Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 17, 2026, 8:46 AM EDT

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Showing 25–48 of 257 matching trials from the live ClinicalTrials.gov search.
Conditions
Cachexia, Neoplasms
Interventions
standard care, nutritional supplements and advice, home-based self-assisted exercise program, Ibuprofen
Other · Dietary Supplement · Behavioral + 1 more
Lead sponsor
Norwegian University of Science and Technology
Other
Eligibility
18 Years and older
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers

A Grapefruit Feeding Trial in Healthy, Overweight Adults

NCT01452841
Conditions
Weight Loss, Obesity, Cardiovascular Risk Factors
Interventions
Grapefruit, Control
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Tucson, Arizona
Completed Not applicable Interventional Accepts healthy volunteers

Improving Quality of Life in Men and Women With Overweight or Obesity

NCT04871295
Conditions
Obesity, Overweight and Obesity, Quality of Life, Health Behavior
Interventions
Noom Healthy Weight
Behavioral
Lead sponsor
Noom Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
370 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Rethinking Eating and FITness for Men

NCT01843595
Conditions
Weight Loss, Overweight
Interventions
REFIT Intervention
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

PREPARE: A Randomized Trial of a Pre-pregnancy Weight Loss Intervention

NCT02346162
Conditions
Overweight, Obese
Interventions
Weight management, Usual Care Control
Behavioral · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
326 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Not yet recruiting Not applicable Interventional

Small Changes Clinical Weight Loss Trial

NCT06668272
Conditions
Obesity
Interventions
Small Changes program, Standard behavioral therapy for weight loss
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 70 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Houston, Texas • Lubbock, Texas
Conditions
Schizophrenia, Diabetes Mellitus, Type 2, Obesity
Interventions
Naltrexone, Bupropion, Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Depression, Obesity
Interventions
Accept Yourself!, Weight Watchers
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Lebanon, New Hampshire
Conditions
Obesity
Interventions
Survodutide, Placebo
Combination Product
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
45 Years to 65 Years · Female only
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
13
States / cities
Birmingham, Alabama • Northridge, California • Walnut Creek, California + 10 more
Conditions
Disability Physical, Wheelchair, Obesity; Overweight
Interventions
The Fast In-Bed Tracking System (FIT) Weight Scale, Group Lifestyle Balance Adapted for Individuals with Impaired Mobility (GLB-AIM) intervention
Device · Behavioral
Lead sponsor
Jonathan Pearlman
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Cancer, Physical Activity, Cancer Survivorship, Mental Health, Obesity
Interventions
AYA Connect intervention, Positive Psychology (PP) intervention, Positive Psychology Plus (PP+) intervention
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 39 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Weight Loss
Interventions
PLAGB will be studied and compared to the standard LAGB procedure through a dual center, prospective clinical trial.
Procedure
Lead sponsor
Jacksonville Surgical Associates
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Ventura, California • Jacksonville, Florida
Conditions
Weight Loss
Interventions
intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
8 Years to 18 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

Randomized Controlled Clinical Trial of Weight Loss Programs in Obese Persons

NCT00960414
Conditions
Obesity
Interventions
SHINE
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
San Francisco, California
Conditions
Obesity, Multiple Chronic Conditions
Interventions
Prescriptive, Behavioral
Other · Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years to 85 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vestibular Stimulation to Trigger Adipose Loss (VeSTAL) Clinical Trial

NCT03640286
Conditions
Obesity
Interventions
VeSTAL
Device
Lead sponsor
Neurovalens Ltd.
Industry
Eligibility
22 Years to 80 Years
Enrollment
241 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
3
States / cities
La Jolla, California • Austin, Texas
Recruiting Phase 2 Interventional Accepts healthy volunteers

Cannabis for Obesity Trial

NCT06137365
Conditions
Obesity
Interventions
Cannabis, Placebo
Drug
Lead sponsor
Joshua A. Lile, Ph.D.
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Completed Not applicable Interventional Accepts healthy volunteers

CARE Trial: Comparing Different Levels of Calorie Reduction for Weight Loss

NCT02736669
Conditions
Overweight, Obesity
Interventions
Energy Reduction
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
21 Years to 75 Years
Enrollment
223 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Overweight, Obesity
Interventions
Take Shape For Life Program, Medifast Direct Program, Self-directed Control
Other
Lead sponsor
Medifast, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
198 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Addison, Illinois
Completed Not applicable Interventional

Bariatric Scalable Internet Treatments

NCT03680703
Conditions
Bariatric Surgery, Weight Loss
Interventions
Guided Self-Help Behavioral Weight Loss
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

Substituting Mushrooms for Meat to Control Body Weight

NCT01177085
Conditions
Obesity
Interventions
Weight-loss and weight-maintenance diets
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Obesity, Overweight, Prediabetes, Weight Loss, Lifestyle
Interventions
Wearable technology, smartscale, Smartphone applications, Standard Weight Management Visits
Device · Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Coached or Non-Coached Weight Loss Intervention

NCT04645108
Conditions
Obesity, Behavior, Health, Behavior, Eating, Weight Loss, Overweight and Obesity, Self Efficacy
Interventions
Noom Healthy Weight; mobile behavior change program for weight loss with 1:1 coaching, Noom Healthy Weight; mobile behavior change program for weight loss
Behavioral
Lead sponsor
Noom Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
246 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Conditions
Unintended Weight Loss
Interventions
GRAIL Galleri
Diagnostic Test
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
40 Years to 80 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio