Safety & Efficacy of Omeprazole Sodium Bicarbonate for the Prevention of Upper GI Bleeding in the Critically Ill
Public ClinicalTrials.gov record NCT00045799. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Critically ill patients are at an increased risk of having upper gastrointestinal (GI) bleeding due to stress related mucosal damage. Cimetidine, delivered continuously through intravenous infusion, is the only drug that the FDA has approved for the prevention of upper GI bleeding in critically ill patients. The present trial is intended to assess the safety and efficacy of an omeprazole sodium bicarbonate immediate-release suspension in this indication.
Study identification
- NCT ID
- NCT00045799
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 354 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 16 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2002 (Type not available)
- Primary completion
- Not listed
- Completion
- May 2003 (Actual)
- Last update posted
- Nov 25, 2019
2002 – 2003
United States locations
- U.S. sites
- 58
- U.S. states
- 27
- U.S. cities
- 52
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| University of South Alabama | Mobile | Alabama | 36617 | — |
| Arizona Pulmonary Specialists | Phoenix | Arizona | 85006 | — |
| Maricopa Medical Center | Phoenix | Arizona | 85008 | — |
| Arizona Pulmonary Specialists, Ltd | Phoenix | Arizona | 85013 | — |
| Scottsdale Healthcare | Scottsdale | Arizona | 85258 | — |
| Alta Bates Summit Medical Center | Berkeley | California | 94705 | — |
| Providence St. Joseph's Medical Center | Burbank | California | 91505 | — |
| Verdugo Hills Hospital | Burbank | California | 91505 | — |
| Loma Linda Medical Center | Loma Linda | California | 92354 | — |
| Stanford University School of Medicine | Stanford | California | 94305 | — |
| Christiana Hospital | Newark | Delaware | 19718 | — |
| PAB Clinical Research | Brandon | Florida | 33511 | — |
| Shands Hospital at the University of Florida | Gainesville | Florida | 32610 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| Miami VAMC | Miami | Florida | 33125 | — |
| Jackson Memorial Hospital | Miami | Florida | 33136 | — |
| USF Pulmonary Research | Tampa | Florida | 33606 | — |
| Protocare Trials | Austell | Georgia | 30106 | — |
| Wellstar Kennestone Hospital | Marietta | Georgia | 30060 | — |
| Protocare - Alexian Brothers Center for Clinical Research | Elk Grove Village | Illinois | 60007 | — |
| West Suburban Hospital | Oak Park | Illinois | 60302 | — |
| University of Iowa Health Care | Iowa City | Iowa | 52242 | — |
| Department of Medicine | Kansas City | Kansas | 66160 | — |
| Medical Center of LA at New Orleans (LSU Health Sci Ctr) | New Orleans | Louisiana | 70112 | — |
| Louisiana State University | Shreveport | Louisiana | 71130 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| University of Massachusetts | Worcester | Massachusetts | 01655 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55414 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| Truman Medical Center Hospital Hill | Kansas City | Missouri | 64108 | — |
| St. Johns Hospital | Springfield | Missouri | 65804 | — |
| Washington University School of Medicine | St Louis | Missouri | 63109 | — |
| University of Nebraska | Omaha | Nebraska | 68198 | — |
| Cooper Hospital/UMC | Camden | New Jersey | 08103 | — |
| Trinitas Hospital | Elizabeth | New Jersey | 07207 | — |
| Morristown Memorial Hospital | Morristown | New Jersey | 07960 | — |
| University Hospital | Newark | New Jersey | 07103 | — |
| SUNY Health Science Center | Brooklyn | New York | 11203 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| Long Island Jewish Medical Center | New Hyde Park | New York | 11040 | — |
| St. Vincent's Catholic Medical Center | New York | New York | 10011 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Akron General Hospital | Akron | Ohio | 44307 | — |
| The Toledo Hospital | Toledo | Ohio | 43606 | — |
| Oregon Health & Science University | Portland | Oregon | 97201 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| University of Tennessee | Memphis | Tennessee | 38163 | — |
| Vanderbilt University | Nashville | Tennessee | 37212 | — |
| North Texas Affiliated Medical Group | Fort Worth | Texas | 76104 | — |
| Texas Tech University Health Sciences Center | Odessa | Texas | 79763 | — |
| University of Vermont | Burlington | Vermont | 05401 | — |
| Pulmonary & Critical Care | Richmond | Virginia | 23249 | — |
| West Virginia University Hospitals, Inc | Morgantown | West Virginia | 26506 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00045799, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 25, 2019 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00045799 live on ClinicalTrials.gov.