ClinicalTrials.gov record
Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu
ClinicalTrials.gov ID: NCT00004074
Public ClinicalTrials.gov record NCT00004074. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 20, 2026, 11:47 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase I Trial of Herceptin and Interleukin-12
Study identification
- NCT ID
- NCT00004074
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- National Cancer Institute (NCI)
- NIH
- Enrollment
- 15 participants
Conditions and interventions
Conditions
- Advanced Adult Primary Liver Cancer
- Anaplastic Thyroid Cancer
- Bone Metastases
- Carcinoma of the Appendix
- Distal Urethral Cancer
- Fallopian Tube Cancer
- Gastrinoma
- Glucagonoma
- Inflammatory Breast Cancer
- Insulinoma
- Liver Metastases
- Localized Unresectable Adult Primary Liver Cancer
- Lung Metastases
- Male Breast Cancer
- Malignant Pericardial Effusion
- Malignant Pleural Effusion
- Metastatic Gastrointestinal Carcinoid Tumor
- Metastatic Parathyroid Cancer
- Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter
- Newly Diagnosed Carcinoma of Unknown Primary
- Occult Non-small Cell Lung Cancer
- Pancreatic Polypeptide Tumor
- Primary Peritoneal Cavity Cancer
- Proximal Urethral Cancer
- Pulmonary Carcinoid Tumor
- Recurrent Adenoid Cystic Carcinoma of the Oral Cavity
- Recurrent Adrenocortical Carcinoma
- Recurrent Adult Primary Liver Cancer
- Recurrent Anal Cancer
- Recurrent Bladder Cancer
- Recurrent Breast Cancer
- Recurrent Carcinoma of Unknown Primary
- Recurrent Cervical Cancer
- Recurrent Colon Cancer
- Recurrent Endometrial Carcinoma
- Recurrent Esophageal Cancer
- Recurrent Extrahepatic Bile Duct Cancer
- Recurrent Gallbladder Cancer
- Recurrent Gastric Cancer
- Recurrent Gastrointestinal Carcinoid Tumor
- Recurrent Islet Cell Carcinoma
- Recurrent Malignant Testicular Germ Cell Tumor
- Recurrent Mucoepidermoid Carcinoma of the Oral Cavity
- Recurrent Non-small Cell Lung Cancer
- Recurrent Ovarian Epithelial Cancer
- Recurrent Pancreatic Cancer
- Recurrent Parathyroid Cancer
- Recurrent Prostate Cancer
- Recurrent Rectal Cancer
- Recurrent Renal Cell Cancer
- Recurrent Salivary Gland Cancer
- Recurrent Small Intestine Cancer
- Recurrent Squamous Cell Carcinoma of the Larynx
- Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity
- Recurrent Squamous Cell Carcinoma of the Nasopharynx
- Recurrent Squamous Cell Carcinoma of the Oropharynx
- Recurrent Thyroid Cancer
- Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter
- Recurrent Urethral Cancer
- Recurrent Vaginal Cancer
- Recurrent Vulvar Cancer
- Skin Metastases
- Small Intestine Adenocarcinoma
- Somatostatinoma
- Stage III Adenoid Cystic Carcinoma of the Oral Cavity
- Stage III Adrenocortical Carcinoma
- Stage III Bladder Cancer
- Stage III Cervical Cancer
- Stage III Colon Cancer
- Stage III Endometrial Carcinoma
- Stage III Esophageal Cancer
- Stage III Follicular Thyroid Cancer
- Stage III Gastric Cancer
- Stage III Malignant Testicular Germ Cell Tumor
- Stage III Mucoepidermoid Carcinoma of the Oral Cavity
- Stage III Ovarian Epithelial Cancer
- Stage III Pancreatic Cancer
- Stage III Papillary Thyroid Cancer
- Stage III Prostate Cancer
- Stage III Rectal Cancer
- Stage III Renal Cell Cancer
- Stage III Salivary Gland Cancer
- Stage III Squamous Cell Carcinoma of the Larynx
- Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity
- Stage III Squamous Cell Carcinoma of the Nasopharynx
- Stage III Squamous Cell Carcinoma of the Oropharynx
- Stage III Vaginal Cancer
- Stage III Vulvar Cancer
- Stage IIIA Anal Cancer
- Stage IIIA Breast Cancer
- Stage IIIA Non-small Cell Lung Cancer
- Stage IIIB Anal Cancer
- Stage IIIB Breast Cancer
- Stage IIIB Non-small Cell Lung Cancer
- Stage IV Adenoid Cystic Carcinoma of the Oral Cavity
- Stage IV Adrenocortical Carcinoma
- Stage IV Anal Cancer
- Stage IV Bladder Cancer
- Stage IV Breast Cancer
- Stage IV Colon Cancer
- Stage IV Endometrial Carcinoma
- Stage IV Esophageal Cancer
- Stage IV Follicular Thyroid Cancer
- Stage IV Gastric Cancer
- Stage IV Mucoepidermoid Carcinoma of the Oral Cavity
- Stage IV Non-small Cell Lung Cancer
- Stage IV Ovarian Epithelial Cancer
- Stage IV Pancreatic Cancer
- Stage IV Papillary Thyroid Cancer
- Stage IV Prostate Cancer
- Stage IV Rectal Cancer
- Stage IV Renal Cell Cancer
- Stage IV Salivary Gland Cancer
- Stage IV Squamous Cell Carcinoma of the Larynx
- Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity
- Stage IV Squamous Cell Carcinoma of the Nasopharynx
- Stage IV Squamous Cell Carcinoma of the Oropharynx
- Stage IVA Cervical Cancer
- Stage IVA Vaginal Cancer
- Stage IVB Cervical Cancer
- Stage IVB Vaginal Cancer
- Stage IVB Vulvar Cancer
- Thyroid Gland Medullary Carcinoma
- Unresectable Extrahepatic Bile Duct Cancer
- Unresectable Gallbladder Cancer
- Urethral Cancer Associated With Invasive Bladder Cancer
- WDHA Syndrome
Interventions
- ABI-007/carboplatin/trastuzumab Biological
- recombinant interleukin-12 Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 31, 1999
- Primary completion
- Jan 31, 2009
- Completion
- Not listed
- Last update posted
- Feb 27, 2013
Started 1999
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Ohio State University Medical Center | Columbus | Ohio | 43210 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00004074, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 27, 2013 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00004074 live on ClinicalTrials.gov.