IL-4(38-37)-PE38KDEL Immunotoxin in Treating Patients With Recurrent Malignant Astrocytoma
Public ClinicalTrials.gov record NCT00003842. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase I Study of a Recombinant Chimeric Protein Composed of Circularly Permuted IL-4 and a Mutated Form of the Pseudomonas Exotoxin Termed IL-4(38-37)-PE38KDEL (IL-4 Toxin) for the Treatment of Recurrent Malignant Astrocytoma
Study identification
- NCT ID
- NCT00003842
- Recruitment status
- Not listed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Barrett Cancer Center
- Other
- Enrollment
- 30 participants
Conditions and interventions
Conditions
Interventions
- interleukin-4 PE38KDEL cytotoxin Biological
- isolated perfusion Drug
- surgical procedure Procedure
Biological · Drug · Procedure
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 1999
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Dec 17, 2013
Started 1999
United States locations
- U.S. sites
- 10
- U.S. states
- 6
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Southern California, Healthcare Consultation Center | Los Angeles | California | 90033 | — |
| UCSF Cancer Center and Cancer Research Institute | San Francisco | California | 94115-0128 | — |
| Neuro-Oncology Service | San Francisco | California | 94143-0372 | — |
| John Wayne Cancer Institute | Santa Monica | California | 90404 | — |
| Laboratory of Molecular Biology | Bethesda | Maryland | 20892 | — |
| Food and Drug Administration | Rockville | Maryland | 20857 | — |
| St. Louis University Health Sciences Center | St Louis | Missouri | 63110-0250 | — |
| Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | — |
| Charlotte Neurosurgical Associates | Charlotte | North Carolina | 28207-1830 | — |
| Barrett Cancer Center, The University Hospital | Cincinnati | Ohio | 45219 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003842, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 17, 2013 · Synced May 13, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00003842 live on ClinicalTrials.gov.