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ClinicalTrials.gov public records Last synced Jul 22, 2026, 5:59 AM EDT

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Showing 25–46 of 22 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Xenotransplantation Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Root Coverage Comparing an Allograft to a Bovine Xenograft

NCT02810067
View directory record Official record
Conditions
Gingival Recession
Interventions
Tunnel + AlloDerm, Tunnel + Novomatrix
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 17, 2018 · Synced Jul 22, 2026, 5:59 AM EDT
Recruiting No phase listed Observational

Development of Patient Derived Xenografts (PDX) in Patients With Breast Cancer

NCT04703244
View directory record Official record
Conditions
Breast Cancer, Residual
Interventions
chemotherapy or endocrine therapy for breast cancer
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
999 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2042
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Jul 22, 2026, 5:59 AM EDT
Not yet recruiting Phase 1 Interventional

Study of ChoironeX GalKO Porcine Thymokidney Xenotransplantation in End-Stage Renal Disease

NCT07696962
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
ChoironeX GalKO Porcine Thymokidney
Biological
Lead sponsor
Xeno Holdings (US), LLC dba ChoironeX
Industry
Eligibility
18 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 22, 2026, 5:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ridge Preservation Comparing an Intrasocket Graft Alone to an Intrasocket Graft Plus a Facial Overlay Graft

NCT01431131
View directory record Official record
Conditions
Clinical Efficacy
Interventions
Intrasocket graft, Intrasocket plus facial overlay graft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 30, 2017 · Synced Jul 22, 2026, 5:59 AM EDT
Withdrawn Not applicable Interventional

OrthoPure™ XT Pilot Clinical Study

NCT03562299
View directory record Official record
Conditions
Knee Injuries, Anterior Cruciate Ligament (ACL) Reconstruction
Interventions
OrthoPure™ XT
Device
Lead sponsor
TRX Orthopedics
Industry
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Phoenix, Arizona • Greenwood, Indiana • Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Jul 22, 2026, 5:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ridge Preservation Comparing 2 Membranes

NCT01905280
View directory record Official record
Conditions
Alveolar Ridge Deficiency
Interventions
Non-resorbable membrane, Acellular dermal matrix
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Jul 22, 2026, 5:59 AM EDT
Recruiting Phase 1Phase 2 Interventional

Study to Evaluate the Safety and Efficacy of the 10 GE Xenokidney in Patients With ESRD

NCT06878560
View directory record Official record
Conditions
ESRD (End-Stage Renal Disease), Kidney Transplantation, Xenotransplantation
Interventions
10 GE Xenokidney
Biological
Lead sponsor
United Therapeutics
Industry
Eligibility
40 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2075
U.S. locations
2
States / cities
Chicago, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jul 22, 2026, 5:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Demineralized Bone Allograft Fibers Versus Particulate In Sinus Augmentation

NCT06173791
View directory record Official record
Conditions
Bone Loss in Jaw
Interventions
DFDBA fibers, DFDBA particles, DBBM
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 89 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Jul 22, 2026, 5:59 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effect of Alveolar Ridge Preservation After Tooth Extraction in the Posterior Maxilla

NCT02952209
View directory record Official record
Conditions
Tooth Extraction
Interventions
Xenograft
Device
Lead sponsor
NYU College of Dentistry
Other
Eligibility
20 Years to 90 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 8, 2021 · Synced Jul 22, 2026, 5:59 AM EDT
Completed Not applicable Interventional Results available

Tissue and Hematopoietic/Mesenchymal Stem Cell for Humanized Xenograft Studies in Melanoma and Squamous Head and Neck Cancer

NCT02331134
View directory record Official record
Conditions
Malignant Melanoma, Head and Neck Cancer
Interventions
Filgrastim
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Jul 22, 2026, 5:59 AM EDT
Completed No phase listed Observational

Patient-derived Xenograft (PDX) Modeling of Treatment Response for Triple Negative Breast Cancer

NCT02247037
View directory record Official record
Conditions
Triple Negative Breast Cancer
Interventions
Chemotherapy
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 90 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 6, 2020 · Synced Jul 22, 2026, 5:59 AM EDT
Completed Phase 4 Interventional

A Randomized, Controlled Trial of the Effectiveness of Perioperative Antibiotics for Reduction of Burn Wound Bacterial Concentration Following Grafting

NCT04516148
View directory record Official record
Conditions
Burn, Surgery, Infection Wound
Interventions
Cefazolin, Clindamycin
Drug
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Jul 22, 2026, 5:59 AM EDT
Completed Not applicable Interventional Results available

An RCT Comparing Xenograft and Allograft for Ridge Preservation

NCT02330523
View directory record Official record
Conditions
Tooth Loss
Interventions
allograft + x-link collagen membrane, xenograft + non-x-link collagen
Device
Lead sponsor
McGuire Institute
Industry
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 17, 2016 · Synced Jul 22, 2026, 5:59 AM EDT
Not listed No phase listed Observational

Patient-Derived Xenografts to Reduce Cancer Health Disparities

NCT04410302
View directory record Official record
Conditions
Bladder Carcinoma, Gastric Carcinoma, Liver and Intrahepatic Bile Duct Carcinoma, Lung Carcinoma, Malignant Neoplasm
Interventions
Biospecimen Collection
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
21 Years to 100 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Orange, California • Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 15, 2023 · Synced Jul 22, 2026, 5:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Post Tooth Extraction Healing Using Different Xenograft Materials

NCT03149172
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
Equimatrix®, Bio-Oss®, Endobon®
Device
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 24, 2020 · Synced Jul 22, 2026, 5:59 AM EDT
Withdrawn Phase 1 Interventional

Porcine Kidney Xenotransplantation in Patients With End-Stage Kidney Disease

NCT05340426
View directory record Official record
Conditions
Kidney Failure, Chronic
Interventions
UKidney
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Jul 22, 2026, 5:59 AM EDT
Completed No phase listed Observational

Methods Validation Assessment for Study of Inflammatory Skin Disease

NCT03796806
View directory record Official record
Conditions
Lichen Planus
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Jul 22, 2026, 5:59 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Retrospective Case Series - OSSIX Volumax Collagen Xenograft Scaffolding

NCT06187805
View directory record Official record
Conditions
Dental Implants
Interventions
OSSIX Volumax
Device
Lead sponsor
Old Orchard Periodontics and Implant Dentistry LTD
Other
Eligibility
18 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Skokie, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 4, 2024 · Synced Jul 22, 2026, 5:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Histologic Comparison of Healing After Tooth Extraction With Ridge Preservation Using Two Different Xenografts

NCT03769376
View directory record Official record
Conditions
Partial Edentulism
Interventions
Bio-Oss®, Salvin-Oss®
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 100 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Jul 22, 2026, 5:59 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vallomix Socket Preservation Study

NCT06472453
View directory record Official record
Conditions
Alveolar Ridge Augmentation
Interventions
Allograft/Xenograft, Allograft
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Jul 22, 2026, 5:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Clinical Effect of Implant Placement With a Simultaneous Soft Tissue Allograft

NCT02139748
View directory record Official record
Conditions
Dental Implants
Interventions
Dental Implant & ADM, Dental Implant & ADM & bone xenograft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Jul 22, 2026, 5:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ridge Preservation Comparing the Healing With or Without a Barrier Membrane

NCT02798887
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
Ridge preservation
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced Jul 22, 2026, 5:59 AM EDT