Surgery With or Without Chemotherapy in Treating Patients With Newly Diagnosed or Recurrent Bladder Cancer
Public ClinicalTrials.gov record NCT00003725. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase III Randomized Study of a Single Adjunctive Instillation of Intravesical AD 32 (N-Trifluoroacetyladriamycin-14-valerate) Versus No Adjunctive Therapy Immediately Following Transurethral Resection in Patients With Multiple Superficial (Ta/T1) Bladder Tumors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Transurethral resection is a less invasive type of surgery for bladder cancer and may have fewer side effects and improve recovery. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether transurethral resection plus AD 32 is more effective than transurethral resection alone for bladder cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of transurethral resection surgery followed by AD 32 with that of transurethral resection alone in treating patients who have newly diagnosed or recurrent bladder cancer.
Study identification
- NCT ID
- NCT00003725
- Recruitment status
- Not listed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 300 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 1996 (Type not available)
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Nov 6, 2013
Started 1996
United States locations
- U.S. sites
- 51
- U.S. states
- 28
- U.S. cities
- 46
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Urology Associates | Birmingham | Alabama | 35205 | — |
| Urology Associates, Ltd. | Phoenix | Arizona | 85012 | — |
| University of California San Diego Cancer Center | La Jolla | California | 92093-0658 | — |
| San Diego Urology Center | La Mesa | California | 91942 | — |
| Hillcrest Urological Medical Group | San Diego | California | 92103 | — |
| San Diego Urology Center | San Diego | California | 92120 | — |
| UCSF Cancer Center and Cancer Research Institute | San Francisco | California | 94115-0128 | — |
| Santa Monica Urologic Medical Group | Santa Monica | California | 90404 | — |
| Western Urological Associates | Van Nuys | California | 91405 | — |
| Urology Specialists, P.C. | Waterbury | Connecticut | 06708 | — |
| George Washington University Hospital | Washington D.C. | District of Columbia | 20037 | — |
| Atlantic Urological Associates | Daytona Beach | Florida | 32114 | — |
| University of Florida - Gainesville | Gainesville | Florida | 32610-0277 | — |
| Sylvester Cancer Center, University of Miami | Miami | Florida | 33136 | — |
| Urology Care - South | Miami | Florida | 33173 | — |
| Urology Health Center | New Port Richey | Florida | 34652 | — |
| Office of Ira W. Klimberg | Ocala | Florida | 32674 | — |
| Urology Treatment Center | Sarasota | Florida | 3429 | — |
| Georgia Urology | Atlanta | Georgia | 30342 | — |
| Affliated Urology | Chicago | Illinois | 60612 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637 | — |
| Evanston Northwestern Healthcare | Evanston | Illinois | 60201 | — |
| Clinic of Urologic Wellness | Lexington | Kentucky | 40509 | — |
| Louisiana State University Health Sciences Center - Shreveport | Shreveport | Louisiana | 71130-3932 | — |
| Cambridge Urological Associates, Inc. | Cambridge | Massachusetts | 02238 | — |
| Michigan Institute of Urology | Detroit | Michigan | 48236 | — |
| Mississippi Urology Clinic, P.A. | Jackson | Mississippi | 39202 | — |
| Urology Center | Omaha | Nebraska | 68122 | — |
| Sheldon Freedman Ltd. | Las Vegas | Nevada | 89109 | — |
| Desert Urology | North Las Vegas | Nevada | 89128 | — |
| Norris Cotton Cancer Center | Lebanon | New Hampshire | 03756 | — |
| Veterans Affairs Medical Center - East Orange | East Orange | New Jersey | 07018-1095 | — |
| Office of John Byrne | New Rochelle | New York | 10801 | — |
| Mount Sinai Medical Center, NY | New York | New York | 10029 | — |
| Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | — |
| Wake Urological Associates | Raleigh | North Carolina | 27607 | — |
| Department of Urology and Urologic Oncology | Columbus | Ohio | 43210 | — |
| Oregon Cancer Center at Oregon Health Sciences University | Portland | Oregon | 97201-3098 | — |
| Urology Clinic, P.C. | Portland | Oregon | 97210 | — |
| Office of Jeffrey K. Cohen | Pittsburgh | Pennsylvania | 15222 | — |
| Veterans Affairs Medical Center - Memphis | Memphis | Tennessee | 38104 | — |
| Vanderbilt Cancer Center | Nashville | Tennessee | 37232-6838 | — |
| Urology Associates of North Texas | Arlington | Texas | 76015 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Wilford Hall - 59th Medical Wing | Lackland Air Force Base | Texas | 78236-5300 | — |
| Veterans Affairs Medical Center - Temple | Temple | Texas | 76504 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84132 | — |
| Sentara Cancer Center | Norfolk | Virginia | 23507 | — |
| Virginia Urology Center | Richmond | Virginia | 23230 | — |
| Office of Ronald G. Anderson | Tacoma | Washington | 98405 | — |
| West Virginia University Hospitals | Morgantown | West Virginia | 26506-9162 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003725, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 6, 2013 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00003725 live on ClinicalTrials.gov.