Radiation Therapy Plus Celecoxib, Fluorouracil, and Cisplatin in Patients With Locally Advanced Cervical Cancer
Public ClinicalTrials.gov record NCT00023660. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Phase I/II Study Of COX-2 Inhibitor, CELEBREX (CELECOXIB), And Chemoradiation In Patients With Locally Advanced Cervical Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving radiation therapy in different ways and combining it with chemotherapy may kill more tumor cells. Celecoxib may slow the growth of cervical cancer by stopping blood flow to the tumor. PURPOSE: Phase I/II trial to study the effectiveness of radiation therapy plus celecoxib, fluorouracil, and cisplatin in treating patients who have locally advanced cervical cancer.
Study identification
- NCT ID
- NCT00023660
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 84 participants
Conditions and interventions
Conditions
Interventions
- celecoxib Drug
- cisplatin Drug
- fluorouracil Drug
- brachytherapy Radiation
- radiation therapy Radiation
Drug · Radiation
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2001 (Type not available)
- Primary completion
- Jan 2005 (Actual)
- Completion
- Not listed
- Last update posted
- Nov 19, 2013
Started 2001
United States locations
- U.S. sites
- 36
- U.S. states
- 20
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mobile Infirmary Medical Center | Mobile | Alabama | 36652-2144 | — |
| Foundation for Cancer Research and Education | Phoenix | Arizona | 85013 | — |
| Mills-Peninsula Health Services | Burlingame | California | 94010 | — |
| Sutter Health Western Division Cancer Research Group | Greenbrae | California | 94904 | — |
| UCSF Comprehensive Cancer Center | San Francisco | California | 94143-0128 | — |
| Memorial Hospital Cancer Center | Colorado Springs | Colorado | 80909 | — |
| Baptist Hospital of Miami | Miami | Florida | 33256-2110 | — |
| Regional Radiation Oncology Center at Rome | Rome | Georgia | 30165 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | — |
| Ball Memorial Hospital Cancer Center | Muncie | Indiana | 47303-3499 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| Methodist Hospital Cancer Center at Nebraska Methodist Hospital - Omaha | Omaha | Nebraska | 68114-4199 | — |
| CCOP - Southern Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| Monmouth Medical Center | Long Branch | New Jersey | 07740-6395 | — |
| South Jersey Regional Cancer Center | Millville | New Jersey | 08332 | — |
| Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital | Mount Holly | New Jersey | 08060 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| Community Medical Center | Toms River | New Jersey | 08755 | — |
| State University of New York Health Science Center at Brooklyn | Brooklyn | New York | 11203 | — |
| New York Methodist Hospital | Brooklyn | New York | 11215 | — |
| Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | 27157-1065 | — |
| Akron General Medical Center | Akron | Ohio | 44302 | — |
| Akron City Hospital - Summa Health System | Akron | Ohio | 44304 | — |
| Bryn Mawr Hospital | Bryn Mawr | Pennsylvania | 19010 | — |
| Mercy Fitzgerald Hospital | Darby | Pennsylvania | 19023 | — |
| Delaware County Memorial Hospital | Drexel Hill | Pennsylvania | 19026 | — |
| Paoli Memorial Hospital | Paoli | Pennsylvania | 19301-1792 | — |
| Kimmel Cancer Center at Thomas Jefferson University - Philadelphia | Philadelphia | Pennsylvania | 19107-5097 | — |
| Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| CCOP - MainLine Health | Wynnewood | Pennsylvania | 19096 | — |
| Lankenau Cancer Center at Lankenau Hospital | Wynnewood | Pennsylvania | 19096 | — |
| University of Texas - MD Anderson Cancer Center | Houston | Texas | 77030-4009 | — |
| LDS Hospital | Salt Lake City | Utah | 84143 | — |
| Dixie Regional Medical Center | St. George | Utah | 84770 | — |
| CCOP - Marshfield Clinic Research Foundation | Marshfield | Wisconsin | 54449 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00023660, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 19, 2013 · Synced Nov 10, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00023660 live on ClinicalTrials.gov.