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Completed Phase 2 Interventional

Temozolomide Plus Thalidomide in Treating Patients With Recurrent or Progressive Brain Tumor

ClinicalTrials.gov ID: NCT00006358

Public ClinicalTrials.gov record NCT00006358. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 31, 2026, 7:58 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase II Evaluation of Temozolomide (SCH52365) and Thalidomide for the Treatment of Recurrent and Progressive Glioblastoma Multiforme

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Thalidomide may stop the growth of cancer by stopping blood flow to the tumor. PURPOSE: Phase II trial to study the effectiveness of combining temozolomide and thalidomide in treating patients who have recurrent or progressive brain tumor.

Study identification

NCT ID
NCT00006358
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
44 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 120 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 13, 2000 (Actual)
Primary completion
Jan 23, 2003 (Actual)
Completion
Jul 20, 2006 (Actual)
Last update posted
Jun 26, 2018

2000 – 2006

United States locations

U.S. sites
11
U.S. states
8
U.S. cities
11
Facility City State ZIP Site status
Jonsson Comprehensive Cancer Center, UCLA Los Angeles California 90095-1781 —
UCSF Cancer Center and Cancer Research Institute San Francisco California 94115-0128 —
Neuro-Oncology Branch Bethesda Maryland 20892 —
Dana-Farber Cancer Institute Boston Massachusetts 02115 —
University of Michigan Comprehensive Cancer Center Ann Arbor Michigan 48109-0752 —
Memorial Sloan-Kettering Cancer Center New York New York 10021 —
University of Pittsburgh Cancer Institute Pittsburgh Pennsylvania 15213 —
Simmons Cancer Center - Dallas Dallas Texas 75235-9154 —
University of Texas - MD Anderson Cancer Center Houston Texas 77030 —
University of Texas Health Science Center at San Antonio San Antonio Texas 78284-7811 —
University of Wisconsin Comprehensive Cancer Center Madison Wisconsin 53792 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00006358, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 26, 2018 · Synced Oct 31, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00006358 live on ClinicalTrials.gov.

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