ClinicalTrials.gov record
Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure.
ClinicalTrials.gov ID: NCT00048425
Public ClinicalTrials.gov record NCT00048425. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 12, 2026, 7:20 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Multicenter Evaluation of Intravenous Levosimendan Efficacy Versus Placebo in the Short Term Treatment of Decompensated Chronic Heart Failure: the REVIVE II Study.
Study identification
- NCT ID
- NCT00048425
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Abbott
- Industry
- Enrollment
- 600 participants
Conditions and interventions
Conditions
Interventions
- Levosimendan Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2002
- Primary completion
- Not listed
- Completion
- Nov 30, 2004
- Last update posted
- Dec 14, 2006
2002 – 2004
United States locations
- U.S. sites
- 132
- U.S. states
- 38
- U.S. cities
- 100
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cardiovascular Associates/Office of Clinical Research | Birmingham | Alabama | 35209 | — |
| Cardiology, P.C. Research | Birmingham | Alabama | 35211 | — |
| University Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Oracle Research-The Heart Center | Huntsville | Alabama | 35801 | — |
| Providence Hospital Heart Failure Clinic | Mobile | Alabama | 36685 | — |
| Arizona Heart Institute | Phoenix | Arizona | 85006 | — |
| Sarver Heart Center - University of Arizona Health Science | Tucson | Arizona | 85724 | — |
| Central Arkansas Veterans Healthcare System | Little Rock | Arkansas | 72205 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Central Cardiology Medical Center | Bakersfield | California | 93301 | — |
| Cardiovascular Medical Group & Research Institute | Beverly Hills | California | 90210 | — |
| San Diego Cardiovascular Research | Encinitas | California | 92024 | — |
| Apex Cardiology Consultants, Inc. | Inglewood | California | 90301 | — |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| Los Angeles County/USC Medical Center | Los Angeles | California | 90033 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| VA Greater Los Angeles Healthcare System | Los Angeles | California | 90073 | — |
| Merced Heart Associates | Merced | California | 95340 | — |
| A.R.I. Clinical Trials, Inc. | Redondo Beach | California | 90277 | — |
| Sacramento Heart and Vascular Research Center | Sacramento | California | 95825 | — |
| UCSD Medical Center, University of California | San Diego | California | 92103 | — |
| San Diego Cardiac Center | San Diego | California | 92123 | — |
| VA San Diego Healthcare System | San Diego | California | 92161 | — |
| VA Hospital of San Francisco | San Francisco | California | 94121 | — |
| Denver Health Medical Center | Denver | Colorado | 80204 | — |
| University of Connecticut Health Center | Farmington | Connecticut | 06030 | — |
| Yale University School of Medicine/Heart Failure Center | New Haven | Connecticut | 06510 | — |
| Hospital of Saint Raphael | New Haven | Connecticut | 06511 | — |
| Christiana Care Health System | Newark | Delaware | 19718 | — |
| Washington Hospital Center - Cardiac Surgery Department | Washington D.C. | District of Columbia | 20010 | — |
| George Washington University | Washington D.C. | District of Columbia | 20037 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| Jacksonville Heart Center PA-Baptist Office | Jacksonville | Florida | 32207 | — |
| Jacksonville Heart Center,PA | Jacksonville | Florida | 32250 | — |
| Watson Clinic Center for Research | Lakeland | Florida | 33805 | — |
| MIMA Century Research Associates | Melbourne | Florida | 32901 | — |
| Jackson Memorial Hospital | Miami | Florida | 33102 | — |
| Miami Research & Education Foundation | Miami | Florida | 33156 | — |
| The Ford Research Institute PA/NW Florida Heart Group PA | Pensacola | Florida | 32514 | — |
| Victor Howard M.D., P.A. Heart Research Center | Port Charlotte | Florida | 33952 | — |
| Heart & Vascular Institute of Florida | St. Petersburg | Florida | 33701 | — |
| Florida Cardiovascular Institute | Tampa | Florida | 33609 | — |
| Augusta Cardiology Clinic, P.C. | Augusta | Georgia | 30901 | — |
| Memorial Health University Medical Center Research Center | Savannah | Georgia | 31405 | — |
| Northwestern Memorial Hospital/Heart Failure Program | Chicago | Illinois | 60611 | — |
| Rush-Presbyterian-St. Luke's Medical Center | Chicago | Illinois | 60612 | — |
| Elgin Cardiology Associates | Elgin | Illinois | 60120 | — |
| Midwest Heart Research Foundation | Lombard | Illinois | 60148 | — |
| Heart Care Midwest | Peoria | Illinois | 61603 | — |
| Clarian Health - Methodist Research Institute Inc. | Indianapolis | Indiana | 46202 | — |
| Iowa Heart Center | Des Moines | Iowa | 50314 | — |
| University Hospital, Iowa City | Iowa City | Iowa | 52242 | — |
| Via Christi Research Inc. dba PriVia | Wichita | Kansas | 67214 | — |
| Gill Heart Institute/University of Kentucky | Lexington | Kentucky | 40536 | — |
| Louisiana Heart Center | Chalmette | Louisiana | 70043 | — |
| New Orleans Clinical Trial Management, Inc. | Covington | Louisiana | 70433 | — |
| Tulane University Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Cardiac Centers of Louisiana, LLC | Shreveport | Louisiana | 71135 | — |
| Medical Research Institute | Slidell | Louisiana | 70458 | — |
| University of Maryland Hospital | Baltimore | Maryland | 21201 | — |
| John Hopkins Bayview Medical Center | Baltimore | Maryland | 21224 | — |
| The Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| University of Michigan Medical Center, CACR | Ann Arbor | Michigan | 48109 | — |
| Wayne State University | Detroit | Michigan | 48201 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Nisus Research/Northern Michigan Hospital | Petoskey | Michigan | 49770 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| Michigan Heart P.C. | Ypsilanti | Michigan | 48197 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55414 | — |
| VA Medical Center - Cardiology Department | Minneapolis | Minnesota | 55417 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| St. Paul Clinic | Saint Paul | Minnesota | 55102 | — |
| University Hospitals Clinic | Columbus | Missouri | 65212 | — |
| Saint Louis University Hospital | St Louis | Missouri | 63110 | — |
| International Heart Institute Montana Foundation | Missoula | Montana | 59802 | — |
| Alegent Health Heart and Vascular Institute | Omaha | Nebraska | 68122 | — |
| The Creighton Cardiac Center | Omaha | Nebraska | 68131 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Heart Failure & Transplantation Program | Newark | New Jersey | 07112 | — |
| Heart Hospital of New Mexico - NW Heart Institute | Albuquerque | New Mexico | 87106 | — |
| Beth Israel Medical Center NY/Phillips Ambulatory Care Center | New York | New York | 10003 | — |
| St. Vincent's Hospital | New York | New York | 10011 | — |
| Columbia-Presbyterian Medical Center | New York | New York | 10032 | — |
| Jack D. Weiler Hospital/Albert Einstein Hospital | The Bronx | New York | 10461 | — |
| Montefiore Medical Center/Cardiology Department | The Bronx | New York | 10467 | — |
| University Of North Carolina | Chapel Hill | North Carolina | 27599 | — |
| The Lindner Center | Cincinnati | Ohio | 45219 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Foundation/Department of Cardiology | Cleveland | Ohio | 44195 | — |
| OSU Medical Center-Center Wellness & Prevention | Columbus | Ohio | 43210 | — |
| The Toledo Clinic & Outpatient Surgery | Toledo | Ohio | 43623 | — |
| Toledo Clinic & Outpatient Surgery/Department of Cardiology | Toledo | Ohio | 43623 | — |
| Oklahoma Foundation-Cardiovascular | Oklahoma City | Oklahoma | 73104 | — |
| University Health Science Center/Cardio Section | Oklahoma City | Oklahoma | 73104 | — |
| Hillsboro Cardiology, PC | Hillsboro | Oregon | 97123 | — |
| Oregon Health & Science University | Portland | Oregon | 97201 | — |
| Providence Portland Medical Center/Heart Failure Clinic | Portland | Oregon | 97213 | — |
| Geisinger Health System | Danville | Pennsylvania | 17822 | — |
| The Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Heart Group | Lancaster | Pennsylvania | 17603 | — |
| Hahnemann University Hospital/HF and Transplant Center | Philadelphia | Pennsylvania | 19102 | — |
| Universtiy of PA Health System | Philadelphia | Pennsylvania | 19104 | — |
| Jefferson Heart Institute | Philadelphia | Pennsylvania | 19107 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Buxmont Cardiology Associates | Sellersville | Pennsylvania | 18960 | — |
| Cardiology Associates of West Reading | West Reading | Pennsylvania | 19611 | — |
| Rhode Island Hospital/University Cardiology | Providence | Rhode Island | 02905 | — |
| Baptist Clinical Research Center | Memphis | Tennessee | 38120 | — |
| Cardiology Group, P.C. | Tullahoma | Tennessee | 37388 | — |
| Austin-Cardiovascular Associates | Austin | Texas | 78705 | — |
| Dallas VA Medical Center | Dallas | Texas | 75216 | — |
| Cardiopulmonary Research Science & Technology Institute | Dallas | Texas | 75230 | — |
| Cardiovascular Research Institute of Dallas | Dallas | Texas | 75231 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Houston VA Medical Center | Houston | Texas | 77030 | — |
| St. Luke's Episcopal Hospital/Texas Heart Institute | Houston | Texas | 77030 | — |
| Heart Specialists | Nassau Bay | Texas | 77058 | — |
| University of Texas Health Sciences | San Antonio | Texas | 78229 | — |
| UTHCT/Center for Clinical Research | Tyler | Texas | 75708 | — |
| Sentara Norfolk General Hospital | Norfolk | Virginia | 23507 | — |
| Carilion Department of Clinical Research | Roanoke | Virginia | 24011 | — |
| DUCCS Research of South Boston | South Boston | Virginia | 24592 | — |
| Overlake Hospital Medical Center | Bellevue | Washington | 98004 | — |
| University of Washington | Seattle | Washington | 98195 | — |
| Inland Cardiology Associates | Spokane | Washington | 99204 | — |
| Southwest Washington Medical Center | Vancouver | Washington | 98664 | — |
| Beloit Clinic, SC | Beloit | Wisconsin | 53511 | — |
| St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 34 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00048425, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 14, 2006 · Synced May 12, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00048425 live on ClinicalTrials.gov.