Safety and Efficacy Study of Once and Twice Daily Doses of MCC-135 in Subjects With Congestive Heart Failure.
Public ClinicalTrials.gov record NCT00050076. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Double-Blind, Randomized, Exploratory, Placebo-Controlled Study of Efficacy, Safety, and Tolerability of MCC-135 Comparing QD vs BID Doses in Subjects With Congestive Heart Failure, NYHA Class II/III
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the effect of two different doses of MCC-135, once daily (QD) or twice daily (BID), on the disease state and the quality of life in subjects with congestive heart failure.
Study identification
- NCT ID
- NCT00050076
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 204 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2002 (Type not available)
- Primary completion
- Aug 2003 (Actual)
- Completion
- Aug 2003 (Actual)
- Last update posted
- Feb 2, 2012
2002 – 2003
United States locations
- U.S. sites
- 53
- U.S. states
- 20
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Maricopa Medical Center | Phoenix | Arizona | 85008 | — |
| University of Arizona Medical Center | Tucson | Arizona | 85724 | — |
| Capitol Intervention Cardiology | Carmichael | California | 95608 | — |
| San Diego Cardiovascular | Encinitas | California | 92024 | — |
| LAC & USC Medical Center | Los Angeles | California | 90033 | — |
| ARI Clinical Trials, Inc Arrhythmia Research & Cardiology Health Center | Redondo Beach | California | 90027 | — |
| Clinical Trials Research | Roseville | California | 95661 | — |
| Sacramento Heart & Vascular Medical Associates | Sacramento | California | 95825 | — |
| University of California San Diego | San Diego | California | 92103 | — |
| Apex Research Institute | Santa Ana | California | 92705 | — |
| Cardiology Consultants PA | Daytona Beach | Florida | 32114 | — |
| Cardiology Associates of Fort Lauderdale | Fort Lauderdale | Florida | 33308 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Cardiovascular Center of Sarasota | Sarasota | Florida | 34239 | — |
| Southern Clinical Research & Management | Augusta | Georgia | 30904 | — |
| Medical Group of Fort Wayne, PC | Fort Wayne | Indiana | 46804 | — |
| Medical Center Cardiologist | Louisville | Kentucky | 40202 | — |
| Louisville Cardiology Medical Group, PSC | Louisville | Kentucky | 40207 | — |
| Louisiana Heart Center | Chalmette | Louisiana | 70043 | — |
| New Orleans Center for Clinical Research | New Orleans | Louisiana | 70119 | — |
| Ochsner Clinic | New Orleans | Louisiana | 70121 | — |
| Cardiac Center of Louisiana, LLC | Shreveport | Louisiana | 71103 | — |
| Cardiology Associates, PC | Annapolis | Maryland | 21114 | — |
| University of Maryland Hospital | Baltimore | Maryland | 21201 | — |
| Cardiovascular Consultants, PA | Takoma Park | Maryland | 20901 | — |
| University of Massachusettes | Worcester | Massachusetts | 01655 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Bryan LGH Heart Institute | Lincoln | Nebraska | 68510 | — |
| Alegent Health Immanuel Medical Center | Omaha | Nebraska | 68122 | — |
| Not listed | Millburn | New Jersey | 07041 | — |
| South Jersey Heart Group | Sewell | New Jersey | 08080 | — |
| Buffalo General Hospital | Buffalo | New York | 14203 | — |
| Heart Care Center East | Fayetteville | New York | 13066 | — |
| Hudson Valley Clinical Research | Kingston | New York | 12401 | — |
| Saint Vincent Catholic Medical Center | New York | New York | 10011 | — |
| University of Rochester | Rochester | New York | 14618 | — |
| Albert Einstein College of Medicine | The Bronx | New York | 10461 | — |
| Sterling Research Group | Cincinnati | Ohio | 45219 | — |
| North Ohio Research, Ltd. | Lorain | Ohio | 44053 | — |
| City Cardiology Associates, Inc. | Stow | Ohio | 44224 | — |
| Chestnut Hill Cardiology, Ltd. | Flourtown | Pennsylvania | 19031 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Carolina Research Associates | Columbia | South Carolina | 29206 | — |
| The Stern Cardiovascular Center | Memphis | Tennessee | 38120 | — |
| Cardiovascular Research Institute of Dallas Medical Center - Cardiologist Research Foundation | Dallas | Texas | 75231 | — |
| Med-Tech Research | Houston | Texas | 77055 | — |
| Not listed | Nassau Bay | Texas | 77058 | — |
| Tyler Cardiovascular Consultants | Tyler | Texas | 75701 | — |
| Cardiovascular Associates, Ltd. | Chesapeake | Virginia | 23320 | — |
| Wisconsin Center for Clinical Research, LLC | Elkhorn | Wisconsin | 53121 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00050076, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 2, 2012 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00050076 live on ClinicalTrials.gov.