ClinicalTrials.gov record
Completed Phase 3 Interventional

Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia

ClinicalTrials.gov ID: NCT00002816

Public ClinicalTrials.gov record NCT00002816. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 10:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

EXTRAMEDULLARY RELAPSE AND OCCULT BONE MARROW INVOLVEMENT IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA: A PHASE III GROUP-WIDE STUDY

Study identification

NCT ID
NCT00002816
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Children's Oncology Group
Network
Enrollment
120 participants

Conditions and interventions

Conditions

Interventions

  • Methotrexate Drug
  • cytarabine Drug
  • dexamethasone Drug
  • etoposide Drug
  • idarubicin Drug
  • ifosfamide Drug
  • leucovorin calcium Drug
  • low-LET cobalt-60 gamma ray therapy Radiation
  • low-LET electron therapy Radiation
  • low-LET photon therapy Radiation
  • mesna Drug
  • pegaspargase Drug
  • therapeutic hydrocortisone Drug
  • thioguanine Drug
  • vincristine sulfate Drug

Drug · Radiation

Eligibility (public fields only)

Age range
Up to 20 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 1996
Primary completion
Oct 31, 2002
Completion
Mar 31, 2006
Last update posted
Aug 21, 2013

1996 – 2006

United States locations

U.S. sites
30
U.S. states
19
U.S. cities
26
Facility City State ZIP Site status
Long Beach Memorial Medical Center Long Beach California 90806
Children's Hospital Los Angeles Los Angeles California 90027-0700
Jonsson Comprehensive Cancer Center, UCLA Los Angeles California 90095-1781
Children's Hospital of Orange County Orange California 92668
UCSF Cancer Center and Cancer Research Institute San Francisco California 94115-0128
Children's Hospital of Denver Denver Colorado 80218
Children's National Medical Center Washington D.C. District of Columbia 20010-2970
University of Chicago Cancer Research Center Chicago Illinois 60637
Indiana University Cancer Center Indianapolis Indiana 46202-5265
University of Iowa Hospitals and Clinics Iowa City Iowa 52242
University of Michigan Comprehensive Cancer Center Ann Arbor Michigan 48109-0752
University of Minnesota Cancer Center Minneapolis Minnesota 55455
Mayo Clinic Cancer Center Rochester Minnesota 55905
Children's Mercy Hospital - Kansas City Kansas City Missouri 64108
University of Nebraska Medical Center Omaha Nebraska 68198-3330
Kaplan Cancer Center New York New York 10016
Memorial Sloan-Kettering Cancer Center New York New York 10021
Herbert Irving Comprehensive Cancer Center New York New York 10032
Lineberger Comprehensive Cancer Center, UNC Chapel Hill North Carolina 27599-7295
Children's Hospital Medical Center - Cincinnati Cincinnati Ohio 45229-3039
Ireland Cancer Center Cleveland Ohio 44106-5065
Children's Hospital of Columbus Columbus Ohio 43205-2696
Doernbecher Children's Hospital Portland Oregon 97201-3098
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
Children's Hospital of Pittsburgh Pittsburgh Pennsylvania 15213
Vanderbilt Cancer Center Nashville Tennessee 37232-6838
Huntsman Cancer Institute Salt Lake City Utah 84132
Children's Hospital and Regional Medical Center - Seattle Seattle Washington 98105
Fred Hutchinson Cancer Research Center Seattle Washington 98109
University of Wisconsin Comprehensive Cancer Center Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00002816, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 21, 2013 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00002816 live on ClinicalTrials.gov.

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