Gemcitabine With or Without Exatecan Mesylate in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Public ClinicalTrials.gov record NCT00023972. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Open-Label, Multicenter Phase III Study Comparing the Efficacy and Safety of a Combination of Intravenous DX-8951f (Exatecan Mesylate) Plus Gemcitabine to Gemcitabine Alone in Patients With Locally Advanced or Metastatic Cancer of the Exocrine Pancreas Who Have Not Received Prior Chemotherapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if gemcitabine is more effective with or without exatecan mesylate in treating pancreatic cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of gemcitabine alone to that of gemcitabine and exatecan mesylate in treating patients who have locally advanced or metastatic pancreatic cancer.
Study identification
- NCT ID
- NCT00023972
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- Not listed
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2001
- Primary completion
- Mar 31, 2005
- Completion
- Mar 31, 2005
- Last update posted
- May 15, 2012
2001 – 2005
United States locations
- U.S. sites
- 66
- U.S. states
- 27
- U.S. cities
- 62
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Intouch Research | Huntsville | Alabama | 35801 | — |
| Providence Cancer Center | Mobile | Alabama | 36608 | — |
| Arizona Clinical Research Center | Tucson | Arizona | 85712 | — |
| Medical Oncology/Hematology | Gilroy | California | 95020 | — |
| California Cancer Care, Inc. | Greenbrae | California | 94904-2007 | — |
| Pacific Shores Medical Group | Long Beach | California | 90813 | — |
| Cancer and Blood Institute of the Desert | Rancho Mirage | California | 92270 | — |
| Sutter Cancer Center | Sacramento | California | 95816 | — |
| University of Colorado Cancer Center | Denver | Colorado | 80010 | — |
| Medical Oncology and Hematology, P.C. | Hamden | Connecticut | 06518 | — |
| nTouch Research | Melbourne | Florida | 32901 | — |
| Sylvester Cancer Center, University of Miami | Miami | Florida | 33136 | — |
| MD Anderson Cancer Center Orlando | Orlando | Florida | 32806 | — |
| H. Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612 | — |
| Peachtree Hematology and Oncology Consultants, P.C. | Atlanta | Georgia | 30309 | — |
| Emory University School of Medicine | Atlanta | Georgia | 30322 | — |
| Central Georgia Hematology Oncology, P.C. | Macon | Georgia | 31201 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813-2424 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611-5933 | — |
| Lutheran General Cancer Care Center | Park Ridge | Illinois | 60068 | — |
| Hope Center | Terre Haute | Indiana | 47802 | — |
| Harbor Hospital Center | Baltimore | Maryland | 21215-1290 | — |
| Oncology-Hematology Associates, P.A. | Clinton | Maryland | 20735 | — |
| Providence Hospital Cancer Center | Southfield | Michigan | 48075 | — |
| Virginia Piper Cancer Institute | Minneapolis | Minnesota | 55407 | — |
| St. Joseph Oncology, Inc. | Saint Joseph | Missouri | 64507 | — |
| St. Louis University Health Sciences Center | St Louis | Missouri | 63110-0250 | — |
| Midwest Hematology Oncology Consultants, Ltd. | St Louis | Missouri | 63136 | — |
| Billings Oncology Associates | Billings | Montana | 59101 | — |
| Great Falls Clinic | Great Falls | Montana | 59405 | — |
| Nevada Cancer Center | Las Vegas | Nevada | 89109 | — |
| Center for Cancer And Hematologic Disease | Cherry Hill | New Jersey | 08046 | — |
| Hematology Oncology Associates | Morristown | New Jersey | 07962 | — |
| Hematology and Oncology Group | Somerset | New Jersey | 08873 | — |
| Summit Medical Group, P.A. | Summit | New Jersey | 07901 | — |
| HemOnCare, P.C. | Brooklyn | New York | 11235 | — |
| Mary Imogene Bassett Hospital | Cooperstown | New York | 13326 | — |
| Nassau Hematology/Oncology PC | Lake Success | New York | 11042 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | — |
| State University of New York Health Sciences Center - Stony Brook | Stony Brook | New York | 11794-8174 | — |
| New York Medical College | Valhalla | New York | 10595 | — |
| Buffalo Medical Group, P.C. | Williamsville | New York | 14221 | — |
| Lineberger Comprehensive Cancer Center, UNC | Chapel Hill | North Carolina | 27599-7295 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| N.W. Carolina Oncology & Hematology, P.A. | Hickory | North Carolina | 28602 | — |
| Ireland Cancer Center | Cleveland | Ohio | 44106-1714 | — |
| Cleveland Clinic Cancer Center | Cleveland | Ohio | 44111 | — |
| Mid-Ohio Oncology/Hematology, Inc. | Columbus | Ohio | 43222 | — |
| Medical Oncology Associates of Wyoming Valley, P.C. | Kingston | Pennsylvania | 18704-5527 | — |
| Lancaster Cancer Center | Lancaster | Pennsylvania | 17604 | — |
| University of Pennsylvania Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| Lifespan: The Miriam Hospital | Providence | Rhode Island | 02906 | — |
| Memorial Hospital Cancer Center - Chattanooga | Chattanooga | Tennessee | 37404 | — |
| Williamson Medical Center | Franklin | Tennessee | 37067 | — |
| Family Cancer Center | Germantown | Tennessee | 38138 | — |
| Jackson-Madison County General Hospital | Jackson | Tennessee | 38301 | — |
| Sarah Cannon-Minnie Pearl Cancer Center | Nashville | Tennessee | 37203 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232-6307 | — |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410-1894 | — |
| Cancer Therapy and Research Center | San Antonio | Texas | 78229-3271 | — |
| Scott and White Memorial Hospital | Temple | Texas | 76502 | — |
| Central Utah Medical Clinic | Provo | Utah | 84604 | — |
| Intermountain Hematology/Oncology Associates, Inc. | Salt Lake City | Utah | 84124-1363 | — |
| Rainier Oncology | Puyallup | Washington | 98372 | — |
| Yakima Regional Cancer Care Center | Yakima | Washington | 98902 | — |
| UW Cancer Center Wausau Hospital | Wausau | Wisconsin | 54401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00023972, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 15, 2012 · Synced Sep 25, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00023972 live on ClinicalTrials.gov.