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Completed Phase 3 Interventional Accepts healthy volunteers

Antibiotic Treatment of Gulf War Veterans' Illnesses

ClinicalTrials.gov ID: NCT00007735

Public ClinicalTrials.gov record NCT00007735. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 5, 2026, 11:53 AM EST

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Official title

CSP #475 - Persian Gulf - Antibiotic Treatment Trial of Gulf War Veterans' Illnesses

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

In 1990 and 1991, the U.S. deployed approximately 700,000 troops to the Persian Gulf to liberate Kuwait from Iraqi occupation. While there were few casualties associated with the Gulf War, many individuals returned from this conflict with unexplained symptoms and illnesses. This constellation of symptoms has been termed Gulf War Veterans' Illnesses (GWI). Although several explanations have been offered as to the cause of GWI, none of the putative etiologic agents or conditions is currently supported by sufficient evidence. One explanation that has received fairly widespread attention is systemic Mycoplasma fermentans infection. It is the purpose of this study to determine if antibiotic treatment directed against Mycoplasma species (i.e. doxycycline) will improve functioning and symptoms in deployed Gulf War veterans with GWI.

Study identification

NCT ID
NCT00007735
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Enrollment
450 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 1999 (Type not available)
Primary completion
Not listed
Completion
Oct 2001 (Type not available)
Last update posted
Oct 30, 2023

1999 – 2001

United States locations

U.S. sites
26
U.S. states
24
U.S. cities
26
Facility City State ZIP Site status
Vamc - Birmingham, Al Birmingham Alabama 35233 —
Naval Health Research Center Merchant Illness Divi San Diego California 92152 —
Uniformed Services University Department of Psychi Washington D.C. District of Columbia 20307-5001 —
Vamc - Augusta, Ga Augusta Georgia 30904-6285 —
Vamc - Hines,Il Hines Illinois 60141 —
Vamc - New Orleans, La New Orleans Louisiana 70146 —
Vamc - Boston, Ma Boston Massachusetts 02130 —
Vamc - Omaha, NE Omaha Nebraska 68105 —
Vamc - Manchester,Nh Manchester New Hampshire 03103 —
Vamc - East Orange, Nj East Orange New Jersey 07018 —
Vamc - Albuquerque, Nm Albuquerque New Mexico 87108 —
Vamc - Albany, Ny Albany New York 12208 —
Vamc - Brooklyn, Ny Brooklyn New York 11209 —
Vamc - Bronx,Ny The Bronx New York 10468 —
Vamc - Durham, Nc Durham North Carolina 27705 —
Vamc - Fargo, Nd Fargo North Dakota 58102-2498 —
Vamc - Dayton, Oh Kettering Ohio 45429 —
Vamc - Oklahoma City, Ok Oklahoma City Oklahoma 73104 —
Vamc - Philadelphia, Pa Philadelphia Pennsylvania 19104 —
Vamc - Providence, Ri Providence Rhode Island 02908-4799 —
Vamc - Charleston, Sc Charleston South Carolina 29401-5799 —
Vamc - Nashville, Tn Nashville Tennessee 37212-2637 —
Vamc - Houston, Tx Houston Texas 77030-4298 —
Vamc - White River Junction White River Junction Vermont 05009 —
Vamc - Richmond, Va Richmond Virginia 23249 —
Vamc - Milwaukee, Wi Milwaukee Wisconsin 53295 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00007735, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 30, 2023 · Synced Nov 5, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00007735 live on ClinicalTrials.gov.

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