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Terminated Phase 2 Interventional Results available

Methotrexate With or Without Cyclophosphamide in Treating Patients With Lymphocytic Leukemia

ClinicalTrials.gov ID: NCT00003910

Public ClinicalTrials.gov record NCT00003910. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 27, 2026, 1:21 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Study of Initial Treatment With Methotrexate in Large Granular Lymphocytic (LGL) Leukemia

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of methotrexate with or without cyclophosphamide in treating patients who have lymphocytic leukemia with neutropenia or anemia.

Study identification

NCT ID
NCT00003910
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Enrollment
59 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 15, 1999 (Actual)
Primary completion
Dec 1, 2010 (Actual)
Completion
Mar 2012 (Actual)
Last update posted
Jul 5, 2023

1999 – 2012

United States locations

U.S. sites
68
U.S. states
11
U.S. cities
51
Facility City State ZIP Site status
Aurora Presbyterian Hospital Aurora Colorado 80012 —
Boulder Community Hospital Boulder Colorado 80301-9019 —
Penrose Cancer Center at Penrose Hospital Colorado Springs Colorado 80933 —
St. Anthony Central Hospital Denver Colorado 80204 —
Porter Adventist Hospital Denver Colorado 80210 —
Presbyterian - St. Luke's Medical Center Denver Colorado 80218 —
St. Joseph Hospital Denver Colorado 80218 —
Rose Medical Center Denver Colorado 80220 —
CCOP - Colorado Cancer Research Program Denver Colorado 80224-2522 —
Swedish Medical Center Englewood Colorado 80110 —
St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center Grand Junction Colorado 81502 —
North Colorado Medical Center Greeley Colorado 80631 —
Sky Ridge Medical Center Lone Tree Colorado 80124 —
Hope Cancer Care Center at Longmont United Hospital Longmont Colorado 80501 —
McKee Medical Center Loveland Colorado 80539 —
St. Mary - Corwin Regional Medical Center Pueblo Colorado 81004 —
North Suburban Medical Center Thornton Colorado 80229 —
Exempla Lutheran Medical Center Wheat Ridge Colorado 80033 —
Medical Center of Central Georgia Macon Georgia 31208 —
Rush-Copley Cancer Care Center Aurora Illinois 60504 —
Robert H. Lurie Comprehensive Cancer Center at Northwestern University Chicago Illinois 60611-3013 —
Evanston Northwestern Healthcare - Evanston Hospital Evanston Illinois 60201-1781 —
Joliet Oncology-Hematology Associates, Limited - West Joliet Illinois 60435 —
North Shore Oncology and Hematology Associates, Limited - Libertyville Libertyville Illinois 60048 —
Carle Cancer Center at Carle Foundation Hospital Urbana Illinois 61801 —
CCOP - Carle Cancer Center Urbana Illinois 61801 —
Methodist Cancer Center at Methodist Hospital Indianapolis Indiana 46202 —
Saint Anthony Memorial Health Centers Michigan City Indiana 46360 —
McFarland Clinic, PC Ames Iowa 50010 —
Mercy Cancer Center at Mercy Medical Center - North Iowa Mason City Iowa 50401 —
Siouxland Hematology-Oncology Associates, LLP Sioux City Iowa 51101 —
Mercy Medical Center - Sioux City Sioux City Iowa 51104 —
St. Luke's Regional Medical Center Sioux City Iowa 51104 —
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore Maryland 21231-2410 —
Borgess Medical Center Kalamazoo Michigan 49001 —
West Michigan Cancer Center Kalamazoo Michigan 49007-3731 —
Bronson Methodist Hospital Kalamazoo Michigan 49007 —
Fairview Ridges Hospital Burnsville Minnesota 55337 —
Mercy and Unity Cancer Center at Mercy Hospital Coon Rapids Minnesota 55433 —
Fairview Southdale Hospital Edina Minnesota 55435 —
Mercy and Unity Cancer Center at Unity Hospital Fridley Minnesota 55432 —
Hutchinson Area Health Care Hutchinson Minnesota 55350 —
Meeker County Memorial Hospital Litchfield Minnesota 55355 —
HealthEast Cancer Care at St. John's Hospital Maplewood Minnesota 55109 —
Minnesota Oncology Hematology, PA - Maplewood Maplewood Minnesota 55109 —
Virginia Piper Cancer Institute at Abbott - Northwestern Hospital Minneapolis Minnesota 55407 —
Hennepin County Medical Center - Minneapolis Minneapolis Minnesota 55415 —
Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center Robbinsdale Minnesota 55422-2900 —
CCOP - Metro-Minnesota Saint Louis Park Minnesota 55416 —
Park Nicollet Cancer Center Saint Louis Park Minnesota 55416 —
Regions Hospital Cancer Care Center Saint Paul Minnesota 55101 —
HealthEast Cancer Care at St. Joseph's Hospital Saint Paul Minnesota 55102 —
United Hospital Saint Paul Minnesota 55102 —
St. Francis Cancer Center at St. Francis Medical Center Shakopee Minnesota 55379 —
Ridgeview Medical Center Waconia Minnesota 55387 —
HealthEast Cancer Care at Woodwinds Health Campus Woodbury Minnesota 55125 —
Minnesota Oncology Hematology, PA - Woodbury Woodbury Minnesota 55125 —
Aultman Cancer Center at Aultman Hospital Canton Ohio 44710-1799 —
St. Rita's Medical Center Lima Ohio 45801 —
Penn State Cancer Institute at Milton S. Hershey Medical Center Hershey Pennsylvania 17033-0850 —
Central Pennsylvania Hematology and Medical Oncology Associates, PC Lemoyne Pennsylvania 17043 —
Lewistown Hospital Lewistown Pennsylvania 17044 —
Fox Chase Cancer Center - Philadelphia Philadelphia Pennsylvania 19111-2497 —
McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center Reading Pennsylvania 19612-6052 —
Mount Nittany Medical Center State College Pennsylvania 16803 —
Gundersen Lutheran Center for Cancer and Blood La Crosse Wisconsin 54601 —
Froedtert Hospital and Medical College of Wisconsin Milwaukee Wisconsin 53226 —
Medical College of Wisconsin Cancer Center Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00003910, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 5, 2023 · Synced Oct 27, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00003910 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →