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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Wound Closure Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Outcomes Comparing Different Methods of Skin Closure in Patients Undergoing Head and Neck Surgery.

NCT02936063
View directory record Official record
Conditions
Surgical Wound
Interventions
Surgical staples, Subcuticular sutures
Procedure
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Sep 15, 2026, 10:26 AM EDT
Enrolling by invitation Not applicable Interventional

Dyed vs. Undyed Polyglactin Sutures in Cutaneous Surgery

NCT07078669
View directory record Official record
Conditions
Wound Closure, Suture Materials
Interventions
Polyglactin 910 (Dyed), Polyglactin 910 (Undyed)
Device
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Waynesburg, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Sep 15, 2026, 10:26 AM EDT
Terminated Not applicable Interventional Results available

Prevention of Wound Complications After Cesarean Delivery in Obese Women Utilizing Negative Pressure Wound Therapy

NCT00654641
View directory record Official record
Conditions
Surgical Wound Dehiscence, Wound Infection
Interventions
Negative pressure wound closure, Standard wound closure
Procedure
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Charleston, West Virginia • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Jan 29, 2013 · Synced Sep 15, 2026, 10:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Alveolar Ridge Preservation Procedures

NCT05419778
View directory record Official record
Conditions
Alveolar Ridge Preservation
Interventions
Osteogen plug®, MInerOss®
Device
Lead sponsor
University of Tennessee
Other
Eligibility
12 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 7, 2022 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional Results available

RESPECT Trial - (Rapid Extravascular Sealing Via PercutanEous Collagen ImplanT)

NCT01297322
View directory record Official record
Conditions
Surgical Wound
Interventions
Manual compression, Cardiva VASCADE™ Vascular Closure System
Other · Device
Lead sponsor
Cardiva Medical, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
20
States / cities
Fairhope, Alabama • Newark, Delaware • Melbourne, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Collection and Application of Autologous Amniotic Fluid At Cesarean Delivery Closure.

NCT04359472
View directory record Official record
Conditions
Pregnancy Related, Cesarean Wound Disruption, Cesarean Section; Infection
Interventions
Application of Autologous Amniotic Fluid
Device
Lead sponsor
Recibio, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of Knotless Suture for Closure of Total Hip and Knee Arthroplasties

NCT00834483
View directory record Official record
Conditions
Knee Osteoarthritis, Hip Osteoarthritis
Interventions
Knotless suture for wound closure, Layered traditional wound closure (monocryl)
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 10, 2014 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional

Closure of Patent Ductus Arteriosus With Indomethacin or Ibuprofen in Extreme Low Birth Weight Infants

NCT01758913
View directory record Official record
Conditions
Patent Ductus Arteriosus
Interventions
Ibuprofen
Drug
Lead sponsor
Taipei Medical University Hospital
Other
Eligibility
Up to 6 Months
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 2, 2013 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional

Prospective Randomized Trial of Monocryl Versus Nylon Suture Closure in Carpal Tunnel Surgery

NCT03950401
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Monocryl, Nylon
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 20, 2021 · Synced Sep 15, 2026, 10:26 AM EDT
Recruiting Not applicable Interventional

Miro3D Wound Matrix for Treatment of Diabetic Foot Ulcers

NCT07632001
View directory record Official record
Conditions
Diabetic Foot Ulcers (DFUs), Diabetic Foot, Chronic Wounds
Interventions
Miro3D Wound Matrix, Standard of Care
Device · Other
Lead sponsor
Reprise Biomedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
14
States / cities
Phoenix, Arizona • Coconut Creek, Florida • Coral Gables, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 15, 2026, 10:26 AM EDT
Terminated Not applicable Interventional Results available

Secondary Versus Tertiary Wound Closure in High Risk Gynecologic Abdominal Surgical Incisions

NCT03861065
View directory record Official record
Conditions
Surgical Incision
Interventions
Tertiary Wound Closure, Historical Wound Closure
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Phase 1 Interventional

A Comparison Of The 3M TM S Surgical Skin Closure System To The Standard Vicryl Suture Closure of Sternotomy Incisions During Cardiac Surgery

NCT00576745
View directory record Official record
Conditions
Wound Infection
Interventions
Vicryl Suture, 3M TM S Surgical Skin Closure System
Procedure · Device
Lead sponsor
American Heart Association
Other
Eligibility
18 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 17, 2012 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional

BandGrip® Closure of Surgical Incisions Following Arthroscopic Surgery

NCT03644316
View directory record Official record
Conditions
Surgical Incision
Interventions
BandGrip skin closure device
Device
Lead sponsor
BandGrip
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Phase 2 Interventional

Multi-center Study to Assess Safety, Tolerability and Efficacy of Topical Pravibismane in Moderate DFI Patients

NCT05174806
View directory record Official record
Conditions
Diabetic Foot Infection, Diabetic Foot
Interventions
Topical Pravibismane, Standard of Care
Drug · Other
Lead sponsor
Microbion Corporation
Industry
Eligibility
18 Years to 79 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
7
States / cities
Fresno, California • Dallas, Texas • McAllen, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2024 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional

LiquiBand Versus Dermabond Versus Sutures for Closure of Surgical Wounds

NCT01835405
View directory record Official record
Conditions
Surgical Incisions
Interventions
LiquiBand Flex, Dermabond Advanced, Sutures (Prolene)
Device
Lead sponsor
Advanced Medical Solutions Ltd.
Industry
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Beverly, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Sep 15, 2026, 10:26 AM EDT
Recruiting Not applicable Interventional

Aesthetic Outcome of Intra-dermal Versus Transcutaneous Purse-string Closure

NCT06448481
View directory record Official record
Conditions
Scarring
Interventions
Intra-dermal purse-string closure, Transcutaneous purse-string closure
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 15, 2026, 10:26 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Closure After Total Shoulder Arthroplasty: Prineo vs Dermabond

NCT03899753
View directory record Official record
Conditions
Shoulder Arthritis, Shoulder Arthropathy Associated With Other Conditions
Interventions
2-Octyl Cyanoacrylate and Mesh, 2-Octyl Cyanoacrylate
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional

Aesthetic Outcome of Layered Closure vs. Layered Closure Followed by 2-Octyl Cyanoacrylate

NCT05449457
View directory record Official record
Conditions
Scarring
Interventions
2-Octyl cyanoacrylate
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional

A Study Assessing Circulation Around Surgical Incisions at the Time of Laparotomy Closure

NCT03408366
View directory record Official record
Conditions
Laparotomy
Interventions
Laparotomy, ICG, Spectrum NIR imaging system
Procedure · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
8
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2022 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional Results available

Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries

NCT00582998
View directory record Official record
Conditions
Fracture of Calcaneus, Pilon or Tibial Plateau
Interventions
Standard Wound Dressing, Vacuum Assisted Closure Device
Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional Results available

Randomized, Controlled Multicenter Trial of Vacuum Assisted Closure Therapy™ in Diabetic Foot Ulcers

NCT00432965
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
Moist Wound Therapy, VAC Therapy
Device
Lead sponsor
KCI USA, Inc
Industry
Eligibility
18 Years and older
Enrollment
335 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
24
States / cities
Phoenix, Arizona • Tucson, Arizona • Castro Valley, California + 17 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Sep 15, 2026, 10:26 AM EDT
Not yet recruiting Not applicable Interventional

Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT

NCT06043414
View directory record Official record
Conditions
Laparotomy, Dehiscence Wound, Surgical Site Infections, Trauma Abdomen, Emergency General Surgery
Interventions
triclosan-coated barbed suture, triclosan-coated non-barbed suture, Non-coated non-barbed suture
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 100 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional

Post Operative Skin Approximation With Cyanoacrylate Based Wound Closure Adhesives

NCT07613892
View directory record Official record
Conditions
Wound Closure, Dehisced Surgical Wounds
Interventions
Evaluating wound closure products to close larger surgical site incisions, Evaluating wound closure products to close smaller surgical site incisions
Device
Lead sponsor
Medline Industries
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Johnstown, Colorado
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 15, 2026, 10:26 AM EDT
Suspended Not applicable Interventional

Bandgrip vs Traditional Sutures TJA

NCT05166642
View directory record Official record
Conditions
Osteoarthritis
Interventions
Bandgrip Micro-Anchor Wound Closure, Suture closure
Device
Lead sponsor
Center for Innovation and Research Organization
Network
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 10, 2023 · Synced Sep 15, 2026, 10:26 AM EDT