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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Wound Closure Techniques Clear all
Withdrawn Not applicable Interventional

Wick vs. No Wick: Does Method of Closure Affect Rate of Wound Infection?

NCT01691352
View directory record Official record
Conditions
Postoperative Wound Infection
Interventions
Wick dressing, No Wick
Procedure
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
1 Day to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Not applicable Interventional

Aesthetic Outcome of Complex Linear Closure vs Second Intention Healing: Below the Knee

NCT05074212
View directory record Official record
Conditions
Wound Heal, Wound of Skin
Interventions
Factorial Assignment
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 21, 2026, 5:30 PM EDT
Recruiting No phase listed Observational

Acellular Collagen Matrix as a Tool to Obtain Wound Closure Following a Guided Bone Regeneration Procedure

NCT06871735
View directory record Official record
Conditions
Bone Graft
Interventions
Acellular matrix, Surgical closure
Procedure
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Jul 21, 2026, 5:30 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Sutures vs. Staples Skin Closure After C-section in Obese Patients

NCT01820221
View directory record Official record
Conditions
Obesity, Pregnancy
Interventions
Suture vs. staples closure method after c-section in obese women.
Procedure
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2017 · Synced Jul 21, 2026, 5:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Alveolar Ridge Preservation Procedures

NCT05419778
View directory record Official record
Conditions
Alveolar Ridge Preservation
Interventions
Osteogen plug®, MInerOss®
Device
Lead sponsor
University of Tennessee
Other
Eligibility
12 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 7, 2022 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Not applicable Interventional

LiquiBand® Exceed™ and LiquiBand® Rapid™ for General Surgery Procedures

NCT04740775
View directory record Official record
Conditions
Surgical Wound
Interventions
LiquiBand Exceed, LiquiBand Rapid
Device
Lead sponsor
Advanced Medical Solutions Ltd.
Industry
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
4
States / cities
Columbus, Ohio • Greenville, South Carolina • Greer, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Jul 21, 2026, 5:30 PM EDT
Recruiting Phase 4 Interventional

Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures

NCT07225101
View directory record Official record
Conditions
Wound Closure, Brain Tumor Adult, Spine, Neurovascular, Hemorrhagic Stroke, Intracerebral, Traumatic Brain Injury
Interventions
STRATAFIX PDS and Monocryl suture
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Not applicable Interventional Results available

RESPECT Trial - (Rapid Extravascular Sealing Via PercutanEous Collagen ImplanT)

NCT01297322
View directory record Official record
Conditions
Surgical Wound
Interventions
Manual compression, Cardiva VASCADE™ Vascular Closure System
Other · Device
Lead sponsor
Cardiva Medical, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
20
States / cities
Fairhope, Alabama • Newark, Delaware • Melbourne, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Phase 4 Interventional Results available

A Comparison of Polyglactin 910 and Chromic Gut Suture in the Closure of Punch Biopsy Sites

NCT01722994
View directory record Official record
Conditions
Wound Closure Technique
Interventions
Polyglactin 910 sterile synthetic absorbable suture (Ethicon), Chromic Gut Sterile absorbable Suture (Ethicon)
Device
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Mar 1, 2016 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Not applicable Interventional

Evaluation of Purse-String Closure Vs Second Intention

NCT02062866
View directory record Official record
Conditions
Wound Closure Techniques
Interventions
Purse-String, Second Intent
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2015 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparative Study of Incision Closure Methods for Total Knee Replacement

NCT01088074
View directory record Official record
Conditions
Total Knee Replacement Closure, Wound Closure
Interventions
Histoacryl Tissue Adhesive, Dermabond, Staples, Monocryl 4-0
Device
Lead sponsor
Foundation for Southwest Orthopedic Research
Other
Eligibility
21 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 21, 2012 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Not applicable Interventional Results available

An Analysis of Dermabond vs. Non-Absorbable Sutures in Skin Closure for Brow Ptosis Procedures

NCT05981443
View directory record Official record
Conditions
Brow Ptosis, Surgical Wound
Interventions
Dermabond, Non-Absorbable Sutures
Device · Other
Lead sponsor
Cody Blanchard
Other
Eligibility
18 Years to 100 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Clinical Trial Comparing Standard Wound Closure Techniques Versus TissuGlu® Surgical Adhesive

NCT01791504
View directory record Official record
Conditions
Disorder of Skin and/or Subcutaneous Tissue of Trunk
Interventions
TissuGlu Surgical Adhesive
Device
Lead sponsor
Cohera Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Huntersville, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 4, 2013 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Not applicable Interventional

Comparison of Cosmetic Outcomes of Straight Line and W-plasty Techniques for Linear Wound Closure

NCT05074199
View directory record Official record
Conditions
Suture Dermatologic, Surgery, Cosmetic Outcome
Interventions
W-plasty/Linear closure
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Jul 21, 2026, 5:30 PM EDT
Enrolling by invitation Not applicable Interventional

Rate of Allergic Contact Dermatitis and Cosmetic Outcomes

NCT06957444
View directory record Official record
Conditions
Allergic Contact Dermatitis, Osteoarthritis, Hip, Osteoarthritis, Knee
Interventions
Sylke Adhesive Dressing, Exofin Skin Glue, Suture Strip Plus
Procedure
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 80 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Not applicable Interventional Results available

Orthopaedic Surgical Wound Closure Comparison Study

NCT05251064
View directory record Official record
Conditions
Incision, Surgical
Interventions
Suture, Clozex, Zipline
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 14, 2025 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Early Phase 1 Interventional

Closure Method Study Following Tonsillectomy in Children

NCT00730340
View directory record Official record
Conditions
Tonsillectomy, Children
Interventions
Closure of the Tonsillar Fossa, Tonsillectomy with open fossa
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
5 Years to 10 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 14, 2010 · Synced Jul 21, 2026, 5:30 PM EDT
Terminated Not applicable Interventional Results available

Comparison Study of Wound Closure at Time of Cesarean Delivery: Dermabond Glue Versus Surgical Staples

NCT00524511
View directory record Official record
Conditions
Cesarean Section
Interventions
Surgical skin staples, Dermabond
Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
Female only
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 4, 2013 · Synced Jul 21, 2026, 5:30 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Wound Closure Techniques

NCT00282633
View directory record Official record
Conditions
Wounds, Closure
Interventions
Dermabond
Device
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 30, 2007 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: Vacuum Assisted Closure (VAC) and Gauze Suction (GSUC)

NCT00952120
View directory record Official record
Conditions
Wound Healing
Interventions
GSUC, VAC
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced Jul 21, 2026, 5:30 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Outcomes Comparing Different Methods of Skin Closure in Patients Undergoing Head and Neck Surgery.

NCT02936063
View directory record Official record
Conditions
Surgical Wound
Interventions
Surgical staples, Subcuticular sutures
Procedure
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Not applicable Interventional

A Randomized Trial of Ostomy Closure Techniques

NCT01713452
View directory record Official record
Conditions
Wound Infection
Interventions
Purse string closure, Primary closure
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Skin Closure With Tissue Adhesives vs. Subcuticular Suture After Robotic Urogynecologic Procedures

NCT03891004
View directory record Official record
Conditions
Surgical Wound, Tissue Adhesion
Interventions
Subcuticular Skin Closure, Tissue Adhesives
Procedure · Device
Lead sponsor
St. John Hospital & Medical Center
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 3, 2019 · Synced Jul 21, 2026, 5:30 PM EDT
Completed Not applicable Interventional Results available

The Closer Trial: A Safety and Efficacy Study of the Rex Medical Vascular Sealing System

NCT02136004
View directory record Official record
Conditions
Surgical Wound
Interventions
Closer VSS
Device
Lead sponsor
Rex Medical
Industry
Eligibility
18 Years to 80 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
12
States / cities
Sacramento, California • Englewood, Colorado • Washington D.C., District of Columbia + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Jul 21, 2026, 5:30 PM EDT