Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia
Public ClinicalTrials.gov record NCT00003619. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase I/II Combination Study of Topotecan, Fludarabine, Cytosine Arabinoside and G-CSF (T-FLAG) Induction Therapy in Patients With Poor Prognosis AML, MDS and Relapsed/Refractory ALL Followed by Maintenance of Either PBSC Transplant or 13 Cis-Retinoic Acid
Study identification
- NCT ID
- NCT00003619
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Drexel University College of Medicine
- Other
- Enrollment
- Not listed
Conditions and interventions
Interventions
- bone marrow ablation with stem cell support Procedure
- busulfan Drug
- cytarabine Drug
- etoposide Drug
- filgrastim Biological
- fludarabine phosphate Drug
- isotretinoin Drug
- peripheral blood stem cell transplantation Procedure
- topotecan hydrochloride Drug
- vitamin E Dietary Supplement
Procedure · Drug · Biological + 1 more
Eligibility (public fields only)
- Age range
- 19 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 1998
- Primary completion
- Not listed
- Completion
- Mar 31, 2004
- Last update posted
- Jun 25, 2013
1998 – 2004
United States locations
- U.S. sites
- 2
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Medical College of Pennsylvania Hospital | Philadelphia | Pennsylvania | 19129 | — |
| Medical College of Pennsylvania | Philadelphia | Pennsylvania | 19129 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003619, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 25, 2013 · Synced May 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00003619 live on ClinicalTrials.gov.