Comparison of Three Treatment Regimens in Treating Patients With Relapsed or Refractory Acute Myelogenous Leukemia
Public ClinicalTrials.gov record NCT00005962. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Randomized Trial of Immunologic and Chemotherapeutic Agents for Treatment of Patients With Relapsed or Refractory Acute Myelogenous Leukemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies such as gemtuzumab ozogamicin can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining more than one drug or combining monoclonal antibody with chemotherapy may kill more cancer cells. It is not yet known which treatment regimen is more effective for acute myelogenous leukemia. PURPOSE: Randomized phase II trial to compare the effectiveness of three treatment regimens in treating patients who have relapsed or refractory acute myelogenous leukemia.
Study identification
- NCT ID
- NCT00005962
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- Not listed
Conditions and interventions
Conditions
Interventions
- sargramostim Biological
- cyclophosphamide Drug
- cytarabine Drug
- gemtuzumab ozogamicin Drug
- liposomal daunorubicin citrate Drug
- topotecan hydrochloride Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- 18 Years to 120 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 4, 2000 (Actual)
- Primary completion
- Oct 2005 (Actual)
- Completion
- Jun 2007 (Actual)
- Last update posted
- Jun 22, 2023
2000 – 2007
United States locations
- U.S. sites
- 62
- U.S. states
- 23
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| CCOP - Scottsdale Oncology Program | Scottsdale | Arizona | 85259-5404 | — |
| Cancer Center and Beckman Research Institute, City of Hope | Duarte | California | 91010-3000 | — |
| Veterans Affairs Medical Center - Palo Alto | Palo Alto | California | 94304 | — |
| Stanford University Medical Center | Stanford | California | 94305-5408 | — |
| CCOP - Colorado Cancer Research Program, Inc. | Denver | Colorado | 80209-5031 | — |
| CCOP - Christiana Care Health Services | Wilmington | Delaware | 19899 | — |
| Veterans Affairs Medical Center - Gainsville | Gainesville | Florida | 32608-1197 | — |
| Veterans Affairs Medical Center - Miami | Miami | Florida | 33125 | — |
| H. Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612-9497 | — |
| Veterans Affairs Medical Center - Tampa (Haley) | Tampa | Florida | 33612 | — |
| Robert H. Lurie Comprehensive Cancer Center, Northwestern University | Chicago | Illinois | 60611-3013 | — |
| Veterans Affairs Medical Center - Lakeside Chicago | Chicago | Illinois | 60611 | — |
| CCOP - Central Illinois | Decatur | Illinois | 62526 | — |
| CCOP - Evanston | Evanston | Illinois | 60201 | — |
| CCOP - Illinois Oncology Research Association | Peoria | Illinois | 61602 | — |
| CCOP - Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Indiana University Cancer Center | Indianapolis | Indiana | 46202-5289 | — |
| Veterans Affairs Medical Center - Indianapolis (Roudebush) | Indianapolis | Indiana | 46202 | — |
| CCOP - Cedar Rapids Oncology Project | Cedar Rapids | Iowa | 52403-1206 | — |
| CCOP - Iowa Oncology Research Association | Des Moines | Iowa | 50309-1016 | — |
| Holden Comprehensive Cancer Center at The University of Iowa | Iowa City | Iowa | 52242-1009 | — |
| MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| CCOP - Ochsner | New Orleans | Louisiana | 70121 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21231-2410 | — |
| New England Medical Center Hospital | Boston | Massachusetts | 02111 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| CCOP - Ann Arbor Regional | Ann Arbor | Michigan | 48106 | — |
| CCOP - Kalamazoo | Kalamazoo | Michigan | 49007-3731 | — |
| CCOP - Duluth | Duluth | Minnesota | 55805 | — |
| Veterans Affairs Medical Center - Minneapolis | Minneapolis | Minnesota | 55417 | — |
| University of Minnesota Cancer Center | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | — |
| CCOP - Metro-Minnesota | Saint Louis Park | Minnesota | 55416 | — |
| Veterans Affairs Medical Center - Omaha | Omaha | Nebraska | 68105 | — |
| CCOP - Missouri Valley Cancer Consortium | Omaha | Nebraska | 68131 | — |
| CCOP - Southern Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| Veterans Affairs Medical Center - East Orange | East Orange | New Jersey | 07018-1095 | — |
| CCOP - Northern New Jersey | Hackensack | New Jersey | 07601 | — |
| Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | — |
| Veterans Affairs Medical Center - Brooklyn | Brooklyn | New York | 11209 | — |
| Veterans Affairs Medical Center - New York | New York | New York | 10010 | — |
| NYU School of Medicine's Kaplan Comprehensive Cancer Center | New York | New York | 10016 | — |
| University of Rochester Cancer Center | Rochester | New York | 14642 | — |
| Albert Einstein Comprehensive Cancer Center | The Bronx | New York | 10461 | — |
| MBCCOP-Our Lady of Mercy Cancer Center | The Bronx | New York | 10466 | — |
| CCOP - Merit Care Hospital | Fargo | North Dakota | 58122 | — |
| Ireland Cancer Center | Cleveland | Ohio | 44106-5065 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| CCOP - Columbus | Columbus | Ohio | 43206 | — |
| CCOP - Toledo Community Hospital Oncology Program | Toledo | Ohio | 43623-3456 | — |
| CCOP - Oklahoma | Tulsa | Oklahoma | 74136 | — |
| Hahnemann University Hospital | Philadelphia | Pennsylvania | 19102-1192 | — |
| University of Pennsylvania Cancer Center | Philadelphia | Pennsylvania | 19104-4283 | — |
| Kimmel Cancer Center of Thomas Jefferson University - Philadelphia | Philadelphia | Pennsylvania | 19107-5541 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | 15213-3489 | — |
| Veterans Affairs Medical Center - Pittsburgh | Pittsburgh | Pennsylvania | 15240 | — |
| CCOP - MainLine Health | Wynnewood | Pennsylvania | 19096 | — |
| CCOP - Sioux Community Cancer Consortium | Sioux Falls | South Dakota | 57104 | — |
| Veterans Affairs Medical Center - Madison | Madison | Wisconsin | 53705 | — |
| University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | 53792-6164 | — |
| CCOP - Marshfield Medical Research and Education Foundation | Marshfield | Wisconsin | 54449 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00005962, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 22, 2023 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00005962 live on ClinicalTrials.gov.