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Showing 1–24 of 155 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Wound Closure Clear all
Completed Not applicable Interventional Results available

A Skin Glue Versus Subcuticular Suture for Cesarean Closure Study

NCT05903547
View directory record Official record
Conditions
Cesarean Section, Complication, Wound
Interventions
Dermabond Prineo, Suture
Device · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 21, 2026, 4:03 PM EDT
Withdrawn Not applicable Interventional

DuraMesh Laparotomy Closure Following Trauma and Emergency Surgery

NCT04312165
View directory record Official record
Conditions
Hernia Incisional, Suture, Complication
Interventions
Duramesh Laparotomy Closure, Conventional suture closure
Device
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Baltimore, Maryland • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Jul 21, 2026, 4:03 PM EDT
Recruiting Not applicable Interventional

Irrisept Solution for Instrumented Spine Surgery

NCT06439953
View directory record Official record
Conditions
Post-Op Complication, Spine Surgery, Site Infection, Surgical Site Infection, Spinal Instrumentation, Index Spinal Instrumentation, Layer-by-Layer Closure, Locoregional Flap-Based Closure
Interventions
Chlorhexidine gluconate solution, Vancomycin
Device · Drug
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Jul 21, 2026, 4:03 PM EDT
Completed Not applicable Interventional

Cesarean Wound Closure in Women With BMI 40 or Greater

NCT02549131
View directory record Official record
Conditions
C.Delivery; Penetration, Pregnant Uterus, by Instrument, Obesity
Interventions
Randomizing to Suture or Staple closure of Cesarean section
Procedure
Lead sponsor
Pediatrix
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
232 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
2
States / cities
Phoenix, Arizona • Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Jul 21, 2026, 4:03 PM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy Study of BondEase to Treat Traumatic Lacerations and Surgical Incisions

NCT01716013
View directory record Official record
Conditions
Traumatic Lacerations or Surgical Incisions
Interventions
BondEase, CWCD
Device · Procedure
Lead sponsor
OptMed, Inc.
Industry
Eligibility
18 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
6
States / cities
Orlando, Florida • Chicago, Illinois • Chevy Chase, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 8, 2017 · Synced Jul 21, 2026, 4:03 PM EDT
Withdrawn Not applicable Interventional

Wick vs. No Wick: Does Method of Closure Affect Rate of Wound Infection?

NCT01691352
View directory record Official record
Conditions
Postoperative Wound Infection
Interventions
Wick dressing, No Wick
Procedure
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
1 Day to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Jul 21, 2026, 4:03 PM EDT
Completed Not applicable Interventional

Aesthetic Outcome of Complex Linear Closure vs Second Intention Healing: Below the Knee

NCT05074212
View directory record Official record
Conditions
Wound Heal, Wound of Skin
Interventions
Factorial Assignment
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 21, 2026, 4:03 PM EDT
Recruiting No phase listed Observational

Acellular Collagen Matrix as a Tool to Obtain Wound Closure Following a Guided Bone Regeneration Procedure

NCT06871735
View directory record Official record
Conditions
Bone Graft
Interventions
Acellular matrix, Surgical closure
Procedure
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Jul 21, 2026, 4:03 PM EDT
Completed Phase 2 Interventional Results available

Randomized Clinical Trial of Skin Closure With Staples Versus Suture

NCT01977612
View directory record Official record
Conditions
Wound Infection, Wound Complication
Interventions
4-0 monofilament suture, Stainless steel staples
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 30, 2017 · Synced Jul 21, 2026, 4:03 PM EDT
Completed Not applicable Interventional Results available

Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers

NCT04918784
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Restrata®, Wound Dressing
Device
Lead sponsor
Acera Surgical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Hoffman Estates, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Jul 21, 2026, 4:03 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Sutures vs. Staples Skin Closure After C-section in Obese Patients

NCT01820221
View directory record Official record
Conditions
Obesity, Pregnancy
Interventions
Suture vs. staples closure method after c-section in obese women.
Procedure
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2017 · Synced Jul 21, 2026, 4:03 PM EDT
Terminated Not applicable Interventional Results available

Celliant Socks to Increase Tissue Oxygenation and Complete Wound Closure in Diabetic Foot Wounds

NCT04709419
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Celliant Diabetic Medical Socks, Control (placebo) Medical Socks
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
22 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Jul 21, 2026, 4:03 PM EDT
Completed Not applicable Interventional Results available

A Study Investigating the Efficacy of Various Wound Closure Devices in Reducing Postoperative Wound Complications

NCT03134209
View directory record Official record
Conditions
Joint Disease, Arthropathy
Interventions
Zipper surgical skin closure, Monocryl + Dermabond, Polyester mesh + Dermabond
Device · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Jul 21, 2026, 4:03 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparison of Adhesive Latch Device to Subcuticular Skin Closure at the Time of Cesarean Section

NCT03052647
View directory record Official record
Conditions
Wound
Interventions
Dermaclip, Subcuticular suture
Device
Lead sponsor
Rubino Ob-Gyn Group
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 14, 2017 · Synced Jul 21, 2026, 4:03 PM EDT
Completed Not applicable Interventional

Wound Eversion Versus Planar Closure for Face or Neck Wounds

NCT03302988
View directory record Official record
Conditions
Operative Wound
Interventions
Everted closure, Planar closure
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2018 · Synced Jul 21, 2026, 4:03 PM EDT
Completed Not applicable Interventional Results available

Vacuum Assisted Closure as a Treatment for Open Fractures

NCT00582361
View directory record Official record
Conditions
Orthopaedic Traumatic Open Fractures
Interventions
Standard Wound Dressing, VAC
Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2010
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 13, 2013 · Synced Jul 21, 2026, 4:03 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Prevena Spine for Use in Spine Surgery

NCT05555355
View directory record Official record
Conditions
Surgery, Incision, Surgical
Interventions
Prevena Plus 125 Therapy Unit, Spine surgery
Device · Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Jul 21, 2026, 4:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Alveolar Ridge Preservation Procedures

NCT05419778
View directory record Official record
Conditions
Alveolar Ridge Preservation
Interventions
Osteogen plug®, MInerOss®
Device
Lead sponsor
University of Tennessee
Other
Eligibility
12 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 7, 2022 · Synced Jul 21, 2026, 4:03 PM EDT
Active, not recruiting Not applicable Interventional

Suture Versus Staples for Wound Closure in Orthopaedic Trauma Surgery

NCT06586814
View directory record Official record
Conditions
Lower Extremity Fracture
Interventions
Suture, Staple
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jul 21, 2026, 4:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Laparoscopic Incision Closure s in Obese Patients

NCT05622110
View directory record Official record
Conditions
Obesity, Incision, Surgical
Interventions
Adhesive glue closure, Subcuticular closure
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 7, 2025 · Synced Jul 21, 2026, 4:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Use of Insorb Absorbable Vicryl Staples in Skin Closure for Cesarean Section

NCT01446627
View directory record Official record
Conditions
Wound Infection
Interventions
There is no intervention for this study
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
14 Years to 50 Years · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 2, 2013 · Synced Jul 21, 2026, 4:03 PM EDT
Completed Not applicable Interventional

LiquiBand® Exceed™ and LiquiBand® Rapid™ for General Surgery Procedures

NCT04740775
View directory record Official record
Conditions
Surgical Wound
Interventions
LiquiBand Exceed, LiquiBand Rapid
Device
Lead sponsor
Advanced Medical Solutions Ltd.
Industry
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
4
States / cities
Columbus, Ohio • Greenville, South Carolina • Greer, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Jul 21, 2026, 4:03 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Wound Closure Study in Carpal Tunnel and Trigger Finger Surgery

NCT03781141
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Trigger Finger
Interventions
Wound closure
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jul 21, 2026, 4:03 PM EDT
Recruiting Phase 3 Interventional

Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Burn Wounds as an Alternative to Autografting

NCT06223269
View directory record Official record
Conditions
Burns Degree Third, Burn (Disorder), Burn Degree Second, Thermal Burn, Wound Heal
Interventions
Skin Xenotransplant, Autograft(ing)
Drug · Procedure
Lead sponsor
XenoTherapeutics, Inc.
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Phoenix, Arizona • Augusta, Georgia • Portland, Maine + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Jul 21, 2026, 4:03 PM EDT