Combination Chemotherapy in Treating Patients With Bladder Cancer
Public ClinicalTrials.gov record NCT00003701. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized Trial of Either M-VAC or Paclitaxel + Carboplatin as Postoperative Adjuvant Therapy in Patients With Muscle-Invasive Transitional Cell Carcinoma of the Bladder at High-Risk for Relapse
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known whether four-drug combination chemotherapy is more effective than two-drug combination chemotherapy in treating bladder cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of two combination chemotherapy regimens in treating patients who have bladder cancer.
Study identification
- NCT ID
- NCT00003701
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 490 participants
Conditions and interventions
Conditions
Interventions
- carboplatin Drug
- cisplatin Drug
- doxorubicin hydrochloride Drug
- methotrexate Drug
- paclitaxel Drug
- vinblastine sulfate Drug
Drug
Eligibility (public fields only)
- Age range
- 0 Years to 120 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 1, 1999
- Primary completion
- Jul 31, 2001
- Completion
- Jun 14, 2007
- Last update posted
- Jun 14, 2023
1999 – 2007
United States locations
- U.S. sites
- 13
- U.S. states
- 7
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Veterans Affairs Medical Center - Atlanta (Decatur) | Decatur | Georgia | 30033 | — |
| Indiana University Hospitals | Indianapolis | Indiana | 46202 | — |
| Hunterdon Regional Cancer Center | Flemington | New Jersey | 08822 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| South Jersey Hospital - Millville | Millville | New Jersey | 08332 | — |
| Fox Chase Cancer Center at Virtua-Memorial Hospital Burlington County | Mount Holly | New Jersey | 08060 | — |
| Riverview Medical Center | Red Bank | New Jersey | 07701 | — |
| Overlook Hospital | Summit | New Jersey | 07902-0220 | — |
| Veterans Affairs Medical Center - New York | New York | New York | 10010 | — |
| NYU School of Medicine's Kaplan Comprehensive Cancer Center | New York | New York | 10016 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| Hahnemann University Hospital | Philadelphia | Pennsylvania | 19102-1192 | — |
| Vanderbilt Cancer Center | Nashville | Tennessee | 37232-6838 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003701, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 14, 2023 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00003701 live on ClinicalTrials.gov.