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Showing 1–16 of 16 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Vertebral Metastases Clear all
Terminated Not applicable Interventional Results available

Vertebral Augmentation and Radiotherapy of Collapse Spinal Metastatic Cancer

NCT02376933
View directory record Official record
Conditions
Metastatic Cancers, Multiple Myeloma, Vertebral Fracture
Interventions
Vertebroplasty, Radiotherapy
Procedure · Radiation
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 6, 2018 · Synced Jul 21, 2026, 11:11 AM EDT
Terminated Not applicable Interventional Results available

Conformal High Dose Intensity Modulated Radiation Therapy for Disease to Thoracic and Lumbar Spine

NCT01654068
View directory record Official record
Conditions
Vertebral Metastasis
Interventions
Conformal High Dose Intensity Modulated Radiation Therapy
Radiation
Lead sponsor
Ronald McGarry
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Jul 21, 2026, 11:11 AM EDT
Completed Not applicable Interventional Results available

Stereotactic Body Radiotherapy for Spine Tumors

NCT01347307
View directory record Official record
Conditions
Spinal Metastases, Vertebral Metastases, Benign Spinal Tumors, Chordoma, Meningioma, Schwannoma, Neurofibroma, Paragangliomas, Arteriovenous Malformations
Interventions
SBRT for Benign Extradural Spine Tumors, SBRT for Vertebral/Paraspinal Metastases
Radiation
Lead sponsor
Mercy Research
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced Jul 21, 2026, 11:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessment of Vertebral Fracture Risk for First Time Liver Transplant Candidates

NCT03811873
View directory record Official record
Conditions
Metabolic Bone Disease, Transplant-Related Disorder, Secondary Osteoporosis
Interventions
Dual x-ray absorptiometry, Vertebral Fracture Assessment
Diagnostic Test · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Jul 21, 2026, 11:11 AM EDT
Active, not recruiting Not applicable Interventional

Radiation Therapy Alone Versus Radiation Therapy Plus Radiofrequency Ablation (RFA)/Vertebral Augmentation

NCT04375891
View directory record Official record
Conditions
Oncology, Spine Metastases
Interventions
Radiation Therapy, Radiofrequency Ablation (RFA)
Radiation
Lead sponsor
Baptist Health South Florida
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Jul 21, 2026, 11:11 AM EDT
Completed No phase listed Observational

Direct Injection of Alcohol for the Treatment of Spinal Tumors

NCT00001417
View directory record Official record
Conditions
Hemangioma, Neoplasm Metastasis, Spinal Neoplasm
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 21, 2026, 11:11 AM EDT
Completed No phase listed Observational

A Pilot Study to Explore Serum and Imaging Biomarkers in Patients With Spinal Cord Compression

NCT00928382
View directory record Official record
Conditions
Cancer, Spine Metastasis
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 21, 2026, 11:11 AM EDT
Terminated Phase 4 Interventional Results available

Anderson Circulating Tumor Cell Burden (CTCB) Study

NCT00819832
View directory record Official record
Conditions
Cancer, Spinal Disease, Vertebral Compression Fractures
Interventions
Kyphoplasty, Vertebroplasty, Cavity SpineWand
Procedure · Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Jul 21, 2026, 11:11 AM EDT
Active, not recruiting Phase 2 Interventional

Cement Augmentation in Preventing Vertebral Body Compression Fracture Following Spine Stereotactic Radiosurgery in Patients With Solid Tumors and Spinal Metastases

NCT02387905
View directory record Official record
Conditions
Metastatic Malignant Neoplasm in the Spine, Metastatic Malignant Solid Neoplasm
Interventions
Management of Therapy Complications, Quality-of-Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery
Procedure · Other · Radiation
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jul 21, 2026, 11:11 AM EDT
Completed No phase listed Observational

The Epidemiology, Process and Outcomes of Spine Oncology (EPOSO)

NCT01825161
View directory record Official record
Conditions
Secondary Malignant Neoplasm of Vertebral Column
Interventions
Not listed
Lead sponsor
AO Foundation, AO Spine
Other
Eligibility
18 Years to 75 Years
Enrollment
454 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
5
States / cities
Kansas City, Kansas • Baltimore, Maryland • Rochester, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2022 · Synced Jul 21, 2026, 11:11 AM EDT
Terminated Not applicable Interventional Results available

Phase II Trial of Stereotactic Radiation Therapy (SRT) Versus SRT Plus Vertebral Augmentation Procedure (VAP) for Vertebral Metastasis

NCT01527292
View directory record Official record
Conditions
Vertebral Metastasis
Interventions
Stereotactic Radiation Therapy, SRT with Vertebral Augmentation Procedure
Radiation
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Jul 21, 2026, 11:11 AM EDT
Completed Phase 1Phase 2 Interventional

Effect of Samarium on the Relief of Pain Due to Vertebral Metastases

NCT00374751
View directory record Official record
Conditions
Cancer, Metastasis, Pain
Interventions
Samarium (153SM)
Drug
Lead sponsor
New York Presbyterian Brooklyn Methodist Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2016
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2019 · Synced Jul 21, 2026, 11:11 AM EDT
Completed No phase listed Observational

The STAR Prospective Clinical Series

NCT02217150
View directory record Official record
Conditions
Metastasis to Vertebral Column
Interventions
Not listed
Lead sponsor
DFINE Inc.
Industry
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
8
States / cities
Escondido, California • Los Angeles, California • Kansas City, Kansas + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced Jul 21, 2026, 11:11 AM EDT
Recruiting Phase 2 Interventional

Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

NCT04218617
View directory record Official record
Conditions
Spine Metastases, Spine Stereotactic Radiosurgery (sSRS)
Interventions
Diagnostic MRI, Planning MRI, Simulation CT, QOL assessment, Brief pain inventory (BPI), sSRS in 1 fraction, sSRS in 2 fraction
Device · Other · Radiation
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jul 21, 2026, 11:11 AM EDT
Completed Phase 4 Interventional

FREE Study - Fracture Reduction Evaluation

NCT00211211
View directory record Official record
Conditions
Osteopenia, Osteoporosis, Multiple Myeloma, Bone Neoplasms
Interventions
Balloon Kyphoplasty
Device
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Jul 21, 2026, 11:11 AM EDT
Completed Not applicable Interventional

Quantitative MRI for Functional Assessment Following SBRT for Spinal Metastases

NCT04248543
View directory record Official record
Conditions
Spinal Metastases
Interventions
qMRI with Gadoteridol contrast agent
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Jul 21, 2026, 11:11 AM EDT