Radiation Therapy and Chemotherapy Followed by Surgery and Combination Chemotherapy in Treating Patients With Rectal Cancer
Public ClinicalTrials.gov record NCT00021398. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase II Study: Hyperfractionated Pre-Op Chemo-Radiation for Locally Advanced Rectal Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy and chemotherapy may shrink the tumor so that it can be removed during surgery. PURPOSE: Phase II trial to study the effectiveness of radiation therapy and chemotherapy followed by surgery and combination chemotherapy in treating patients who have stage II or stage III rectal cancer.
Study identification
- NCT ID
- NCT00021398
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 23 participants
Conditions and interventions
Conditions
Interventions
- fluorouracil Drug
- leucovorin calcium Drug
- conventional surgery Procedure
- radiation therapy Radiation
Drug · Procedure · Radiation
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 1996 (Type not available)
- Primary completion
- Jul 2001 (Actual)
- Completion
- Sep 2018 (Actual)
- Last update posted
- Jun 5, 2020
1996 – 2018
United States locations
- U.S. sites
- 17
- U.S. states
- 2
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Hunterdon Regional Cancer Center | Flemington | New Jersey | 08822 | — |
| Kimball Medical Center | Lakewood | New Jersey | 08701 | — |
| Fox Chase Cancer Center at Virtua Memorial Hospital Burlington County | Mount Holly | New Jersey | 08060 | — |
| Riverview Medical Center | Red Bank | New Jersey | 07701 | — |
| Community Medical Center | Toms River | New Jersey | 08755 | — |
| St. Francis Medical Center | Trenton | New Jersey | 08629 | — |
| Bon Secours-Holy Family Health System | Altoona | Pennsylvania | 16602 | — |
| Delaware County Memorial Hospital | Drexel Hill | Pennsylvania | 19026 | — |
| Pinnacle Health Hospitals | Harrisburg | Pennsylvania | 17105-8700 | — |
| Conemaugh Memorial Hospital | Johnstown | Pennsylvania | 15905 | — |
| Saint Mary Regional Center | Langhorne | Pennsylvania | 19047 | — |
| North Penn Hospital | Lansdale | Pennsylvania | 19446 | — |
| Paoli Memorial Hospital | Paoli | Pennsylvania | 19301-1792 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Pottstown Memorial Regional Cancer Center | Pottstown | Pennsylvania | 19464 | — |
| Reading Hospital and Medical Center | Reading | Pennsylvania | 19612-6052 | — |
| Southern Chester County Medical Center | West Grove | Pennsylvania | 19390 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00021398, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 5, 2020 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00021398 live on ClinicalTrials.gov.