Combination Chemotherapy With or Without Donor Bone Marrow Transplantation in Treating Infants With Previously Untreated Acute Lymphoblastic Leukemia
Public ClinicalTrials.gov record NCT00022126. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Study of Modified Augmented BFM Therapy for Infants With Acute Lymphoblastic Leukemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Giving the drugs in different combinations may kill more cancer cells. Bone marrow transplantation allows the doctor to give higher doses of chemotherapy and kill more cancer cells. PURPOSE: Phase II trial to compare the effectiveness of combination chemotherapy with or without donor bone marrow transplantation in treating infants who have previously untreated acute lymphoblastic leukemia.
Study identification
- NCT ID
- NCT00022126
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 6 participants
Conditions and interventions
Conditions
Interventions
- asparaginase Drug
- cyclophosphamide Drug
- cyclosporine Drug
- cytarabine Drug
- daunorubicin hydrochloride Drug
- dexamethasone Drug
- doxorubicin hydrochloride Drug
- mercaptopurine Drug
- methotrexate Drug
- methylprednisolone Drug
- pegaspargase Drug
- thioguanine Drug
- vincristine sulfate Drug
- allogeneic bone marrow transplantation Procedure
- radiation therapy Radiation
Drug · Procedure · Radiation
Eligibility (public fields only)
- Age range
- Up to 1 Year
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2002 (Type not available)
- Primary completion
- Jan 2005 (Actual)
- Completion
- Apr 2006 (Actual)
- Last update posted
- Feb 20, 2014
2002 – 2006
United States locations
- U.S. sites
- 47
- U.S. states
- 24
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Children's Hospital | Phoenix | Arizona | 85016 | — |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| Children's Hospital Los Angeles | Los Angeles | California | 90027-0700 | — |
| Jonsson Comprehensive Cancer Center, UCLA | Los Angeles | California | 90095-1781 | — |
| Children's Hospital Central California | Madera | California | 93638-8762 | — |
| Children's Hospital of Oakland | Oakland | California | 94609-1809 | — |
| Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center | Orange | California | 92868 | — |
| Children's Hospital of Orange County | Orange | California | 92868 | — |
| Children's Hospital of Denver | Denver | Colorado | 80218-1088 | — |
| University of Connecticut Health Center | Farmington | Connecticut | 06360-7106 | — |
| Alfred I. duPont Hospital for Children | Wilmington | Delaware | 19899 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010-2970 | — |
| Emory University Hospital - Atlanta | Atlanta | Georgia | 30322 | — |
| Children's Healthcare of Atlanta - Scottish Rite | Atlanta | Georgia | 30342 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60601 | — |
| Indiana University Cancer Center | Indianapolis | Indiana | 46202-5289 | — |
| John Stoddard Cancer Center at Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | — |
| Holden Comprehensive Cancer Center at University of Iowa | Iowa City | Iowa | 52242-1009 | — |
| MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0914 | — |
| Children's Hospitals and Clinics - Minneapolis | Minneapolis | Minnesota | 55404 | — |
| Children's Hospitals and Clinics - Minnesota | Saint Paul | Minnesota | 55102 | — |
| Children's Mercy Hospital | Kansas City | Missouri | 64108 | — |
| Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| Mount Sinai School of Medicine | New York | New York | 10029 | — |
| Herbert Irving Comprehensive Cancer Center at Columbia University | New York | New York | 10032 | — |
| Lineberger Comprehensive Cancer Center, UNC | Chapel Hill | North Carolina | 27599-7295 | — |
| Children's Hospital Medical Center of Akron | Akron | Ohio | 44308 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229-3039 | — |
| Children's Hospital of Columbus | Columbus | Ohio | 43205-2696 | — |
| Children's Medical Center - Dayton | Dayton | Ohio | 45404 | — |
| Doernbecher Children's Hospital | Portland | Oregon | 97201-3098 | — |
| CCOP - Columbia River Oncology Program | Portland | Oregon | 97225 | — |
| Penn State Cancer Institute at Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| University of Texas - MD Anderson Cancer Center | Houston | Texas | 77030-4009 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Methodist Cancer Center | San Antonio | Texas | 78229-3902 | — |
| CCOP - Scott and White Hospital | Temple | Texas | 76508 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | — |
| Children's Hospital and Regional Medical Center - Seattle | Seattle | Washington | 98105 | — |
| Deaconess Medical Center | Spokane | Washington | 99210-0248 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431-5000 | — |
| CCOP - St. Vincent Hospital Cancer Center, Green Bay | Green Bay | Wisconsin | 54301 | — |
| University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | 53792-6164 | — |
| CCOP - Marshfield Clinic Research Foundation | Marshfield | Wisconsin | 54449 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00022126, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 20, 2014 · Synced Nov 1, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00022126 live on ClinicalTrials.gov.