listed
Lead sponsor
AdventHealth
Other
Eligibility
18 Years to 89 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Celebration, Florida
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Jul 22, 2026, 5:04 AM EDT
Completed No phase listed Observational

Flexible Composite Next Generation Tissue Separating Mesh in Laparoscopic Incisional/Ventral Hernia Repair

NCT01162564
View directory record Official record
Conditions
Incisional Hernia, Ventral Hernia
Interventions
NG-TSM
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
6
States / cities
Jefferson City, Missouri • St Louis, Missouri • The Bronx, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2011 · Synced Jul 22, 2026, 5:04 AM EDT
Recruiting Phase 4 Interventional

Preoperative BOTOX® Injection for Large Ventral Hernia Repair

NCT07220382
View directory record Official record
Conditions
Hernia Abdominal Wall, Botox Injection, Hernia Incisional Ventral, Hernia Repair With Compartment Syndrome, Hernia Surgery, Hernia, Hernia Incisional
Interventions
OnabotulinumtoxinA Injection, Saline (placebo) Injection, OnabotulinumtoxinA, 0.9 % Normal Saline, Open Ventral Hernia Repair
Procedure · Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Terminated No phase listed Observational

Veritas in Non-Bridging Ventral Hernia Repair

NCT01426477
View directory record Official record
Conditions
Hernia
Interventions
Not listed
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
4
States / cities
Jacksonville, Florida • Lakeland, Florida • Atlanta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Jul 22, 2026, 5:04 AM EDT
Terminated Not applicable Interventional

Gentrix™ Versus Biological or Prosthetic Mesh

NCT03034213
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Gentrix™ Surgical Matrix (Treatment), Permacol, Parietex, Progrip, Strattice Perforated, or Surgimend (Control)
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
3
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Jul 22, 2026, 5:04 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Cytokine Response to Abdominal Wall Reconstruction

NCT07422584
View directory record Official record
Conditions
Incisional Ventral Hernia
Interventions
Not applicable- observational study
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Jul 22, 2026, 5:04 AM EDT
Terminated No phase listed Observational

Observational Biologic or Prosthetic Mesh

NCT03317665
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Mesh for hernia repair
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
3
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Jul 22, 2026, 5:04 AM EDT
Recruiting Not applicable Interventional

GORE® ENFORM Biomaterial Product Study

NCT04718168
View directory record Official record
Conditions
Hernia, Ventral, Hernia, Hiatal, Hernia, Diaphragmatic, Incisional Hernia
Interventions
Gore ENFORM Biomaterial (Preperitoneal), Gore ENFORM Biomaterial (Intraperitoneal)
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
245 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
9
States / cities
San Diego, California • Denver, Colorado • Sarasota, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional

Randomized Control Trial Comparing Transfascial Suture for Mesh Fixation to No Mesh Fixation

NCT03938688
View directory record Official record
Conditions
Ventral Hernia, Incisional Hernia
Interventions
Mesh placement with Transfascial Sutures
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
325 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Jul 22, 2026, 5:04 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Shear-Wave Elastography

NCT06306976
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Elective Midline Laparotomy, Imaging: Ultrasound, Tensiometry
Procedure · Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Does a Transabdominal Plane Block Decrease Patient Pain After Ventral Hernia Repair?

NCT02007096
View directory record Official record
Conditions
Ventral Hernia, Umbilical Hernia, Incisional Hernia, Postoperative Complications, Pain, Postoperative
Interventions
Transabdominal Plane Block, Non Transabdominal Plane Block
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 18, 2018 · Synced Jul 22, 2026, 5:04 AM EDT
Not yet recruiting Not applicable Interventional

The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery

NCT07145099
View directory record Official record
Conditions
Ventral Hernia, Ventral Incisional Hernia, Post Operative Pain
Interventions
PT Group, Usual Care
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional Results available

Repair of Infected or Contaminated Hernias

NCT00617357
View directory record Official record
Conditions
Hernia
Interventions
LTM (Strattice Reconstructive Tissue Matrix)
Device
Lead sponsor
LifeCell
Industry
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
15
States / cities
La Jolla, California • New Haven, Connecticut • New Orleans, Louisiana + 10 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2015 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional Results available

A Prospective Trial of a Bio-absorbable Mesh in Challenging Laparoscopic Ventral or Incisional Hernia Repair

NCT02712398
View directory record Official record
Conditions
Hernia, Ventral, Incisional Hernia
Interventions
Phasix™ ST
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
16
States / cities
New Haven, Connecticut • Celebration, Florida • Atlanta, Georgia + 13 more
Source: ClinicalTrials.gov public record
Updated Jan 7, 2021 · Synced Jul 22, 2026, 5:04 AM EDT
Active, not recruiting No phase listed Observational

Assessment of GORE® SYNECOR Biomaterial in Focused Patient Populations and Long-Term Application

NCT05094089
View directory record Official record
Conditions
Hernia, Ventral, Hernia Incisional, Hernia Incisional Ventral
Interventions
Hernia repair with mesh
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years to 80 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
8
States / cities
Atlanta, Georgia • Boston, Massachusetts • Grand Rapids, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional

Watchful Waiting of Incisional Hernias

NCT00351455
View directory record Official record
Conditions
Incisional Hernia, Ventral Hernia, Umbilical Hernia
Interventions
smoking cessation, tighter diabetic control, diet and exercise program
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Jul 22, 2026, 5:04 AM EDT
Terminated Not applicable Interventional Results available

Complex Ventral Hernia Repair Using Biologic or Synthetic Mesh

NCT02041494
View directory record Official record
Conditions
Hernia, Ventral
Interventions
Ventralight, Strattice
Device
Lead sponsor
Hobart Harris
Other
Eligibility
21 Years and older
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional

Cosmetic Outcomes of Umbilical Hernia Incisions

NCT06738121
View directory record Official record
Conditions
Umbilical Hernia
Interventions
Infra-umbilical incision, Transumbilical incision
Procedure
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
Up to 9 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Open Complex Ventral Incisional Hernia Repair Using Biosynthetic Material for Midline Fascial Closure Reinforcement

NCT01325792
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
GORE® BIO-A® Tissue Reinforcement
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
8
States / cities
San Diego, California • Indianapolis, Indiana • St Louis, Missouri + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 23, 2015 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Surgisis Gold Graft for Incision Reinforcement After Open Bariatric Surgery

NCT00274625
View directory record Official record
Conditions
Hernia, Obesity
Interventions
Surgisis Gold Graft, Control
Device · Procedure
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
18 Years and older
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
2
States / cities
Rochester, Minnesota • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 11, 2014 · Synced Jul 22, 2026, 5:04 AM EDT
Completed No phase listed Observational Results available

A Prospective, Observational Study Utilizing Phasix™ Mesh During Ventral and Incisional Hernia Repair Surgery

NCT01863030
View directory record Official record
Conditions
Ventral Hernia
Interventions
Phasix mesh implant
Device
Lead sponsor
John Roth
Other
Eligibility
18 Years to 100 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 20, 2020 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional Results available

Xen Matrix™ AB Surgical Graft in Ventral or Incisional Midline Hernias

NCT02691962
View directory record Official record
Conditions
Incisional Hernia
Interventions
Xen Matrix AB
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
11
States / cities
Los Angeles, California • San Francisco, California • Atlanta, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2021 · Synced Jul 22, 2026, 5:04 AM EDT
Completed No phase listed Observational

Observational Study to Evaluate Ventral Incisional Hernia Repair Using a Biologic Mesh (Cook Biodesign)

NCT02129140
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Hernia graft/mesh
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 4, 2020 · Synced Jul 22, 2026, 5:04 AM EDT