Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumor
Public ClinicalTrials.gov record NCT00003273. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Dose Intensive Chemotherapy for Children Less Than Ten Years of Age Newly-Diagnosed With Malignant Brain Tumors: A Pilot Study of Two Alternative Intensive Induction Chemotherapy Regimens, Followed by Consolidation With Myeloablative Chemotherapy (Thiotepa, Etoposide and Carboplatin) and Autologous Stem Cell Rescue
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of different regimens of combination chemotherapy followed by peripheral stem cell transplantation in treating children who have newly diagnosed brain tumor.
Study identification
- NCT ID
- NCT00003273
- Recruitment status
- Withdrawn
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- Not listed
Conditions and interventions
Interventions
- filgrastim Biological
- carboplatin Drug
- cisplatin Drug
- cyclophosphamide Drug
- etoposide Drug
- leucovorin calcium Drug
- methotrexate Drug
- temozolomide Drug
- thiotepa Drug
- vincristine sulfate Drug
- autologous bone marrow transplantation Procedure
- peripheral blood stem cell transplantation Procedure
- radiation therapy Radiation
Biological · Drug · Procedure + 1 more
Eligibility (public fields only)
- Age range
- Up to 10 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 1997 (Type not available)
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Dec 3, 2015
Started 1997
United States locations
- U.S. sites
- 17
- U.S. states
- 9
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813 | — |
| Maine Children's Cancer Program | Scarborough | Maine | 04074-9308 | — |
| Spectrum Health and DeVos Children's Hospital | Grand Rapids | Michigan | 49503 | — |
| Children's Hospital of Omaha | Omaha | Nebraska | 68114 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| NYU School of Medicine's Kaplan Comprehensive Cancer Center | New York | New York | 10016 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | — |
| Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | — |
| Beth Israel Hospital North | New York | New York | 10128 | — |
| State University of New York Health Sciences Center - Stony Brook | Stony Brook | New York | 11790-7775 | — |
| State University of New York - Upstate Medical University | Syracuse | New York | 13210 | — |
| Albert Einstein Clinical Cancer Center | The Bronx | New York | 10461 | — |
| St. Vincent Mercy Medical Center | Toledo | Ohio | 43608 | — |
| Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | 53792-6164 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003273, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 3, 2015 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00003273 live on ClinicalTrials.gov.