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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Weight Loss Trial Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Behavioral Lifestyle Intervention for Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) in Adults

NCT06121999
View directory record Official record
Conditions
Metabolic Associated-dysfunction Steatotic Liver Disease (MASLD), Metabolic Associated-dysfunction Steatohepatitis (MASH)
Interventions
Standard of care acceptance-based behavioral weight loss program, Occupational therapy dietary and lifestyle modifications
Behavioral
Lead sponsor
Grand Valley State University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Wyoming, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Jul 23, 2026, 2:07 AM EDT
Not yet recruiting Not applicable Interventional

Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans

NCT07560969
View directory record Official record
Conditions
Diabetes, Physical Activity, Food Security, Nutrition Security
Interventions
Culturally-tailored, enhanced adaption of Diabetes Prevention Program
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Not applicable Interventional

A Mail and Video-based Weight Loss Trial in Breast Cancer Survivors

NCT02681965
View directory record Official record
Conditions
Breast Cancer Survivorship, Obesity
Interventions
LEAN book/videos
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 79 Years · Female only
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 28, 2018 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of a Novel Nutraceutical on Weight Loss and Weight Maintenance in Obese Subjects

NCT01656681
View directory record Official record
Conditions
Obesity
Interventions
THIAA, Placebo
Dietary Supplement
Lead sponsor
MetaProteomics LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Gig Harbor, Washington
Source: ClinicalTrials.gov public record
Updated May 17, 2018 · Synced Jul 23, 2026, 2:07 AM EDT
Terminated No phase listed Observational

Identify microRNAs in Cachexia in Pancreatic Carcinoma

NCT05275075
View directory record Official record
Conditions
Resectable Pancreatic Adenocarcinoma
Interventions
Pancreatic cancer microRNA and messenger RNA expression.
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The EMBER Trial for Weight Management Engagement

NCT05424081
View directory record Official record
Conditions
Obesity
Interventions
EMBER, Control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 79 Years
Enrollment
470 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Palo Alto, California • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Internet Assisted Obesity Treatment

NCT00265954
View directory record Official record
Conditions
Overweight, Obesity
Interventions
internet, in-person and internet+in-person
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
481 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
2
States / cities
Little Rock, Arkansas • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Not applicable Interventional Results available

A Trial to Test an Acceptance-based Therapy Program Among Adolescent Girls With Overweight/Obesity

NCT04484831
View directory record Official record
Conditions
Weight Loss, Obesity, Overweight
Interventions
ABT Weight Loss Intervention, Enhanced Care
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
14 Years to 19 Years · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Not applicable Interventional Results available

Gaining Optimism After Weight Loss Surgery (GOALS) I

NCT04867902
View directory record Official record
Conditions
Bariatric Surgery
Interventions
Positive Psychology-Motivational Interviewing Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Breast Cancer Recurrence With Weight Loss

NCT01112839
View directory record Official record
Conditions
Breast Cancer, Overweight, Obesity
Interventions
Less Intensive, Intensive Group
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years and older · Female only
Enrollment
692 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
4
States / cities
Birmingham, Alabama • La Jolla, California • Aurora, Colorado + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2015 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

mFit: The Mobile Fitness Project

NCT01650337
View directory record Official record
Conditions
Overweight, Obese
Interventions
Smartphone Application
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
2
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2013 · Synced Jul 23, 2026, 2:07 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Research Study of Nutritional Methods to Reduce Body Fat Percentages in Overweight and Obese Populations

NCT00487344
View directory record Official record
Conditions
Obesity
Interventions
Non-Personalized Meal Planning, Personalized Meal Planning and Dietetic Consultation
Procedure
Lead sponsor
Central FITT, Inc
Other
Eligibility
25 Years to 45 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Edmond, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 2, 2007 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Idiopathic Intracranial Hypertension Treatment Trial

NCT01003639
View directory record Official record
Conditions
Idiopathic Intracranial Hypertension
Interventions
Acetazolamide, Placebo, Formal weight loss counselling program
Drug · Behavioral
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 60 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
39
States / cities
Birmingham, Alabama • Los Angeles, California • Waterbury, Connecticut + 31 more
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Single Arm Trial of a Multi-component Commercial Digital Weight Loss Program

NCT04302389
View directory record Official record
Conditions
Weight Loss
Interventions
myWW App, Virtual Workshops, and Private Facebook Group
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 75 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Jul 23, 2026, 2:07 AM EDT
Terminated Not applicable Interventional

Sustaining the Reach of a Scalable Weight Loss Intervention Through Financial Incentives

NCT04225234
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Financial incentives
Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 4, 2024 · Synced Jul 23, 2026, 2:07 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Weight and Shape Concern Among Women with High Body Weight

NCT05845866
View directory record Official record
Conditions
Body Image Disturbance, Overweight and Obesity, Weight Loss
Interventions
Modified Body Project, Facts about obesity, myths about weight loss, Lifestyle intervention for weight loss
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
25 Years to 70 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 29, 2025 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Phase 1Phase 2 Interventional

Omega-3 Fatty Acids in Treating Patients With Advanced Cancer Who Have Significant Weight Loss

NCT00003077
View directory record Official record
Conditions
Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
Interventions
omega-3 fatty acid
Dietary Supplement
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years to 120 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2004
U.S. locations
5
States / cities
Wilmington, Delaware • Iowa City, Iowa • Manhasset, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2016 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Medifast 5 & 1 Plan

NCT01211301
View directory record Official record
Conditions
Obesity, Body Weight, Weight Loss, Overweight, Nutrition Disorders
Interventions
Food-based, Reduced Energy Diet Plan, Medifast 5 & 1 Plan
Behavioral · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 18, 2013 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of the Effectiveness of Breakfast Recommendations On Reducing Body Weight

NCT01781780
View directory record Official record
Conditions
Obesity, Food Habits
Interventions
General Nutrition Recommendations, Breakfast Recommendation, No Breakfast Recommendation
Behavioral
Lead sponsor
David Allison, Phd
Other
Eligibility
20 Years to 65 Years
Enrollment
309 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
4
States / cities
Birmingham, Alabama • Denver, Colorado • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2014 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing the Efficacy of a Spousal Support Enhanced Weight Loss Program on Weight Loss Among African American Men

NCT02458053
View directory record Official record
Conditions
Overweight, Weight Loss, Obese
Interventions
Attends with partner, Couples Skill Training, Face to face group sessions, Self Monitor, Notebook, Feedback
Behavioral · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 13, 2017 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Not applicable Interventional

TREC Lifestyle Beyond Cancer Study in Endometrial Cancer Survivors

NCT02466061
View directory record Official record
Conditions
Endometrial Cancer
Interventions
Telemedicine Weight Management plus Wi-Fi Scale (Arm A), Text for Diet (Text4Diet) Group (Arm B), Enhanced Usual Care Group (Arm C)
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
3
States / cities
Boston, Massachusetts • St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 1, 2016 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Phase 2 Interventional

A Study of Nasal PYY3-36 and Placebo for Weight Loss in Obese Subjects

NCT00537420
View directory record Official record
Conditions
Obesity
Interventions
Nasal Placebo, Placebo Capsule, PYY3-36, Sibutramine
Drug
Lead sponsor
Nastech Pharmaceutical Company, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
551 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
29
States / cities
Peoria, Arizona • Phoenix, Arizona • Anaheim, California + 25 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2008 · Synced Jul 23, 2026, 2:07 AM EDT
Active, not recruiting Not applicable Interventional

Development of an Inclusive Adaptive Treatment Strategy for Weight Loss in People With Prediabetes Using a Sequential Multiple Assignment Randomized Trial

NCT06976307
View directory record Official record
Conditions
Disabilities, Obesity and Overweight, Prediabetes
Interventions
High Carbohydrate Diet, Reduced Carbohydrate Diet
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Jul 23, 2026, 2:07 AM EDT
Completed Not applicable Interventional

PILI at Work a 5-Year Controlled Intervention Trial: Testing DVD Versus Group Delivery of a Weight-Loss Maintenance Intervention in Native Hawaiian- Serving Worksites

NCT01652989
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss, Weight Loss Maintenance
Interventions
Weight loss maintenance intervention face-to-face, Weight loss maintenance intervention delivered via DVD
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
8
States / cities
Honolulu, Hawaii • Kailua-Kona, Hawaii • Kaunakakai, Hawaii
Source: ClinicalTrials.gov public record
Updated Dec 1, 2015 · Synced Jul 23, 2026, 2:07 AM EDT